Compound ID |
Compound Name |
Compound Formula |
CP0452663
|
4-(2-(cyclohexylamino)-6-(trifluoromethyl)pyrimidin-4-yl)benzenesulfonamide
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|
C17H19F3N4O2S
|
1
|
1 |
IC50 = 167 nM
|
|
|
CP0472128
|
4-(2-(butylamino)-6-(trifluoromethyl)pyrimidin-4-yl)benzenesulfonamide
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|
C15H17F3N4O2S
|
1
|
1 |
IC50 = 700 nM
|
|
|
CP0061060
|
5-Bromo-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-thiophene
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|
C17H12BrFO2S2
|
1
|
1 |
IC50 = 870 nM
|
|
|
CP0011191
|
4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide
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|
C17H14F3N3O2S
|
1
|
1 |
IC50 = 1689 nM
|
|
|
CP0469539
|
4-[2-(4-Fluoro-phenyl)-6-methoxy-pyrazolo[1,5-b]pyridazin-3-yl]-benzenesulfonamide
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|
C19H15FN4O3S
|
1
|
1 |
IC50 = 2605 nM
|
|
|
CP0457431
|
2-(cyclohexylmethyl)-4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)pyrimidine
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|
C24H25FN2O2S
|
1
|
1 |
IC50 = 2969 nM
|
|
|
CP0498487
|
4-[2-(4-Ethoxy-phenyl)-pyrazolo[1,5-b]pyridazin-3-yl]-benzenesulfonamide
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|
C20H18N4O3S
|
1
|
1 |
IC50 = 3828 nM
|
|
|
CP0451844
|
3-(4-Methanesulfonyl-phenyl)-2-(4-methoxy-phenyl)-pyrazolo[1,5-b]pyridazine
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|
C20H17N3O3S
|
1
|
1 |
IC50 = 3880 nM
|
|
|
CP0517116
|
4-(4-fluorophenyl)-N-methyl-5-(4-(methylsulfonyl)phenyl)-N-phenylpyrimidin-2-amine
Show/Hide
|
C24H20FN3O2S
|
1
|
1 |
IC50 = 4340 nM
|
|
|
CP0452661
|
N-cyclohexyl-4-(4-methylsulfonylphenyl)-6-(2,2,2-trifluoroethoxy)pyrimidin-2-amine
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|
C19H22F3N3O3S
|
1
|
1 |
IC50 = 6321 nM
|
|
|
CP0452666
|
4-(4-fluorophenyl)-2-((1-methyl-1H-pyrrol-2-yl)methyl)-5-(4-(methylsulfonyl)phenyl)pyrimidine
Show/Hide
|
C23H20FN3O2S
|
1
|
1 |
IC50 = 6541 nM
|
|
|
CP0497006
|
4-[2-(4-Ethoxy-phenyl)-6-methylsulfanyl-pyrazolo[1,5-b]pyridazin-3-yl]-benzenesulfonamide
Show/Hide
|
C21H20N4O3S2
|
1
|
1 |
IC50 = 8630 nM
|
|
|
CP0492582
|
4-(4-fluorophenyl)-2-isopropyl-5-(4-(methylsulfonyl)phenyl)pyrimidine
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|
C20H19FN2O2S
|
1
|
1 |
IC50 = 10000 nM
|
|
|
CP0404719
|
3-(4-Methanesulfonyl-phenyl)-2-p-tolyl-pyrazolo[1,5-b]pyridazine
Show/Hide
|
C20H17N3O2S
|
1
|
1 |
IC50 > 19100 nM
|
|
|
CP0404720
|
4-[2-(4-Fluoro-phenyl)-pyrazolo[1,5-b]pyridazin-3-yl]-benzenesulfonamide
Show/Hide
|
C18H13FN4O2S
|
1
|
1 |
IC50 = 24100 nM
|
|
|
CP0505880
|
4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)-2-phenethylpyrimidine
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|
C25H21FN2O2S
|
1
|
1 |
IC50 = 29371 nM
|
|
|
CP0097394
|
5-(4-Fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-3-trifluoromethyl-1H-pyrazole
Show/Hide
|
C17H12F4N2O2S
|
1
|
1 |
IC50 = 32000 nM
|
|
|
CP0492581
|
2-benzyl-4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)pyrimidine
Show/Hide
|
C24H19FN2O2S
|
1
|
1 |
IC50 > 34000 nM
|
|
|
CP0469538
|
2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-6-methoxy-pyrazolo[1,5-b]pyridazine
Show/Hide
|
C20H16FN3O3S
|
1
|
1 |
IC50 > 35100 nM
|
|
|
CP0496845
|
3-(4-Methanesulfonyl-phenyl)-6-methyl-2-phenyl-pyrazolo[1,5-b]pyridazine
Show/Hide
|
C20H17N3O2S
|
1
|
1 |
IC50 = 43900 nM
|
|
|
CP0455242
|
2-(2,4-difluorobenzyl)-4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)pyrimidine
Show/Hide
|
C24H17F3N2O2S
|
1
|
1 |
IC50 > 52124 nM
|
|
|
CP0497450
|
2-(3-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-pyrazolo[1,5-b]pyridazine
Show/Hide
|
C19H14FN3O2S
|
1
|
1 |
IC50 = 58300 nM
|
|
|
CP0492565
|
N-cyclohexyl-4-(4-methylsulfonylphenyl)-6-(trifluoromethyl)pyrimidin-2-amine
Show/Hide
|
C18H20F3N3O2S
|
1
|
1 |
IC50 > 58400 nM
|
|
|
CP0492572
|
N-(4-fluorophenyl)-4-(4-methylsulfonylphenyl)-6-(trifluoromethyl)pyrimidin-2-amine
Show/Hide
|
C18H13F4N3O2S
|
1
|
1 |
IC50 > 65800 nM
|
|
|
CP0396906
|
N-butan-2-yl-4-(4-methylsulfonylphenyl)-6-(trifluoromethyl)pyrimidin-2-amine
Show/Hide
|
C16H18F3N3O2S
|
1
|
1 |
IC50 > 66200 nM
|
|
|
CP0485346
|
N-methyl-N-(4-methylphenyl)-4-(4-methylsulfonylphenyl)-6-(trifluoromethyl)pyrimidin-2-amine
Show/Hide
|
C20H18F3N3O2S
|
1
|
1 |
IC50 > 74175 nM
|
|
|
CP0392520
|
2-(4-Ethoxy-phenyl)-3-(4-methanesulfonyl-phenyl)-pyrazolo[1,5-b]pyridazine
Show/Hide
|
C21H19N3O3S
|
1
|
1 |
IC50 > 84200 nM
|
|
|
CP0485347
|
4-(4-(methylsulfonyl)phenyl)-N-(tetrahydro-2H-pyran-4-yl)-6-(trifluoromethyl)pyrimidin-2-amine
Show/Hide
|
C17H18F3N3O3S
|
1
|
1 |
IC50 > 91629 nM
|
|
|
CP0037144
|
4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one
Show/Hide
|
C17H14O4S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0040447
|
4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzene-1-sulfonamide
Show/Hide
|
C16H14N2O3S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0132427
|
5-Chloro-3-(4-methanesulfonyl-phenyl)-6''-methyl-[2,3'']bipyridinyl
Show/Hide
|
C18H15ClN2O2S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0430083
|
6-Ethyl-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-pyrazolo[1,5-b]pyridazine
Show/Hide
|
C21H18FN3O2S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0451843
|
3-(4-Methanesulfonyl-phenyl)-2-phenyl-pyrazolo[1,5-b]pyridazine
Show/Hide
|
C19H15N3O2S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0469542
|
6-Ethoxy-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-pyrazolo[1,5-b]pyridazine
Show/Hide
|
C21H18FN3O3S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0469546
|
2-(4-Fluoro-phenyl)-6-isopropoxy-3-(4-methanesulfonyl-phenyl)-pyrazolo[1,5-b]pyridazine
Show/Hide
|
C22H20FN3O3S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0496838
|
2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-6-methyl-pyrazolo[1,5-b]pyridazine
Show/Hide
|
C20H16FN3O2S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0496865
|
2-(4-Fluoro-phenyl)-6-methanesulfonyl-3-(4-methanesulfonyl-phenyl)-pyrazolo[1,5-b]pyridazine
Show/Hide
|
C20H16FN3O4S2
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0496866
|
4-[2-(4-Ethoxy-phenyl)-6-methanesulfonyl-pyrazolo[1,5-b]pyridazin-3-yl]-benzenesulfonamide
Show/Hide
|
C21H20N4O5S2
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0497959
|
2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-pyrazolo[1,5-b]pyridazine
Show/Hide
|
C19H14FN3O2S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0498492
|
3-(4-Methanesulfonyl-phenyl)-6-methoxy-2-p-tolyl-pyrazolo[1,5-b]pyridazine
Show/Hide
|
C21H19N3O3S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0500754
|
4-[2-(4-Trifluoromethoxy-phenyl)-pyrazolo[1,5-b]pyridazin-3-yl]-benzenesulfonamide
Show/Hide
|
C19H13F3N4O3S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0428840
|
2-N-cyclohexyl-6-(4-methylsulfonylphenyl)pyrimidine-2,4-diamine
Show/Hide
|
C17H22N4O2S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0428841
|
4-(4-(methylsulfonyl)phenyl)-N-(piperidin-4-yl)-6-(trifluoromethyl)pyrimidin-2-amine
Show/Hide
|
C17H19F3N4O2S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0452662
|
4-Trifluoromethyl-13-thia-5,7,19-triaza-tricyclo[12.2.2.1*2,6*]nonadeca-1(17),2,4,6(19),14(18),15-hexaene 13,13-dioxide
Show/Hide
|
C16H16F3N3O2S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0452664
|
N-butyl-4-(4-methylsulfonylphenyl)-6-(trifluoromethyl)pyrimidin-2-amine
Show/Hide
|
C16H18F3N3O2S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0452665
|
N-benzyl-4-(4-methylsulfonylphenyl)-6-(trifluoromethyl)pyrimidin-2-amine
Show/Hide
|
C19H16F3N3O2S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0457428
|
4-(4-(methylsulfonyl)phenyl)-N-((tetrahydro-2H-pyran-4-yl)methyl)-6-(trifluoromethyl)pyrimidin-2-amine
Show/Hide
|
C18H20F3N3O3S
|
1
|
1 |
IC50 = 100000 nM
|
|
|
CP0457429
|
N-(cyclohexylmethyl)-4-(4-methylsulfonylphenyl)-6-(trifluoromethyl)pyrimidin-2-amine
Show/Hide
|
C19H22F3N3O2S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0457430
|
N-[(4-methylphenyl)methyl]-4-(4-methylsulfonylphenyl)-6-(trifluoromethyl)pyrimidin-2-amine
Show/Hide
|
C20H18F3N3O2S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0472127
|
2-(cyclohexylamino)-6-(4-(methylsulfonyl)phenyl)pyrimidine-4-carboxylic acid
Show/Hide
|
C18H21N3O4S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0485344
|
2-(cyclohexylamino)-6-(4-(methylsulfonyl)phenyl)pyrimidine-4-carboxamide
Show/Hide
|
C18H22N4O3S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0485345
|
N-cyclohexyl-5-methyl-4-(4-methylsulfonylphenyl)-6-(trifluoromethyl)pyrimidin-2-amine
Show/Hide
|
C19H22F3N3O2S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0492566
|
4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidin-2-amine
Show/Hide
|
C12H10F3N3O2S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0492568
|
N-[(4-fluorophenyl)methyl]-4-(4-methylsulfonylphenyl)-6-(trifluoromethyl)pyrimidin-2-amine
Show/Hide
|
C19H15F4N3O2S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0504274
|
N-cyclohexyl-4-methyl-6-(4-methylsulfonylphenyl)pyrimidin-2-amine
Show/Hide
|
C18H23N3O2S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0509353
|
N-cyclohexyl-4-(4-methylsulfonylphenyl)pyrimidin-2-amine
Show/Hide
|
C17H21N3O2S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0509354
|
N-cyclohexyl-5-methyl-4-(4-methylsulfonylphenyl)pyrimidin-2-amine
Show/Hide
|
C18H23N3O2S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0509358
|
4-(4-(methylsulfonyl)phenyl)-N-phenyl-6-(trifluoromethyl)pyrimidin-2-amine
Show/Hide
|
C18H14F3N3O2S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0524034
|
4-(4-(methylsulfonyl)phenyl)-N-propyl-6-(trifluoromethyl)pyrimidin-2-amine
Show/Hide
|
C15H16F3N3O2S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0524035
|
4-(4-(methylsulfonyl)phenyl)-N-p-tolyl-6-(trifluoromethyl)pyrimidin-2-amine
Show/Hide
|
C19H16F3N3O2S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0422086
|
2-(4-fluorobenzyl)-4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)pyrimidine
Show/Hide
|
C24H18F2N2O2S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0422087
|
4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)-2-(phenylthio)pyrimidine
Show/Hide
|
C23H17FN2O2S2
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0422091
|
4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)-2-phenoxypyrimidine
Show/Hide
|
C23H17FN2O3S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0473841
|
N-benzyl-4-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)pyrimidin-2-amine
Show/Hide
|
C24H20FN3O2S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0492579
|
4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)-N-phenylpyrimidin-2-amine
Show/Hide
|
C23H18FN3O2S
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0502249
|
4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)-2-(pyridin-2-ylmethyl)pyrimidine
Show/Hide
|
C23H18FN3O2S
|
1
|
1 |
IC50 > 100000 nM
|
|
|