General Information of the Cell Line
Cell Line ID
CL000981
Cell Line Name
MES23.5
Synonyms
MES-23.5
MES 23.5
Category
Hybrid cell line
Organism
Mus musculus (Mouse)--NCBI_TaxID=10116;
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01005, D(2) dopamine receptor
 Protein Info 
Compound ID Compound Name Compound Formula
CP0259806
 Compound Info 
(1S,5R)-3-(4-chlorophenyl)-8-[3-(4-fluorophenoxy)propyl]-8-azabicyclo[3.2.1]octan-3-ol
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C22H25ClFNO2
  1
1
Ki = 22 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0094971
 Compound Info 
(1S,5R)-3-(4-chlorophenyl)-8-[4-(4-fluorophenyl)butyl]-8-azabicyclo[3.2.1]octan-3-ol
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C23H27ClFNO
  1
1
Ki = 33 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0212873
 Compound Info 
(1R,5S)-8-[4-(1,3-benzothiazol-2-yl)butyl]-3-(4-chlorophenyl)-8-azabicyclo[3.2.1]octan-3-ol
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C24H27ClN2OS
  1
1
Ki = 44 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0077065
 Compound Info 
1-(4-chlorophenyl)-4-[4-(4-fluorophenyl)butyl]-1,4-diazepane
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C21H26ClFN2
  1
1
Ki = 139 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0079318
 Compound Info 
1-(4-chlorophenyl)-4-[3-(4-fluorophenoxy)propyl]-1,4-diazepane
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C20H24ClFN2O
  1
1
Ki = 172 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0079321
 Compound Info 
1-(1,3-benzothiazol-2-yl)-5-[(1S,5R)-3-(4-chlorophenyl)-3-hydroxy-8-azabicyclo[3.2.1]octan-8-yl]pentan-1-one
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C25H27ClN2O2S
  1
1
Ki = 180 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0077356
 Compound Info 
2-[4-[4-(4-chlorophenyl)-1,4-diazepan-1-yl]butyl]-1,3-benzothiazole
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C22H26ClN3S
  1
1
Ki = 258.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0078692
 Compound Info 
1-(4-chlorophenyl)-4-[3-(4-fluorophenyl)sulfanylpropyl]-1,4-diazepane
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C20H24ClFN2S
  1
1
Ki = 751.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0200874
 Compound Info 
2-[2-[4-(4-chlorophenyl)-1,4-diazepan-1-yl]ethyl]-5-fluoro-2,3-dihydroinden-1-one
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C22H24ClFN2O
  1
1
Ki = 1021 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0166862
 Compound Info 
1-(1,3-benzothiazol-2-yl)-5-[4-(4-chlorophenyl)-1,4-diazepan-1-yl]pentan-1-one
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C23H26ClN3OS
  1
1
Ki = 1983 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line