| Compound ID |
Compound Name |
Compound Formula |
|
CP0351155
|
4-[[4-fluoro-3-(4-methoxypiperidine-1-carbonyl)phenyl]methyl]-2H-phthalazin-1-one
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|
C22H22FN3O3
|
1
|
| 1 |
IC50 = 1.7 nM
|
|
|
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CP0120515
|
4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbonyl]-4-fluorophenyl}methyl)-1,2-dihydrophthalazin-1-one
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|
C24H23FN4O3
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
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CP0073088
|
4-[[3-[6-(cyclopropanecarbonyl)-2,6-diazaspiro[3.3]heptane-2-carbonyl]-4-fluorophenyl]methyl]-2H-phthalazin-1-one
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|
C25H23FN4O3
|
1
|
| 1 |
IC50 = 12.6 nM
|
|
|
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CP0538791
|
4-[[4-fluoro-3-(2-oxa-6-azaspiro[3.3]heptane-6-carbonyl)phenyl]methyl]-2H-phthalazin-1-one
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|
C21H18FN3O3
|
1
|
| 1 |
IC50 = 24.9 nM
|
|
|
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CP0481982
|
4-[[3-(6-azaspiro[3.4]octane-6-carbonyl)-4-fluorophenyl]methyl]-2H-phthalazin-1-one
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|
C23H22FN3O2
|
1
|
| 1 |
IC50 = 32.4 nM
|
|
|
|
CP0533311
|
4-[[3-(2-azaspiro[3.3]heptane-2-carbonyl)-4-fluorophenyl]methyl]-2H-phthalazin-1-one
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|
C22H20FN3O2
|
1
|
| 1 |
IC50 = 33.9 nM
|
|
|
|
CP0481992
|
4-[[3-(1-azaspiro[3.3]heptane-1-carbonyl)-4-fluorophenyl]methyl]-2H-phthalazin-1-one
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|
C22H20FN3O2
|
1
|
| 1 |
IC50 = 36.5 nM
|
|
|
|
CP0457957
|
4-[[3-[9-(cyclopropanecarbonyl)-3,9-diazaspiro[5.5]undecane-3-carbonyl]-4-fluorophenyl]methyl]-2H-phthalazin-1-one
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|
C29H31FN4O3
|
1
|
| 1 |
IC50 = 44.3 nM
|
|
|
|
CP0482832
|
4-[[3-(2-azaspiro[4.4]nonane-2-carbonyl)-4-fluorophenyl]methyl]-2H-phthalazin-1-one
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|
C24H24FN3O2
|
1
|
| 1 |
IC50 = 51.4 nM
|
|
|
|
CP0548781
|
4-[[3-(3-azaspiro[5.5]undecane-3-carbonyl)-4-fluorophenyl]methyl]-2H-phthalazin-1-one
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|
C26H28FN3O2
|
1
|
| 1 |
IC50 = 57.1 nM
|
|
|
|
CP0476795
|
4-[[3-(2-azaspiro[3.5]nonane-2-carbonyl)-4-fluorophenyl]methyl]-2H-phthalazin-1-one
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|
C24H24FN3O2
|
1
|
| 1 |
IC50 = 65.4 nM
|
|
|
|
CP0478962
|
4-[[3-[7-(cyclopropanecarbonyl)-2,7-diazaspiro[3.5]nonane-2-carbonyl]-4-fluorophenyl]methyl]-2H-phthalazin-1-one
Show/Hide
|
C27H27FN4O3
|
1
|
| 1 |
IC50 = 100.1 nM
|
|
|
|
CP0548782
|
4-[[3-(1,7-diazaspiro[3.5]nonane-1-carbonyl)-4-fluorophenyl]methyl]-2H-phthalazin-1-one
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|
C23H23FN4O2
|
1
|
| 1 |
IC50 = 109.5 nM
|
|
|
|
CP0538790
|
4-[[3-[6-(cyclopropanecarbonyl)-1,6-diazaspiro[3.3]heptane-1-carbonyl]-4-fluorophenyl]methyl]-2H-phthalazin-1-one
Show/Hide
|
C25H23FN4O3
|
1
|
| 1 |
IC50 = 129.7 nM
|
|
|
|
CP0481980
|
4-[[3-(2-azaspiro[4.5]decane-2-carbonyl)-4-fluorophenyl]methyl]-2H-phthalazin-1-one
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|
C25H26FN3O2
|
1
|
| 1 |
IC50 = 141.4 nM
|
|
|
|
CP0518789
|
4-[[3-[8-(cyclopropanecarbonyl)-2,8-diazaspiro[4.5]decane-2-carbonyl]-4-fluorophenyl]methyl]-2H-phthalazin-1-one
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|
C28H29FN4O3
|
1
|
| 1 |
IC50 = 224.9 nM
|
|
|
|
CP0482830
|
4-[[3-(3,9-diazaspiro[5.5]undecane-3-carbonyl)-4-fluorophenyl]methyl]-2H-phthalazin-1-one
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|
C25H27FN4O2
|
1
|
| 1 |
IC50 = 233.7 nM
|
|
|
|
CP0481983
|
4-[[3-(1-azaspiro[3.5]nonane-1-carbonyl)-4-fluorophenyl]methyl]-2H-phthalazin-1-one
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|
C24H24FN3O2
|
1
|
| 1 |
IC50 = 284 nM
|
|
|
|
CP0389554
|
4-[[3-[7-(cyclopropanecarbonyl)-1,7-diazaspiro[3.5]nonane-1-carbonyl]-4-fluorophenyl]methyl]-2H-phthalazin-1-one
Show/Hide
|
C27H27FN4O3
|
1
|
| 1 |
IC50 = 430.9 nM
|
|
|
|
CP0481994
|
tert-butyl 9-[2-fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzoyl]-3,9-diazaspiro[5.5]undecane-3-carboxylate
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|
C30H35FN4O4
|
1
|
| 1 |
IC50 = 452.8 nM
|
|
|
|
CP0563946
|
4-[[3-(1,6-diazaspiro[3.3]heptane-1-carbonyl)-4-fluorophenyl]methyl]-2H-phthalazin-1-one
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|
C21H19FN4O2
|
1
|
| 1 |
IC50 = 526.1 nM
|
|
|
|
CP0519917
|
tert-butyl 6-[2-fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzoyl]-2,6-diazaspiro[3.3]heptane-2-carboxylate
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|
C26H27FN4O4
|
1
|
| 1 |
IC50 = 551.6 nM
|
|
|
|
CP0480657
|
tert-butyl 1-[2-fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzoyl]-1,6-diazaspiro[3.3]heptane-6-carboxylate
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|
C26H27FN4O4
|
1
|
| 1 |
IC50 = 877 nM
|
|
|
|
CP0389557
|
tert-butyl 2-[2-fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzoyl]-2,8-diazaspiro[4.5]decane-8-carboxylate
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|
C29H33FN4O4
|
1
|
| 1 |
IC50 = 1105 nM
|
|
|
|
CP0538789
|
4-[[3-(2,7-diazaspiro[4.4]nonane-2-carbonyl)-4-fluorophenyl]methyl]-2H-phthalazin-1-one
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|
C23H23FN4O2
|
1
|
| 1 |
IC50 = 1118 nM
|
|
|
|
CP0417455
|
tert-butyl 7-[2-fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzoyl]-2,7-diazaspiro[3.4]octane-2-carboxylate
Show/Hide
|
C27H29FN4O4
|
1
|
| 1 |
IC50 = 1193 nM
|
|
|
|
CP0481981
|
4-[[3-(2,6-diazaspiro[3.4]octane-6-carbonyl)-4-fluorophenyl]methyl]-2H-phthalazin-1-one
Show/Hide
|
C22H21FN4O2
|
1
|
| 1 |
IC50 = 1237 nM
|
|
|
|
CP0481991
|
4-[[3-(2,7-diazaspiro[3.5]nonane-2-carbonyl)-4-fluorophenyl]methyl]-2H-phthalazin-1-one
Show/Hide
|
C23H23FN4O2
|
1
|
| 1 |
IC50 = 1419 nM
|
|
|
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CP0518790
|
4-[[3-(2,6-diazaspiro[3.3]heptane-2-carbonyl)-4-fluorophenyl]methyl]-2H-phthalazin-1-one
Show/Hide
|
C21H19FN4O2
|
1
|
| 1 |
IC50 = 2395 nM
|
|
|
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CP0389553
|
4-[[3-[2-(cyclopropanecarbonyl)-2,7-diazaspiro[3.4]octane-7-carbonyl]-4-fluorophenyl]methyl]-2H-phthalazin-1-one
Show/Hide
|
C26H25FN4O3
|
1
|
| 1 |
IC50 = 2535 nM
|
|
|
|
CP0567887
|
4-[[3-[7-(cyclopropanecarbonyl)-2,7-diazaspiro[4.4]nonane-2-carbonyl]-4-fluorophenyl]methyl]-2H-phthalazin-1-one
Show/Hide
|
C27H27FN4O3
|
1
|
| 1 |
IC50 = 2586 nM
|
|
|
|
CP0530658
|
tert-butyl 1-[2-fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzoyl]-1,7-diazaspiro[3.5]nonane-7-carboxylate
Show/Hide
|
C28H31FN4O4
|
1
|
| 1 |
IC50 = 2969 nM
|
|
|
|
CP0474686
|
tert-butyl 2-[2-fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzoyl]-2,7-diazaspiro[3.5]nonane-7-carboxylate
Show/Hide
|
C28H31FN4O4
|
1
|
| 1 |
IC50 = 3118 nM
|
|
|
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CP0482831
|
4-[[3-(2,8-diazaspiro[4.5]decane-2-carbonyl)-4-fluorophenyl]methyl]-2H-phthalazin-1-one
Show/Hide
|
C24H25FN4O2
|
1
|
| 1 |
IC50 = 3881 nM
|
|
|
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CP0478961
|
tert-butyl 7-[2-fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzoyl]-2,7-diazaspiro[4.4]nonane-2-carboxylate
Show/Hide
|
C28H31FN4O4
|
1
|
| 1 |
IC50 = 4397 nM
|
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