General Information of the Compound
Compound ID
CP0013907
Compound Name
US9145412, Table 1, Compound 23
    Show/Hide
Structure
Formula
C24H23N5OS
Molecular Weight
429.549
Canonical SMILES
Nc1ccc(cc1NC(=O)c1ccc2nc(ccc2c1)N1CCNCC1)-c1cccs1
    Show/Hide
InChI
InChI=1S/C24H23N5OS/c25-19-6-3-17(22-2-1-13-31-22)15-21(19)28-24(30)18-4-7-20-16(14-18)5-8-23(27-20)29-11-9-26-10-12-29/h1-8,13-15,26H,9-12,25H2,(H,28,30)
    Show/Hide
InChIKey
VURDNNVAYZDGDK-UHFFFAOYSA-N
Physicochemical Property
logP
4.2074
Rotatable Bonds
4
Heavy Atom Count
31
Polar Areas
83.28
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
6
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 72374405
ChEMBL ID
CHEMBL3927842