General Information of the Compound
Compound ID
CP0066695
Compound Name
6-[(E)-2-(1,3-benzodioxol-5-yl)ethenyl]-1,3,5-trimethylpyrrolo[3,2-d]pyrimidine-2,4-dione
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Structure
Formula
C18H17N3O4
Molecular Weight
339.351
Canonical SMILES
Cn1c(\C=C\c2ccc3OCOc3c2)cc2n(C)c(=O)n(C)c(=O)c12
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InChI
InChI=1S/C18H17N3O4/c1-19-12(6-4-11-5-7-14-15(8-11)25-10-24-14)9-13-16(19)17(22)21(3)18(23)20(13)2/h4-9H,10H2,1-3H3/b6-4+
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InChIKey
LQPREAQKIYKQRO-GQCTYLIASA-N
Physicochemical Property
logP
1.4748
Rotatable Bonds
2
Heavy Atom Count
25
Polar Areas
67.39
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
7
Complexity
25

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 71563171
SID: 163563620
ChEMBL ID
CHEMBL2312991
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 467.3 nM
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   LI
   LO
   TS