General Information of the Compound
Compound ID
CP0113102
Compound Name
2-Ethyl-1,1-dioxo-1,2,3,4,6,7-hexahydro-5,8-dioxa-1lambda*6*-thia-2-aza-anthracene-3-carboxylic acid (1-formyl-3-methyl-butyl)-amide
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Structure
Formula
C19H26N2O6S
Molecular Weight
410.492
Canonical SMILES
CCN1C(Cc2cc3OCCOc3cc2S1(=O)=O)C(=O)N[C@@H](CC(C)C)C=O
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InChI
InChI=1S/C19H26N2O6S/c1-4-21-15(19(23)20-14(11-22)7-12(2)3)8-13-9-16-17(27-6-5-26-16)10-18(13)28(21,24)25/h9-12,14-15H,4-8H2,1-3H3,(H,20,23)/t14-,15?/m0/s1
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InChIKey
IEOOUUUGLBHOIM-MLCCFXAWSA-N
Physicochemical Property
logP
1.1229
Rotatable Bonds
6
Heavy Atom Count
28
Polar Areas
102.01
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44344296
ChEMBL ID
CHEMBL115572
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01697, Calpain-1 catalytic subunit
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000116 MOLT-4 Homo sapiens (Human)  1
1
IC50 > 3000 nM
   TI
   LI
   LO
   TS