General Information of the Compound
Compound ID
CP0068579
Compound Name
US8710076, E-2
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Structure
Formula
C24H22FN5O2
Molecular Weight
431.471
Canonical SMILES
C[C@@H]1CC[C@H](CN1C(=O)c1ccccc1-n1nccn1)Oc1ccnc2c(F)cccc12
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InChI
InChI=1S/C24H22FN5O2/c1-16-9-10-17(32-22-11-12-26-23-19(22)6-4-7-20(23)25)15-29(16)24(31)18-5-2-3-8-21(18)30-27-13-14-28-30/h2-8,11-14,16-17H,9-10,15H2,1H3/t16-,17-/m1/s1
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InChIKey
BVUZOFDSUCGTDO-IAGOWNOFSA-N
Physicochemical Property
logP
4.0267
Rotatable Bonds
4
Heavy Atom Count
32
Polar Areas
73.14
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
6
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 46212134
SID: 96066501
ChEMBL ID
CHEMBL3394842