General Information of the Compound
Compound ID
CP0127379
Compound Name
4-[[4-fluoro-3-[4-(4-iodobenzoyl)piperazine-1-carbonyl]phenyl]methyl]-2H-phthalazin-1-one
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Structure
Formula
C27H22FIN4O3
Molecular Weight
596.4
Canonical SMILES
Fc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1C(=O)N1CCN(CC1)C(=O)c1ccc(I)cc1
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InChI
InChI=1S/C27H22FIN4O3/c28-23-10-5-17(16-24-20-3-1-2-4-21(20)25(34)31-30-24)15-22(23)27(36)33-13-11-32(12-14-33)26(35)18-6-8-19(29)9-7-18/h1-10,15H,11-14,16H2,(H,31,34)
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InChIKey
QOCIPUHZHXLQMK-UHFFFAOYSA-N
Physicochemical Property
logP
3.8558
Rotatable Bonds
4
Heavy Atom Count
36
Polar Areas
86.37
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 118905796
ChEMBL ID
CHEMBL3735979