General Information of the Compound
| Compound ID |
CP0091585
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| Compound Name |
7-((6-chloropyridin-3-yl)methoxy)-2-(4-((6-chloropyridin-3-yl)methoxy)phenyl)-4H-chromen-4-one
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| Structure |
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| Formula |
C27H18Cl2N2O4
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| Molecular Weight |
505.357
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| Canonical SMILES |
Clc1ccc(COc2ccc(cc2)-c2cc(=O)c3ccc(OCc4ccc(Cl)nc4)cc3o2)cn1
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| InChI |
InChI=1S/C27H18Cl2N2O4/c28-26-9-1-17(13-30-26)15-33-20-5-3-19(4-6-20)24-12-23(32)22-8-7-21(11-25(22)35-24)34-16-18-2-10-27(29)31-14-18/h1-14H,15-16H2
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| InChIKey |
ACEACBDHWOKIAR-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01466, Telomerase reverse transcriptase
Cell Viability or Cytotoxicity Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000250 | SGC-7901 | Homo sapiens (Human) | 1 |
| 1 |
IC50 = 36508.62751 nM
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TI
LI
LO
TS
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