General Information of the Compound
| Compound ID |
CP0024991
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| Compound Name |
LY2606368
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| Synonyms |
1234015-52-1
5-((5-(2-(3-aminopropoxy)-6-methoxyphenyl)-1H-pyrazol-3-yl)amino)pyrazine-2-carbonitrile
5-({5-[2-(3-aminopropoxy)-6-methoxyphenyl]-1H-pyrazol-3-yl}amino)pyrazine-2-carbonitrile
5-[[5-[2-(3-aminopropoxy)-6-methoxyphenyl]-1H-pyrazol-3-yl]amino]pyrazine-2-carbonitrile
820NH671E6
AOB87325
CHEMBL3544911
DOTGPNHGTYJDEP-UHFFFAOYSA-N
EX-A758
GTPL9549
LY-2606368
LY2606368
Prexasertib
Prexasertib [USAN]
SCHEMBL18989301
SCHEMBL19457660
SCHEMBL1975451
UNII-820NH671E6
ZINC95837013
prexasertib
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| Structure |
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| Formula |
C18H19N7O2
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| Molecular Weight |
365.397
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| Canonical SMILES |
COc1cccc(OCCCN)c1-c1cc(Nc2cnc(cn2)C#N)n[nH]1
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| InChI |
InChI=1S/C18H19N7O2/c1-26-14-4-2-5-15(27-7-3-6-19)18(14)13-8-16(25-24-13)23-17-11-21-12(9-20)10-22-17/h2,4-5,8,10-11H,3,6-7,19H2,1H3,(H2,22,23,24,25)
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| InChIKey |
DOTGPNHGTYJDEP-UHFFFAOYSA-N
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| CAS |
1234015-52-1
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Table of Molecular Bioactivities Related to the Compound
Clinical Information about the Compound