General Information of the Compound
Compound ID
CP0060990
Compound Name
MLS000733369
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Structure
Formula
C22H25N3O3
Molecular Weight
379.46
Canonical SMILES
O=C(NC1CCCCCCC1)c1cc(COc2ccc3ncccc3c2)on1
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InChI
InChI=1S/C22H25N3O3/c26-22(24-17-8-4-2-1-3-5-9-17)21-14-19(28-25-21)15-27-18-10-11-20-16(13-18)7-6-12-23-20/h6-7,10-14,17H,1-5,8-9,15H2,(H,24,26)
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InChIKey
CUYIDLFZPOFPFS-UHFFFAOYSA-N
Physicochemical Property
logP
4.6445
Rotatable Bonds
5
Heavy Atom Count
28
Polar Areas
77.25
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 16189691
ChEMBL ID
CHEMBL1399478
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06101, Latent membrane protein 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
AC50 = 1296 nM
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