| Compound ID |
Compound Name |
Compound Formula |
|
CP0427768
|
6-[4-[2-(dimethylamino)ethoxy]phenyl]-N-(1,3-dithiolan-2-ylmethyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
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|
C26H29N5OS2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
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CP0044001
|
N-(1,3-dithiolan-2-ylmethyl)-5-phenyl-6-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
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|
C28H31N5OS2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
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CP0088957
|
6-[4-[2-(dimethylamino)ethoxy]phenyl]-N-(1,3-dithiolan-2-ylmethyl)-5-phenylfuro[2,3-d]pyrimidin-4-amine
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|
C26H28N4O2S2
|
1
|
| 1 |
IC50 = 10 nM
|
|
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CP0427769
|
6-[4-[2-(dimethylamino)ethoxy]phenyl]-N-[[(2S)-oxolan-2-yl]methyl]-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
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|
C27H31N5O2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
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CP0436198
|
N,N-dimethyl-4-[4-[[(2S)-oxolan-2-yl]methylamino]-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl]benzamide
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|
C26H27N5O2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
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CP0481030
|
1-[2-[4-[4-[[(2S)-oxolan-2-yl]methylamino]-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenoxy]ethyl]pyrrolidin-2-one
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|
C29H31N5O3
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0544604
|
morpholin-4-yl-[4-[4-[[(2S)-oxolan-2-yl]methylamino]-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl]methanone
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|
C28H29N5O3
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0200044
|
(S)-6-(4-(2-(dimethylamino)ethoxy)phenyl)-5-phenyl-N-((tetrahydrofuran-2-yl)methyl)furo[2,3-d]pyrimidin-4-amine
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|
C27H30N4O3
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
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CP0412467
|
N-methyl-4-[4-[[(2S)-oxolan-2-yl]methylamino]-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl]benzamide
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|
C25H25N5O2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0416244
|
5-(2-fluorophenyl)-N-[[(2S)-oxolan-2-yl]methyl]-6-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
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|
C29H32FN5O2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0494810
|
N-methyl-4-[4-[[(2S)-oxolan-2-yl]methylamino]-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl]benzenesulfonamide
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|
C24H25N5O3S
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0380624
|
N-[[(2S)-oxolan-2-yl]methyl]-5-phenyl-6-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Show/Hide
|
C29H33N5O2
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0488094
|
6-[4-(2-morpholin-4-ylethoxy)phenyl]-N-[[(2S)-oxolan-2-yl]methyl]-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
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|
C29H33N5O3
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
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CP0375828
|
N,N-dimethyl-4-[4-[[(2S)-oxolan-2-yl]methylamino]-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl]benzenesulfonamide
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|
C25H27N5O3S
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
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CP0375827
|
6-(4-methylsulfonylphenyl)-N-[[(2S)-oxolan-2-yl]methyl]-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
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|
C24H24N4O3S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0436123
|
6-[4-(2-morpholin-4-ylethoxy)phenyl]-N-[[(2S)-oxolan-2-yl]methyl]-5-phenylfuro[2,3-d]pyrimidin-4-amine
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|
C29H32N4O4
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
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CP0533374
|
5-(3-methoxyphenyl)-N-[[(2S)-oxolan-2-yl]methyl]-6-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
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|
C30H35N5O3
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
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CP0544601
|
5-(2-methylphenyl)-N-[[(2S)-oxolan-2-yl]methyl]-6-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Show/Hide
|
C30H35N5O2
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
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CP0544600
|
N,N-dimethyl-4-[4-[[(2S)-oxolan-2-yl]methylamino]-5-phenylfuro[2,3-d]pyrimidin-6-yl]benzamide
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|
C26H26N4O3
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
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CP0481031
|
morpholin-4-yl-[4-[4-[[(2S)-oxolan-2-yl]methylamino]-5-phenylfuro[2,3-d]pyrimidin-6-yl]phenyl]methanone
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|
C28H28N4O4
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
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CP0514810
|
1-[2-[4-[4-[[(2S)-oxolan-2-yl]methylamino]-5-phenylfuro[2,3-d]pyrimidin-6-yl]phenoxy]ethyl]pyrrolidin-2-one
Show/Hide
|
C29H30N4O4
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0540569
|
5-(cyclopenten-1-yl)-6-[4-[2-(dimethylamino)ethoxy]phenyl]-N-[[(2S)-oxolan-2-yl]methyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Show/Hide
|
C26H33N5O2
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
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CP0514809
|
6-(4-methylsulfonylphenyl)-N-[[(2S)-oxolan-2-yl]methyl]-5-phenylfuro[2,3-d]pyrimidin-4-amine
Show/Hide
|
C24H23N3O4S
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
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CP0436122
|
N-methyl-4-[4-[[(2S)-oxolan-2-yl]methylamino]-5-phenylfuro[2,3-d]pyrimidin-6-yl]benzenesulfonamide
Show/Hide
|
C24H24N4O4S
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
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CP0436121
|
6-(4-methoxyphenyl)-N-[[(2S)-oxolan-2-yl]methyl]-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Show/Hide
|
C24H24N4O2
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
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CP0507342
|
N-[[(2S)-oxolan-2-yl]methyl]-5-pyridin-3-yl-6-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Show/Hide
|
C28H32N6O2
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
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CP0544602
|
(1R,2S)-2-[[[6-[4-[2-(dimethylamino)ethoxy]phenyl]-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]methyl]cyclobutan-1-ol
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|
C27H31N5O2
|
1
|
| 1 |
IC50 = 410 nM
|
|
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CP0544605
|
6-[4-[2-(dimethylamino)ethoxy]phenyl]-N-[[(1S,2R)-2-methoxycyclobutyl]methyl]-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
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|
C28H33N5O2
|
1
|
| 1 |
IC50 = 420 nM
|
|
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CP0436125
|
(1R,2R)-2-[[[6-[4-[2-(dimethylamino)ethoxy]phenyl]-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]methyl]cyclopentan-1-ol
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|
C28H33N5O2
|
1
|
| 1 |
IC50 = 460 nM
|
|
|
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CP0424082
|
5-(cyclohexen-1-yl)-6-[4-[2-(dimethylamino)ethoxy]phenyl]-N-[[(2S)-oxolan-2-yl]methyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Show/Hide
|
C27H35N5O2
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
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CP0427773
|
6-[4-[2-(dimethylamino)ethoxy]phenyl]-N-(1,3-dithian-2-ylmethyl)-5-phenylfuro[2,3-d]pyrimidin-4-amine
Show/Hide
|
C27H30N4O2S2
|
1
|
| 1 |
IC50 = 550 nM
|
|
|
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CP0544603
|
6-(4-methoxyphenyl)-N-[[(2S)-oxolan-2-yl]methyl]-5-phenylfuro[2,3-d]pyrimidin-4-amine
Show/Hide
|
C24H23N3O3
|
1
|
| 1 |
IC50 = 550 nM
|
|
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CP0544599
|
N-[[(2S)-oxolan-2-yl]methyl]-5,6-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Show/Hide
|
C23H22N4O
|
1
|
| 1 |
IC50 = 620 nM
|
|
|
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CP0416245
|
6-[4-[2-(dimethylamino)ethoxy]phenyl]-N-[[(1R,2R)-2-methoxycyclopentyl]methyl]-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Show/Hide
|
C29H35N5O2
|
1
|
| 1 |
IC50 = 780 nM
|
|
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CP0494811
|
6-[4-[2-(dimethylamino)ethoxy]phenyl]-N-[[(1S,2R)-2-methoxycyclopentyl]methyl]-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Show/Hide
|
C29H35N5O2
|
1
|
| 1 |
IC50 = 1300 nM
|
|
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CP0436124
|
6-[4-[2-(dimethylamino)ethoxy]phenyl]-N-(1,3-dioxolan-2-ylmethyl)-5-phenylfuro[2,3-d]pyrimidin-4-amine
Show/Hide
|
C26H28N4O4
|
1
|
| 1 |
IC50 = 2000 nM
|
|
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CP0530374
|
N-methyl-4-[4-[[(2S)-oxolan-2-yl]methylamino]-5-phenylfuro[2,3-d]pyrimidin-6-yl]benzamide
Show/Hide
|
C25H24N4O3
|
1
|
| 1 |
IC50 = 2050 nM
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|
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CP0507343
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6-[4-[2-(dimethylamino)ethoxy]phenyl]-5-phenyl-N-(thiolan-2-ylmethyl)furo[2,3-d]pyrimidin-4-amine
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|
C27H30N4O2S
|
1
|
| 1 |
IC50 = 3000 nM
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|
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CP0344507
|
2,3-Diarylfuro[2,3-b]pyridine-4-amine, 6
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|
C24H22N2O2
|
1
|
| 1 |
IC50 = 5600 nM
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CP0375829
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6-[4-[2-(dimethylamino)ethoxy]phenyl]-5-phenyl-N-[[(2S)-thian-2-yl]methyl]furo[2,3-d]pyrimidin-4-amine
Show/Hide
|
C28H32N4O2S
|
1
|
| 1 |
IC50 = 7160 nM
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