General Information of the Cell Line
Cell Line ID
CL000476
Cell Line Name
A2774
Synonyms
A-2774
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_U376
Disease
Ovarian serous adenocarcinoma (NCIt: C7550)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01058, Snake venom-like protease
 Protein Info 
Compound ID Compound Name Compound Formula
CP0062139
 Compound Info 
(R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(hydroxyamino)-4-oxobutylcarbamate
   Show/Hide
C22H25N3O7S
  2
1
IC50 = 26 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 419 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0132610
 Compound Info 
(2R)-5-(carbamoylamino)-2-[[4-[(3,5-dibromophenyl)methoxy]phenyl]sulfonylamino]-N-hydroxypentanamide
   Show/Hide
C19H22Br2N4O6S
  2
1
IC50 = 45 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 651 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0073959
 Compound Info 
benzyl N-[(4R)-4-[[4-[(3,5-dibromophenyl)methoxy]phenyl]sulfonylamino]-5-(hydroxyamino)-5-oxopentyl]carbamate
   Show/Hide
C26H27Br2N3O7S
  2
1
IC50 = 274 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 7626 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0109071
 Compound Info 
benzyl N-[(3R)-3-[[4-[(3,5-dibromophenyl)methoxy]phenyl]sulfonylamino]-4-(hydroxyamino)-4-oxobutyl]carbamate
   Show/Hide
C25H25Br2N3O7S
  2
1
IC50 = 1391 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0132603
 Compound Info 
2-[[4-[(3,5-dibromophenyl)methoxy]phenyl]sulfonylamino]-N-hydroxyacetamide
   Show/Hide
C15H14Br2N2O5S
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line