General Information of the Compound
Compound ID
CP0058246
Compound Name
8-hydroxyquinoline-5-carboxylic acid
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Synonyms
2184AH
4bio
4ie4
4jht
5-Carboxy-8-hydroxyquinoline
5-Quinolinecarboxylic acid, 8-hydroxy-
5-carboxy-8HQ
5852-78-8
8-Hydroxy-5-quinolinecarboxylic acid
8-Hydroxyquinoline-5-Carboxylic Acid
8XQ
AC1LA0UV
AKOS016371793
AOB6499
BCP16996
BDBM50396018
CHEBI:93239
CHEMBL1230640
CTK1E0142
DTXSID20207236
GTPL8230
HMS3653E21
Hydroxyqunoline analog 1
IOX 1
IOX-1
IOX1
IOX1, &gt
JGRPKOGHYBAVMW-UHFFFAOYSA-N
JM015YQC1C
KS-00000PPH
MLS002729056
MolPort-006-673-354
PMID25468267-Compound-41
SCHEMBL6068195
UNII-JM015YQC1C
ZINC5933707
s7234
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Structure
Formula
C10H7NO3
Molecular Weight
189.17
Canonical SMILES
OC(=O)c1ccc(O)c2ncccc12
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InChI
InChI=1S/C10H7NO3/c12-8-4-3-7(10(13)14)6-2-1-5-11-9(6)8/h1-5,12H,(H,13,14)
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InChIKey
JGRPKOGHYBAVMW-UHFFFAOYSA-N
Physicochemical Property
logP
1.6386
Rotatable Bonds
1
Heavy Atom Count
14
Polar Areas
70.42
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Complexity
14

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 459617
ChEMBL ID
CHEMBL1230640
Clinical Information about the Compound
Drug 1 ( Hydroxyqunoline analog 1 )
Drug Name Hydroxyqunoline analog 1
Target(s)
Lysine-specific demethylase 4E (KDM4E)
 Target Info 
Inhibitor
Drug 2 ( IOX1 )
Drug Name IOX1
Target(s)
Lysine-specific demethylase 6B (KDM6B)
 Target Info 
Inhibitor
HIF-prolyl hydroxylase 2 (HPH-2)
 Target Info 
Inhibitor
Lysine-specific demethylase 4C (KDM4C)
 Target Info 
Inhibitor
Lysine-specific demethylase 3A (KDM3A)
 Target Info 
Inhibitor