General Information of the Cell Line
Cell Line ID
CL000549
Cell Line Name
Namalwa
Synonyms
NAMALWA
Namalwa IV
Namalva
NAMALVA
NWA
NK62a
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0067
Disease
EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01654, Tyrosine-protein kinase Blk
 Protein Info 
Compound ID Compound Name Compound Formula
CP0568167
 Compound Info 
N-[4-methyl-3-[[2-[3-[(1-prop-2-enoylpiperidin-4-yl)amino]anilino]pyrimidin-5-yl]carbamoyl]phenyl]isoquinoline-6-carboxamide
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C36H34N8O3
  1
1
IC50 = 5.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0550588
 Compound Info 
N-[3-[[2-[3-[[1-[(E)-4-(dimethylamino)but-2-enoyl]piperidin-4-yl]amino]anilino]pyrimidin-5-yl]carbamoyl]-4-methylphenyl]isoquinoline-6-carboxamide
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C39H41N9O3
  1
1
IC50 = 12 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0113747
 Compound Info 
2-methyl-N-[2-[3-(prop-2-enoylamino)anilino]pyrimidin-5-yl]-5-[[3-(trifluoromethyl)benzoyl]amino]benzamide
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C29H23F3N6O3
  1
1
IC50 = 15 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0550589
 Compound Info 
N-[4-methyl-3-[[2-[3-(prop-2-enoylamino)anilino]pyrimidin-5-yl]carbamoyl]phenyl]isoquinoline-6-carboxamide
   Show/Hide
C31H25N7O3
  1
1
IC50 = 63 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT01308, Tyrosine-protein kinase BTK
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0007430
 Compound Info 
IBRUTINIB
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 C25H24N6O2  1
1
GI50 = 6000 nM
   TI
   LI
   LO
   TS
CP0086121
 Compound Info 
ACP-196
   Show/Hide
 C26H23N7O2  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0383415
 Compound Info 
N-[2-methyl-5-(2-oxo-9-pyrazol-1-ylbenzo[h][1,6]naphthyridin-1-yl)phenyl]propanamide
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 C25H21N5O2  1
1
GI50 > 10000 nM
   TI
   LI
   LO
   TS
CP0405068
 Compound Info 
N-[3-[[5-fluoro-2-[4-methoxy-3-(3-morpholin-4-ylpropoxy)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
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 C27H31FN6O4  1
1
IC50 = 3170 nM
   TI
   LI
   LO
   TS
CP0405070
 Compound Info 
N-[3-[[5-chloro-2-[3-chloro-4-(2-morpholin-4-yl-2-oxoethoxy)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
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 C25H24Cl2N6O4  1
1
IC50 = 6450 nM
   TI
   LI
   LO
   TS
CP0438691
 Compound Info 
methyl 1-[2-[4-[[5-chloro-4-[3-(prop-2-enoylamino)anilino]pyrimidin-2-yl]amino]phenoxy]acetyl]pyrrolidine-2-carboxylate
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 C27H27ClN6O5  1
1
IC50 = 4800 nM
   TI
   LI
   LO
   TS
CP0457509
 Compound Info 
N-[3-[[5-chloro-2-[3-chloro-4-(3-morpholin-4-ylpropoxy)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
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 C26H28Cl2N6O3  1
1
IC50 = 19360 nM
   TI
   LI
   LO
   TS
CP0482354
 Compound Info 
N-[3-[[2-[4-[3-(4-ethylpiperazin-1-yl)propoxy]-2-methylanilino]-5-fluoropyrimidin-4-yl]amino]phenyl]prop-2-enamide
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 C29H36FN7O2  1
1
IC50 = 26630 nM
   TI
   LI
   LO
   TS
CP0513285
 Compound Info 
N-[3-[[5-chloro-2-[3-methoxy-4-(3-morpholin-4-ylpropoxy)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
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 C27H31ClN6O4  1
1
IC50 = 14400 nM
   TI
   LI
   LO
   TS
CP0968212
 Compound Info 
(E)-3-((5-((1H-benzo[d]imidazol-2-yl)thio)furan-2-yl)methylene)pyrrolidine-2,5-dione
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 C16H11N3O3S  1
1
IC50 > 50000 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line