General Information of the Compound
Compound ID
CP0055011
Compound Name
US8742106, 1.6
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Structure
Formula
C23H23F3N6O2
Molecular Weight
472.471
Canonical SMILES
C[C@H](NC(=O)COc1cc(c2c(nn(C)c2n1)-c1ccccc1)C(F)(F)F)c1c(C)n[nH]c1C
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InChI
InChI=1S/C23H23F3N6O2/c1-12(19-13(2)29-30-14(19)3)27-17(33)11-34-18-10-16(23(24,25)26)20-21(15-8-6-5-7-9-15)31-32(4)22(20)28-18/h5-10,12H,11H2,1-4H3,(H,27,33)(H,29,30)/t12-/m0/s1
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InChIKey
KNSSBXCHRPNPDS-LBPRGKRZSA-N
Physicochemical Property
logP
4.25024
Rotatable Bonds
6
Heavy Atom Count
34
Polar Areas
97.72
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 70817239
ChEMBL ID
CHEMBL3634015