General Information of the Compound
Compound ID
CP0134486
Compound Name
(6R)-N-[(2S)-5-(ethylamino)-1-hydroxy-5-oxopentan-2-yl]-N,9-dimethyl-6-(oxan-4-yl)-5,6,7,8-tetrahydrocarbazole-3-carboxamide
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Structure
Formula
C27H39N3O4
Molecular Weight
469.626
Canonical SMILES
CCNC(=O)CC[C@@H](CO)N(C)C(=O)c1ccc2n(C)c3CC[C@H](Cc3c2c1)C1CCOCC1
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InChI
InChI=1S/C27H39N3O4/c1-4-28-26(32)10-7-21(17-31)29(2)27(33)20-6-9-25-23(16-20)22-15-19(5-8-24(22)30(25)3)18-11-13-34-14-12-18/h6,9,16,18-19,21,31H,4-5,7-8,10-15,17H2,1-3H3,(H,28,32)/t19-,21+/m1/s1
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InChIKey
GMNVCBCXIRKAHE-CTNGQTDRSA-N
Physicochemical Property
logP
3.059
Rotatable Bonds
8
Heavy Atom Count
34
Polar Areas
83.8
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 57606091
ChEMBL ID
CHEMBL2029736
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01298, Cannabinoid receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 78.7 nM
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