General Information of the Compound
| Compound ID |
CP0136667
|
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compound Name |
2-[2-[6-(5-fluoro-6-methoxypyridin-3-yl)-4-methylquinazolin-8-yl]oxyethyl-propan-2-ylamino]-N-hydroxypyrimidine-5-carboxamide
Show/Hide
|
||||||||||||||||||
| Structure |
|
||||||||||||||||||
| Formula |
C25H26FN7O4
|
||||||||||||||||||
| Molecular Weight |
507.526
|
||||||||||||||||||
| Canonical SMILES |
COc1ncc(cc1F)-c1cc(OCCN(C(C)C)c2ncc(cn2)C(=O)NO)c2ncnc(C)c2c1
Show/Hide
|
||||||||||||||||||
| InChI |
InChI=1S/C25H26FN7O4/c1-14(2)33(25-28-11-18(12-29-25)23(34)32-35)5-6-37-21-9-16(7-19-15(3)30-13-31-22(19)21)17-8-20(26)24(36-4)27-10-17/h7-14,35H,5-6H2,1-4H3,(H,32,34)
Show/Hide
|
||||||||||||||||||
| InChIKey |
QLZIGDJCZXPNRE-UHFFFAOYSA-N
|
||||||||||||||||||
| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
|
||||||||||||||||||
| Click to Show/Hide the External Link(s) of This Compound | |||||||||||||||||||
| PubChem ID | |||||||||||||||||||
| ChEMBL ID | |||||||||||||||||||
Map of Molecular Bioactivity Related to the Compound
|
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
|
|---|
Table of Molecular Bioactivities Related to the Compound