General Information of the Compound
Compound ID
CP0043425
Compound Name
2-(4-ethoxy-3-(trifluoromethyl)phenyl)-9H-purine-6-carbonitrile
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Structure
Formula
C15H10F3N5O
Molecular Weight
333.273
Canonical SMILES
CCOc1ccc(cc1C(F)(F)F)-c1nc(C#N)c2[nH]cnc2n1
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InChI
InChI=1S/C15H10F3N5O/c1-2-24-11-4-3-8(5-9(11)15(16,17)18)13-22-10(6-19)12-14(23-13)21-7-20-12/h3-5,7H,2H2,1H3,(H,20,21,22,23)
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InChIKey
VKSGXYBWSOFNOU-UHFFFAOYSA-N
Physicochemical Property
logP
3.30908
Rotatable Bonds
3
Heavy Atom Count
24
Polar Areas
87.48
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
24

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 46911633
SID: 99372636
ChEMBL ID
CHEMBL1209531