General Information of the Compound
Compound ID
CP0063111
Compound Name
3-(2-methylbut-3-yn-2-yl)-N-[4-methyl-3-[(3-methyl-4-oxoquinazolin-6-yl)amino]phenyl]benzamide
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Structure
Formula
C28H26N4O2
Molecular Weight
450.542
Canonical SMILES
Cc1ccc(NC(=O)c2cccc(c2)C(C)(C)C#C)cc1Nc1ccc2ncn(C)c(=O)c2c1
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InChI
InChI=1S/C28H26N4O2/c1-6-28(3,4)20-9-7-8-19(14-20)26(33)31-22-11-10-18(2)25(16-22)30-21-12-13-24-23(15-21)27(34)32(5)17-29-24/h1,7-17,30H,2-5H3,(H,31,33)
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InChIKey
WROPEIVESXJWPS-UHFFFAOYSA-N
Physicochemical Property
logP
5.14862
Rotatable Bonds
5
Heavy Atom Count
34
Polar Areas
76.02
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11633786
SID: 16736957
ChEMBL ID
CHEMBL4203441