(6S,7S)-6-ethyl-7-methyl-4-(trifluoromethyl)-6,7,8,9-tetrahydropyrano[3,2-g]quinolin-2-one

5-Ethyl-4-trifluoromethyl-5,6,7,8-tetrahydro-1-oxa-8-aza-anthracen-2-one

7,7-Dimethyl-4-trifluoromethyl-5,6,7,8-tetrahydro-1-oxa-8-aza-anthracen-2-one

8-ethyl-4-(trifluoromethyl)-6,7,8,9-tetrahydropyrano[3,2-g]quinolin-2-one

5-Methyl-4-trifluoromethyl-5,6,7,8-tetrahydro-1-oxa-8-aza-anthracen-2-one

4-Trifluoromethyl-5,6,7,8-tetrahydro-1-oxa-8-aza-anthracen-2-one

5-(2-chloro-4-hydroxyphenyl)-1-methylpyrrole-2-carbonitrile

5-(2,6-difluoro-4-hydroxyphenyl)-1-methylpyrrole-2-carbonitrile

4,5-Bis-trifluoromethyl-5,6,7,8-tetrahydro-1-oxa-8-aza-anthracen-2-one

(6R,7S)-6-ethyl-7-methyl-4-(trifluoromethyl)-6,7,8,9-tetrahydropyrano[3,2-g]quinolin-2-one

1-[(2S)-3-(4-bromophenoxy)-2-hydroxy-2-methylpropanoyl]-2,3-dihydroindole-4-carbonitrile

5-(4-hydroxy-3-methylphenyl)-1-methylpyrrole-2-carbonitrile

1-[(2S)-3-(4-cyano-2-fluorophenoxy)-2-hydroxy-2-methylpropanoyl]-2,3-dihydroindole-4-carbonitrile

5-(2-fluoro-4-hydroxyphenyl)-1-methylpyrrole-2-carbonitrile

1-[(2S)-3-(2-chloro-4-methoxyphenoxy)-2-hydroxy-2-methylpropanoyl]-2,3-dihydroindole-4-carbonitrile

5-(4-hydroxy-2-methylphenyl)-1-methylpyrrole-2-carbonitrile

(1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-5-one

1-[(2S)-3-(2-bromo-4-cyanophenoxy)-2-hydroxy-2-methylpropanoyl]-2,3-dihydroindole-4-carbonitrile

5-(4-hydroxy-2,3-dimethylphenyl)-1-methylpyrrole-2-carbonitrile

5-Propyl-4-trifluoromethyl-5,6,7,8-tetrahydro-1-oxa-8-aza-anthracen-2-one

5-Pentafluoroethyl-4-trifluoromethyl-5,6,7,8-tetrahydro-1-oxa-8-aza-anthracen-2-one

1-[(2S)-3-(4-chloro-2-fluorophenoxy)-2-hydroxy-2-methylpropanoyl]-2,3-dihydroindole-4-carbonitrile

5-(4-hydroxyphenyl)-1-methylpyrrole-2-carbonitrile

5-(2-cyano-4-hydroxyphenyl)-1-methylpyrrole-2-carbonitrile

7-Ethyl-6-methyl-4-trifluoromethyl-5,6,7,8-tetrahydro-1-oxa-8-aza-anthracen-2-one

6,8-diethyl-4-(trifluoromethyl)-6,7,8,9-tetrahydropyrano[3,2-g]quinolin-2-one

5-(3-ethyl-4-hydroxyphenyl)-1-methylpyrrole-2-carbonitrile

5-(7-hydroxy-2,3-dihydro-1H-inden-4-yl)-1-methylpyrrole-2-carbonitrile

1-[(2S)-3-(2-cyano-4-fluorophenoxy)-2-hydroxy-2-methylpropanoyl]-2,3-dihydroindole-4-carbonitrile

1-[(2S)-3-(2,4-dichlorophenoxy)-2-hydroxy-2-methylpropanoyl]-2,3-dihydroindole-4-carbonitrile

1-[(2S)-3-(2-fluorophenoxy)-2-hydroxy-2-methylpropanoyl]-2,3-dihydroindole-4-carbonitrile

1-[(2S)-3-(4-fluoro-2-methylphenoxy)-2-hydroxy-2-methylpropanoyl]-2,3-dihydroindole-4-carbonitrile

8-ethyl-6-methyl-4-(trifluoromethyl)-6,7,8,9-tetrahydropyrano[3,2-g]quinolin-2-one

5-(4-hydroxyphenyl)-1-methyl-3-(trifluoromethyl)pyrrole-2-carbonitrile

1-[(2S)-3-(2-bromo-4-fluorophenoxy)-2-hydroxy-2-methylpropanoyl]-2,3-dihydroindole-4-carbonitrile

(6S,8R)-6-ethyl-8-methyl-4-(trifluoromethyl)-6,7,8,9-tetrahydropyrano[3,2-g]quinolin-2-one

1-[(2S)-3-(4-fluorophenoxy)-2-hydroxy-2-methylpropanoyl]-2,3-dihydroindole-4-carbonitrile

1-[(2S)-3-(2-cyanophenoxy)-2-hydroxy-2-methylpropanoyl]-2,3-dihydroindole-4-carbonitrile

5-[4-hydroxy-2-(trifluoromethyl)phenyl]-1-methylpyrrole-2-carbonitrile

1-[(2S)-3-(4-cyano-2-methoxyphenoxy)-2-hydroxy-2-methylpropanoyl]-2,3-dihydroindole-4-carbonitrile

1-[(2S)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanoyl]-2,3-dihydroindole-4-carbonitrile

5-(2,6-dichloro-4-hydroxyphenyl)-1-methylpyrrole-2-carbonitrile

1-[(2S)-2-hydroxy-2-methyl-3-[4-(trifluoromethyl)phenoxy]propanoyl]-2,3-dihydroindole-4-carbonitrile

1-[(2S)-3-(3-fluorophenoxy)-2-hydroxy-2-methylpropanoyl]-2,3-dihydroindole-4-carbonitrile

1-[(2S)-3-(4-chlorophenoxy)-2-hydroxy-2-methylpropanoyl]-2,3-dihydroindole-4-carbonitrile

1-[(2S)-3-(4-bromo-2-fluorophenoxy)-2-hydroxy-2-methylpropanoyl]-2,3-dihydroindole-4-carbonitrile

5-(2,3-difluoro-4-hydroxyphenyl)-1-methylpyrrole-2-carbonitrile

(2S)-3-(4-cyanopyrazol-1-yl)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide

5-(3-chloro-4-hydroxyphenyl)-1-methylpyrrole-2-carbonitrile

1-[(2S)-3-(2-chlorophenoxy)-2-hydroxy-2-methylpropanoyl]-2,3-dihydroindole-4-carbonitrile

5-(3-fluoro-4-hydroxyphenyl)-1-methylpyrrole-2-carbonitrile

1-[(2S)-2-hydroxy-2-methyl-3-[2-(trifluoromethyl)phenoxy]propanoyl]-2,3-dihydroindole-4-carbonitrile

US10806720, Compound 1022

5-(4-hydroxy-2-nitrophenyl)-1-methylpyrrole-2-carbonitrile

5-(2-cyano-6-fluoro-4-hydroxyphenyl)-1-methylpyrrole-2-carbonitrile

US10806720, Compound 1058

5-(2,5-difluoro-4-hydroxyphenyl)-1-methylpyrrole-2-carbonitrile

1-[(2S)-2-hydroxy-2-methyl-3-phenoxypropanoyl]-2,3-dihydroindole-4-carbonitrile

1-[(2S)-3-(3-chlorophenoxy)-2-hydroxy-2-methylpropanoyl]-2,3-dihydroindole-4-carbonitrile

Bicalutamide

1-ethyl-5-(2-fluoro-4-hydroxyphenyl)pyrrole-2-carbonitrile

methyl 4-[(2S)-3-(4-cyano-2,3-dihydroindol-1-yl)-2-hydroxy-2-methyl-3-oxopropoxy]benzoate

1-[(2S)-2-hydroxy-3-(4-methoxyphenoxy)-2-methylpropanoyl]-2,3-dihydroindole-4-carbonitrile

4-bromo-5-(4-hydroxyphenyl)-1-methylpyrrole-2-carbonitrile

1-[(2S)-2-hydroxy-2-methyl-3-[4-(1,3-oxazol-4-yl)phenoxy]propanoyl]-2,3-dihydroindole-4-carbonitrile

US10806720, Compound 1002

5-Ethyl-8-methyl-4-trifluoromethyl-5,6,7,8-tetrahydro-1-oxa-8-aza-anthracen-2-one

methyl 2-(5-cyano-1-methylpyrrol-2-yl)-5-hydroxybenzoate

1-[(2S)-3-(4-chloro-2-methoxyphenoxy)-2-hydroxy-2-methylpropanoyl]-2,3-dihydroindole-4-carbonitrile

1-[(2S)-3-(2-fluoro-4-methoxyphenoxy)-2-hydroxy-2-methylpropanoyl]-2,3-dihydroindole-4-carbonitrile

5-(4-hydroxy-2-methylsulfonylphenyl)-1-methylpyrrole-2-carbonitrile

1-(cyanomethyl)-5-(2-fluoro-4-hydroxyphenyl)pyrrole-2-carbonitrile

2-[2-cyano-5-(2-fluoro-4-hydroxyphenyl)pyrrol-1-yl]acetic acid

(5bR,9aR)-1-Methyl-4-trifluoromethyl-1,5b,6,7,8,9,9a,10-octahydro-pyrido[2,3-b]carbazol-2-one

(5bR,9aR)-4-Trifluoromethyl-1,5b,6,7,8,9,9a,10-octahydro-pyrido[2,3-b]carbazol-2-one

(2R,3R)-2,3-Dimethyl-5-trifluoromethyl-1,2,3,8-tetrahydro-pyrrolo[3,2-g]quinolin-7-one

(R)-2,8-Dimethyl-5-trifluoromethyl-1,2,3,8-tetrahydro-pyrrolo[3,2-g]quinolin-7-one

(5bR,9aR)-1,5b-Dimethyl-4-trifluoromethyl-1,5b,6,7,8,9,9a,10-octahydro-pyrido[2,3-b]carbazol-2-one

(R)-2,3,3,8-Tetramethyl-5-trifluoromethyl-1,2,3,8-tetrahydro-pyrrolo[3,2-g]quinolin-7-one

(5bR,9aR)-1,10-Dimethyl-4-trifluoromethyl-1,5b,6,7,8,9,9a,10-octahydro-pyrido[2,3-b]carbazol-2-one

(2R,3R)-2,3,8-Trimethyl-5-trifluoromethyl-1,2,3,8-tetrahydro-pyrrolo[3,2-g]quinolin-7-one

(R)-2-Methyl-5-trifluoromethyl-1,2,3,8-tetrahydro-pyrrolo[3,2-g]quinolin-7-one

(S)-3-Methyl-5-trifluoromethyl-1,2,3,8-tetrahydro-pyrrolo[3,2-g]quinolin-7-one

(R)-2,3,3-Trimethyl-5-trifluoromethyl-1,2,3,8-tetrahydro-pyrrolo[3,2-g]quinolin-7-one

(5bR,9aR)-5b-Methyl-4-trifluoromethyl-1,5b,6,7,8,9,9a,10-octahydro-pyrido[2,3-b]carbazol-2-one

(5bR,7S,9aR)-7-Methyl-4-trifluoromethyl-1,5b,6,7,8,9,9a,10-octahydro-pyrido[2,3-b]carbazol-2-one

3,3-Dimethyl-5-trifluoromethyl-1,2,3,8-tetrahydro-pyrrolo[3,2-g]quinolin-7-one

(R)-1,2,3,3,8-Pentamethyl-5-trifluoromethyl-1,2,3,8-tetrahydro-pyrrolo[3,2-g]quinolin-7-one

5-Trifluoromethyl-1,2,3,8-tetrahydro-pyrrolo[3,2-g]quinolin-7-one

(5bR,9aS)-1,9,9,10-Tetramethyl-4-trifluoromethyl-1,5b,6,7,8,9,9a,10-octahydro-pyrido[2,3-b]carbazol-2-one

8-Methyl-5-trifluoromethyl-1,2,3,8-tetrahydro-pyrrolo[3,2-g]quinolin-7-one

(5bR,9aR)-1-Methyl-10-propyl-4-trifluoromethyl-1,5b,6,7,8,9,9a,10-octahydro-pyrido[2,3-b]carbazol-2-one

(5bR,9aR)-5b,9,9-Trimethyl-4-trifluoromethyl-1,5b,6,7,8,9,9a,10-octahydro-pyrido[2,3-b]carbazol-2-one

(5bR,7S,9aR)-1,7,10-Trimethyl-4-trifluoromethyl-1,5b,6,7,8,9,9a,10-octahydro-pyrido[2,3-b]carbazol-2-one

(5bR,9aS)-9,9-Dimethyl-4-trifluoromethyl-1,5b,6,7,8,9,9a,10-octahydro-pyrido[2,3-b]carbazol-2-one

(5bR,7S,9aR)-1,7-Dimethyl-4-trifluoromethyl-1,5b,6,7,8,9,9a,10-octahydro-pyrido[2,3-b]carbazol-2-one

(5bR,9aR)-1,5b,10-Trimethyl-4-trifluoromethyl-1,5b,6,7,8,9,9a,10-octahydro-pyrido[2,3-b]carbazol-2-one

1,8-Dimethyl-5-trifluoromethyl-1,2,3,8-tetrahydro-pyrrolo[3,2-g]quinolin-7-one

(5bR,9aR)-1-Ethyl-4-trifluoromethyl-1,5b,6,7,8,9,9a,10-octahydro-pyrido[2,3-b]carbazol-2-one