General Information of the Compound
Compound ID
CP0070572
Compound Name
4-(1H-benzimidazol-2-yl)-1,3-thiazole
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Synonyms
2-(1,3-Thiazol-4-yl)-1H-benzimidazole
2-(1,3-Thiazol-4-yl)benzimidazole
2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazole
2-(4'-Thiazolyl)benzimidazole
2-(4-Thiazolyl)-1H-benzimidazole
2-(4-Thiazolyl)benzimidazole
2-(Thiazol-4-yl)benzimidazole
2-Thiazol-4-yl-1H-benzoimidazole
2-Thiazole-4-ylbenzimidazole
2-[4-Thiazoly]benzimidazole
4-(1H-benzimidazol-2-yl)-1,3-thiazole
4-(2-Benzimidazolyl)thiazole
APL-luster
Arbotect (TN)
Biogard
Bioguard
Bovizole
Captan T
Chemviron TK 100
Cropasal
Drawipas
E-Z-Ex
Eprofil
Equivet TZ
Equizole
Equizole A
G 491
Helmindrax octelmin
Hokustar HP
Hymush
Lombristop
MK 360
MK-360
Mertec
Mertect
Mertect 160
Mertect 340f
Mertect lsp
Metasol TK 100
Metasol TK-100
Metasol tk 10
Mintesol
Mintezol
Mintezol (TN)
Mintezol, Equizole, Thiabendazole
Mintezole
Minzolum
Mycozol
Nemacin
Nemapan
Omnizole
Ormogal
PS1057_SUPELCO
Pitrizet
Polival
RPH
RTU Flowable Fungicide
Sanaizol 100
Sistesan
Storite
Syntol M100
TBZ 6
TBZ 60W
TBZ-6
Tbdz
Tebuzate
Tecto
Tecto 10P
Tecto 40F
Tecto 60
Tecto B
Tecto rph
Testo
Thiaben
Thiabendazol
Thiabendazole
Thiabendazole (USP)
Thiabendazole [BSI:ISO]
Thiabendazole [USAN:BAN]
Thiabendazolum
Thiabendole
Thiabenzazole
Thiabenzole
Thibendole
Thibenzol
Thibenzole
Thibenzole 200
Thibenzole att
Thiprazole
Tiabenda
Tiabendazol
Tiabendazol [INN-Spanish, French]
Tiabendazole
Tiabendazole (JAN/INN)
Tiabendazolum
Tiabendazolum [INN-Latin]
Tibimix 20
Tobaz
Top Form Wormer
Tresaderm
Tresaderm (TN)
Triasox
Tubazole
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Structure
Formula
C10H7N3S
Molecular Weight
201.254
Canonical SMILES
c1nc(cs1)-c1nc2ccccc2[nH]1
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InChI
InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)
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InChIKey
WJCNZQLZVWNLKY-UHFFFAOYSA-N
CAS
123242-33-1
145316-67-2
148-79-8
8018-04-0
8027-10-9
8028-27-1
94977-06-7
98002-42-7
Physicochemical Property
logP
2.6864
Rotatable Bonds
1
Heavy Atom Count
14
Polar Areas
41.57
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
14

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 5430
SID: 15195537
ChEMBL ID
CHEMBL625
DrugBank ID
DB00730
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01002, Cytochrome P450 1A2
 Protein Info 
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000023 BTI-Tn-5B1-4
 Cell Line Info 
Trichoplusia ni (Cabbage looper)  1
1
IC50 = 800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT00973, Methionine aminopeptidase 2
 Protein Info 
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 44700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Clinical Information about the Compound
Drug 1 ( Thiabendazole )
Drug Name Thiabendazole
Indication
Helminth infection
Approved
Dutch elm disease
Approved