General Information of the Compound
Compound ID
CP0095521
Compound Name
6,11-dihydrothiochromeno[4,3-b]indole
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Synonyms
(1)Benzothiopyrano(4,3-b)indole, 6,11-dihydro-
4079-26-9
6,11-Dihydro-5-thia-11-aza-benzo(a)fluorene
6,11-Dihydro[1]benzothiopyrano[4,3-b]indole
6,11-dihydrothiochromeno[4,3-b]indole
6,3-b]indole
AC1L6RUM
AKOS024457313
AOB5548
B7208
BCP24885
BDBM50208823
BS0260
CHEMBL180917
CTK4I3773
MFCD05664738
MolPort-003-959-269
NCGC00165868-01
NSC 168807
NSC-168807
NSC168807
PD 146176
PD 146176, &gt
PD-146176
SCHEMBL1986281
ZINC6892
[1]Benzothiopyrano[4, 6,11-dihydro-
pd146176
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Structure
Formula
C15H11NS
Molecular Weight
237.327
Canonical SMILES
C1Sc2ccccc2-c2[nH]c3ccccc3c12
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InChI
InChI=1S/C15H11NS/c1-3-7-13-10(5-1)12-9-17-14-8-4-2-6-11(14)15(12)16-13/h1-8,16H,9H2
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InChIKey
ZGOOPZVQMLHPFM-UHFFFAOYSA-N
CAS
4079-26-9
Physicochemical Property
logP
4.4406
Rotatable Bonds
0
Heavy Atom Count
17
Polar Areas
15.79
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
1
Complexity
17

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 297589
SID: 15121833
ChEMBL ID
CHEMBL180917
Clinical Information about the Compound
Drug 1 ( PD-146176 )
Drug Name PD-146176
Indication
Arteriosclerosis
Terminated
Target(s)
Arachidonate 5-lipoxygenase (5-LOX)
Modulator