General Information of the Compound
| Compound ID |
CP0043610
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| Compound Name |
4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-yl-1,3-thiazol-2-yl)amino]phenyl]benzamide
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| Synonyms |
4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]benzamide
790299-79-5
AB 1010
AB-1010
AB1010
C28H30N6OS
CHEBI:63450
CHEMBL1908391
M59NC4E26P
Masatinib
Masitinib
Masitinib (AB1010)
Masitinib (INN)
Masitinib [INN]
Masivet
N-(4-Methyl-3-((4-(pyridin-3-yl)thiazol-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide
N-(4-methyl-3-(4-(pyridin-3-yl)thiazol-2-ylamino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide
Q-201339
UNII-M59NC4E26P
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| Structure |
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| Formula |
C28H30N6OS
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| Molecular Weight |
498.656
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| Canonical SMILES |
CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nc(cs3)-c3cccnc3)c2)CC1
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| InChI |
InChI=1S/C28H30N6OS/c1-20-5-10-24(16-25(20)31-28-32-26(19-36-28)23-4-3-11-29-17-23)30-27(35)22-8-6-21(7-9-22)18-34-14-12-33(2)13-15-34/h3-11,16-17,19H,12-15,18H2,1-2H3,(H,30,35)(H,31,32)
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| InChIKey |
WJEOLQLKVOPQFV-UHFFFAOYSA-N
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| CAS |
790299-79-5
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Clinical Information about the Compound
Drug 1 ( Masitinib )
| Drug Name | Masitinib | ||
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| Company | AB Science | ||
| Indication | |||
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