General Information of the Compound
Compound ID
CP0008237
Compound Name
5-Ethyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
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Synonyms
(+-)-5-Ethyl-5-(1-methylbutyl)barbituric acid
5-Ethyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
5-Ethyl-5-(1-methylbutyl)barbituric acid
5-Ethyl-5-(1-methylbutyl)malonylurea
5-Ethyl-5-(sec-pentyl)barbituric acid
5-ethyl-2-hydroxy-5-(1-methylbutyl)pyrimidine-4,6(1H,5H)-dione
5-ethyl-5-(pentan-2-yl)pyrimidine-2,4,6(1H,3H,5H)-trione;5-ethyl-5-pentan-2-yl-1,3-diazinane-2,4,6-trione
Aethaminalum
Dorsital
Etaminal
Ethaminal
Ethyl-propylmethylcarbinylbarbituric acid
Mebubarbital
Mebumal
Nebralin
Nembutal
Nembutal (TN)
Nembutal (VAN)
Neodorm
Neodorm (VAN)
Neodorm (new)
Pentabarbital
Pentabarbitone
Pentobarbital
Pentobarbital (USP/INN)
Pentobarbital (VAN)
Pentobarbital [USP:INN]
Pentobarbital calcium
Pentobarbital suppository dosage form
Pentobarbital, Monosodium Salt
Pentobarbitale
Pentobarbitale [DCIT]
Pentobarbitalum
Pentobarbitalum [INN-Latin]
Pentobarbitone
Pentobarbitone (VAN)
Pentobarbiturate
Pentobarbituric acid
Rivadorm
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Structure
Formula
C11H18N2O3
Molecular Weight
226.276
Canonical SMILES
CCCC(C)C1(CC)C(=O)NC(=O)NC1=O
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InChI
InChI=1S/C11H18N2O3/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16)
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InChIKey
WEXRUCMBJFQVBZ-UHFFFAOYSA-N
CAS
76-74-4
Physicochemical Property
logP
1.185
Rotatable Bonds
4
Heavy Atom Count
16
Polar Areas
75.27
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Complexity
16

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 4737
SID: 15196098
ChEMBL ID
CHEMBL448
DrugBank ID
DB00312
Clinical Information about the Compound
Drug 1 ( Pentobarbital )
Drug Name Pentobarbital
Company Oak Pharmaceuticals Inc
Indication
Insomnia
Approved
Target(s)
GABA(A) receptor alpha-1 (GABRA1)
Antagonist