| Compound ID |
Compound Name |
Compound Formula |
|
CP0178189
|
5-ethyl-3-[2-methoxyethyl(methyl)amino]-6-methyl-4-[(3-methylphenyl)methyl]-1H-pyridin-2-one
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|
C20H28N2O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0251262
|
(E)-3-[3-[[3-ethyl-5-[2-methoxyethyl(methyl)amino]-2-methyl-6-oxo-1H-pyridin-4-yl]methyl]phenyl]prop-2-enenitrile
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|
C22H27N3O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0251263
|
(E)-3-[3-[[3-ethyl-5-[ethyl(methyl)amino]-2-methyl-6-oxo-1H-pyridin-4-yl]methyl]phenyl]prop-2-enenitrile
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|
C21H25N3O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0146025
|
4-[(3,5-dimethylphenyl)methyl]-5-ethyl-3-[2-methoxyethyl(methyl)amino]-6-methyl-1H-pyridin-2-one
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|
C21H30N2O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0364326
|
5-ethyl-3-[3-hydroxypropyl(methyl)amino]-6-methyl-4-[(3-methylphenyl)methyl]-1H-pyridin-2-one
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|
C20H28N2O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0158455
|
2-[[5-ethyl-6-methyl-4-[(3-methylphenyl)methyl]-2-oxo-1H-pyridin-3-yl]-methylamino]acetonitrile
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|
C19H23N3O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0158457
|
4-[(3,5-dimethylphenyl)methyl]-5-ethyl-3-[5-hydroxypentyl(methyl)amino]-6-methyl-1H-pyridin-2-one
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|
C23H34N2O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0360268
|
4-[[5-ethyl-6-methyl-4-[(3-methylphenyl)methyl]-2-oxo-1H-pyridin-3-yl]-methylamino]butanenitrile
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|
C21H27N3O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0434512
|
5-ethyl-3-[2-hydroxyethyl(methyl)amino]-6-methyl-4-[(3-methylphenyl)methyl]-1H-pyridin-2-one
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|
C19H26N2O2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0146027
|
4-[(3,5-dimethylphenyl)methyl]-5-ethyl-3-[1-methoxypropan-2-yl(methyl)amino]-6-methyl-1H-pyridin-2-one
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|
C22H32N2O2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0159580
|
4-[(3,5-dimethylphenyl)methyl]-5-ethyl-3-[ethyl(methyl)amino]-6-methyl-1H-pyridin-2-one
Show/Hide
|
C20H28N2O
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0159581
|
4-[(3,5-dimethylphenyl)methyl]-5-ethyl-6-methyl-3-(methylamino)-1H-pyridin-2-one
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|
C18H24N2O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0251265
|
5-ethyl-3-[5-hydroxypentyl(methyl)amino]-6-methyl-4-[(3-methylphenyl)methyl]-1H-pyridin-2-one
Show/Hide
|
C22H32N2O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0158456
|
4-[(3,5-dimethylphenyl)methyl]-5-ethyl-6-methyl-3-pyrrol-1-yl-1H-pyridin-2-one
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|
C21H24N2O
|
1
|
| 1 |
IC50 = 12.6 nM
|
|
|
|
CP0360269
|
3-[2-ethoxyethyl(methyl)amino]-5-ethyl-6-methyl-4-[(3-methylphenyl)methyl]-1H-pyridin-2-one
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|
C21H30N2O2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0146024
|
4-[(3,5-dimethylphenyl)methyl]-5-ethyl-3-(ethylamino)-6-methyl-1H-pyridin-2-one
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|
C19H26N2O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0159579
|
4-[(3,5-dimethylphenyl)methyl]-5-ethyl-6-methyl-3-[methyl(propyl)amino]-1H-pyridin-2-one
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|
C21H30N2O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0251266
|
3-(diethylamino)-4-[(3,5-dimethylphenyl)methyl]-5-ethyl-6-methyl-1H-pyridin-2-one
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|
C21H30N2O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0262551
|
3-[[5-ethyl-6-methyl-4-[(3-methylphenyl)methyl]-2-oxo-1H-pyridin-3-yl]-methylamino]propanenitrile
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|
C20H25N3O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0153531
|
4-[(3,5-dimethylphenyl)methyl]-5-ethyl-6-methyl-3-(propylamino)-1H-pyridin-2-one
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|
C20H28N2O
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0158704
|
4-[(3,5-dimethylphenyl)methyl]-5-ethyl-6-methyl-3-[methyl(3-methylsulfanylpropyl)amino]-1H-pyridin-2-one
Show/Hide
|
C22H32N2OS
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0153532
|
4-(3,5-Dimethylbenzyl)-5-ethyl-3-formamido-6-methylpyridin-2(1H)-one
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|
C18H22N2O2
|
1
|
| 1 |
IC50 = 79 nM
|
|
|
|
CP0364329
|
3-(butylamino)-4-[(3,5-dimethylphenyl)methyl]-5-ethyl-6-methyl-1H-pyridin-2-one
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|
C21H30N2O
|
1
|
| 1 |
IC50 = 126 nM
|
|
|
|
CP0364328
|
4-[(3,5-dimethylphenyl)methyl]-5-ethyl-6-methyl-3-morpholin-4-yl-1H-pyridin-2-one
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|
C21H28N2O2
|
1
|
| 1 |
IC50 = 158 nM
|
|
|
|
CP0146023
|
3-(benzylamino)-4-[(3,5-dimethylphenyl)methyl]-5-ethyl-6-methyl-1H-pyridin-2-one
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|
C24H28N2O
|
1
|
| 1 |
IC50 = 251 nM
|
|
|
|
CP0484788
|
[5-ethyl-6-methyl-4-[(3-methylphenyl)methyl]-2-oxo-1H-pyridin-3-yl]thiourea
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|
C17H21N3OS
|
1
|
| 1 |
IC50 = 316 nM
|
|
|
|
CP0192708
|
N-[4-[(3,5-dimethylphenyl)methyl]-5-ethyl-6-methyl-2-oxo-1H-pyridin-3-yl]acetamide
Show/Hide
|
C19H24N2O2
|
1
|
| 1 |
IC50 = 398 nM
|
|
|
|
CP0158702
|
4-[(3,5-dimethylphenyl)methyl]-5-ethyl-6-methyl-3-piperidin-1-yl-1H-pyridin-2-one
Show/Hide
|
C22H30N2O
|
1
|
| 1 |
IC50 = 631 nM
|
|
|
|
CP0433936
|
1-[5-ethyl-6-methyl-4-[(3-methylphenyl)methyl]-2-oxo-1H-pyridin-3-yl]-3-phenylthiourea
Show/Hide
|
C23H25N3OS
|
1
|
| 1 |
IC50 = 3162 nM
|
|
|
|
CP0262552
|
N-[4-[(3,5-dimethylphenyl)methyl]-5-ethyl-6-methyl-2-oxo-1H-pyridin-3-yl]propanamide
Show/Hide
|
C20H26N2O2
|
1
|
| 1 |
IC50 = 3981 nM
|
|
|
|
CP0484790
|
1-ethyl-3-[5-ethyl-6-methyl-4-[(3-methylphenyl)methyl]-2-oxo-1H-pyridin-3-yl]thiourea
Show/Hide
|
C19H25N3OS
|
1
|
| 1 |
IC50 = 25119 nM
|
|
|
|
CP0082015
|
3-(dibutylamino)-4-[(3,5-dimethylphenyl)methyl]-5-ethyl-6-methyl-1H-pyridin-2-one
Show/Hide
|
C25H38N2O
|
1
|
| 1 |
IC50 = 50119 nM
|
|
|
|
CP0146022
|
3-(dibenzylamino)-4-[(3,5-dimethylphenyl)methyl]-5-ethyl-6-methyl-1H-pyridin-2-one
Show/Hide
|
C31H34N2O
|
1
|
| 1 |
IC50 = 100000 nM
|
|
|
|
CP0251267
|
N-[4-[(3,5-dimethylphenyl)methyl]-5-ethyl-6-methyl-2-oxo-1H-pyridin-3-yl]butanamide
Show/Hide
|
C21H28N2O2
|
1
|
| 1 |
IC50 = 100000 nM
|
|
|
