General Information of the Compound
| Compound ID |
CP0132626
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| Compound Name |
N-carbamoyl-2-[(5S)-9-fluoro-2-[6-(morpholine-4-carbonyl)pyridin-3-yl]-5H-chromeno[2,3-b]pyridin-5-yl]-2-methylpropanamide
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| Structure |
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| Formula |
C27H26FN5O5
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| Molecular Weight |
519.533
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| Canonical SMILES |
CC(C)([C@@H]1c2ccc(nc2Oc2c(F)cccc12)-c1ccc(nc1)C(=O)N1CCOCC1)C(=O)NC(N)=O
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| InChI |
InChI=1S/C27H26FN5O5/c1-27(2,25(35)32-26(29)36)21-16-4-3-5-18(28)22(16)38-23-17(21)7-9-19(31-23)15-6-8-20(30-14-15)24(34)33-10-12-37-13-11-33/h3-9,14,21H,10-13H2,1-2H3,(H3,29,32,35,36)/t21-/m0/s1
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| InChIKey |
MDMKCVXYKPOLIM-NRFANRHFSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00967, Glucocorticoid receptor