General Information of the Compound
| Compound ID |
CP0016817
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| Compound Name |
1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea
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| Synonyms |
IGF-1R inhibitor II
PQ 401
PQ-401
PQ401
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| Structure |
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| Formula |
C18H16ClN3O2
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| Molecular Weight |
341.798
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| Canonical SMILES |
COc1ccc(Cl)cc1NC(=O)Nc1cc(C)nc2ccccc12
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| InChI |
InChI=1S/C18H16ClN3O2/c1-11-9-15(13-5-3-4-6-14(13)20-11)21-18(23)22-16-10-12(19)7-8-17(16)24-2/h3-10H,1-2H3,(H2,20,21,22,23)
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| InChIKey |
YBLWOZUPHDKFOT-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Table of Molecular Bioactivities Related to the Compound
Clinical Information about the Compound