| Compound ID |
Compound Name |
Compound Formula |
|
CP0228854
|
4-(4-cyclopentylpiperazin-1-yl)-6-methoxy-2-(4-methylpiperazin-1-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazoline
Show/Hide
|
C30H47N7O2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0243980
|
[4-[2-(dimethylamino)-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-yl]piperazin-1-yl]-phenylmethanone
Show/Hide
|
C29H38N6O3
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0365488
|
4-(4-cyclopentylpiperazin-1-yl)-6-methoxy-N,N-dimethyl-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-2-amine
Show/Hide
|
C27H42N6O2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0422349
|
6-methoxy-N,N-dimethyl-4-piperazin-1-yl-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-2-amine
Show/Hide
|
C22H34N6O2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0228855
|
4-(4-cyclopentylpiperazin-1-yl)-6-methoxy-N-[3-(4-methylpiperazin-1-yl)propyl]-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-2-amine
Show/Hide
|
C33H54N8O2
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0365489
|
[4-(aminomethyl)phenyl]-[4-[2-(dimethylamino)-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-yl]piperazin-1-yl]methanone
Show/Hide
|
C30H41N7O3
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0434988
|
[4-[2-(dimethylamino)-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-yl]piperazin-1-yl]-(4-fluorophenyl)methanone
Show/Hide
|
C29H37FN6O3
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0476443
|
6-methoxy-4-(4-methylpiperazin-1-yl)-N-[3-(4-methylpiperazin-1-yl)propyl]-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-2-amine
Show/Hide
|
C29H48N8O2
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0513268
|
4-[4-(cyclopentylmethyl)piperazin-1-yl]-6-methoxy-N,N-dimethyl-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-2-amine
Show/Hide
|
C28H44N6O2
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0392596
|
6-methoxy-N,N-dimethyl-4-(4-methylpiperazin-1-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-2-amine
Show/Hide
|
C23H36N6O2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0426350
|
4-(4-cyclopentylpiperazin-1-yl)-N-[(4-fluorophenyl)methyl]-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-2-amine
Show/Hide
|
C32H43FN6O2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0457733
|
4-(4-cyclopentylpiperazin-1-yl)-N-(3-imidazol-1-ylpropyl)-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-2-amine
Show/Hide
|
C31H46N8O2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0558204
|
7-cyclopentyloxy-6-methoxy-N,N-dimethyl-4-(4-methylpiperazin-1-yl)quinazolin-2-amine
Show/Hide
|
C21H31N5O2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0514111
|
4-(4-benzylpiperazin-1-yl)-6-methoxy-N,N-dimethyl-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-2-amine
Show/Hide
|
C29H40N6O2
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0351216
|
7-cyclopentyloxy-6-methoxy-N,N-dimethyl-4-piperazin-1-ylquinazolin-2-amine
Show/Hide
|
C20H29N5O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0076708
|
CHEBI:5801
Show/Hide
|
C18H26ClN3O
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0513270
|
1-[4-[2-(dimethylamino)-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-yl]piperazin-1-yl]-2-methylpropan-1-one
Show/Hide
|
C26H40N6O3
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0365487
|
6-methoxy-N,N-dimethyl-7-phenylmethoxy-4-piperazin-1-ylquinazolin-2-amine
Show/Hide
|
C22H27N5O2
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0526911
|
2-(3,4-dimethoxyphenyl)-3-methyl-5-[1-[(2-methyl-1H-imidazol-5-yl)methyl]piperidin-4-yl]-1H-indole
Show/Hide
|
C27H32N4O2
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0426349
|
4-(4-cyclopentylpiperazin-1-yl)-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazoline
Show/Hide
|
C25H37N5O2
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0530751
|
2-(3,4-dimethoxyphenyl)-3-methyl-5-[1-(1-methylpiperidin-4-yl)piperidin-4-yl]-1H-indole
Show/Hide
|
C28H37N3O2
|
1
|
| 1 |
IC50 = 216 nM
|
|
|
|
CP0411533
|
6-methoxy-N,N-dimethyl-4-(4-propan-2-ylsulfonylpiperazin-1-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-2-amine
Show/Hide
|
C25H40N6O4S
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0176609
|
6-methoxy-N,N-dimethyl-4-(4-methylpiperazin-1-yl)-7-phenylmethoxyquinazolin-2-amine
Show/Hide
|
C23H29N5O2
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0479712
|
2-(3,4-dimethoxyphenyl)-5-[1-[2-(methylamino)ethyl]piperidin-4-yl]-1H-indole-3-carbonitrile
Show/Hide
|
C25H30N4O2
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0564267
|
4-[3-methyl-5-[1-[2-(methylamino)ethyl]piperidin-4-yl]-1H-indol-2-yl]benzamide
Show/Hide
|
C24H30N4O
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0388427
|
2-[4-[2-(3,4-dimethoxyphenyl)-3-methyl-1H-indol-5-yl]piperidin-1-yl]-N-methylethanamine
Show/Hide
|
C25H33N3O2
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0564656
|
2-[4-[3-chloro-2-(3,4-dimethoxyphenyl)-1H-indol-5-yl]piperidin-1-yl]-N-methylethanamine
Show/Hide
|
C24H30ClN3O2
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0539157
|
3-[3-methyl-5-[1-[2-(methylamino)ethyl]piperidin-4-yl]-1H-indol-2-yl]benzonitrile
Show/Hide
|
C24H28N4
|
1
|
| 1 |
IC50 = 460 nM
|
|
|
|
CP0540175
|
2-[4-[2-(3,4-dimethoxyphenyl)-3-ethyl-1H-indol-5-yl]piperidin-1-yl]-N-methylethanamine
Show/Hide
|
C26H35N3O2
|
1
|
| 1 |
IC50 = 490 nM
|
|
|
|
CP0537435
|
cyclopentyl-[4-[2-(dimethylamino)-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-yl]piperazin-1-yl]methanone
Show/Hide
|
C28H42N6O3
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0539158
|
2-[4-[2-(4-methoxyphenyl)-3-methyl-1H-indol-5-yl]piperidin-1-yl]-N-methylethanamine
Show/Hide
|
C24H31N3O
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0520907
|
4-[3-methyl-5-[1-[2-(methylamino)ethyl]piperidin-4-yl]-1H-indol-2-yl]benzonitrile
Show/Hide
|
C24H28N4
|
1
|
| 1 |
IC50 = 520 nM
|
|
|
|
CP0511285
|
3-[4-[2-(3,4-dimethoxyphenyl)-3-methyl-1H-indol-5-yl]piperidin-1-yl]-N-methylpropan-1-amine
Show/Hide
|
C26H35N3O2
|
1
|
| 1 |
IC50 = 550 nM
|
|
|
|
CP0532207
|
2-[3-methyl-5-[1-[2-(methylamino)ethyl]piperidin-4-yl]-1H-indol-2-yl]benzonitrile
Show/Hide
|
C24H28N4
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0388424
|
2-[4-[2-(3,4-dimethoxyphenyl)-3-propan-2-yl-1H-indol-5-yl]piperidin-1-yl]-N-methylethanamine
Show/Hide
|
C27H37N3O2
|
2
|
| 1 |
IC50 = 700 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
|
CP0530758
|
2-[4-[2-(3,4-dimethoxyphenyl)-1,3-dimethylindol-5-yl]piperidin-1-yl]-N-methylethanamine
Show/Hide
|
C26H35N3O2
|
1
|
| 1 |
IC50 = 740 nM
|
|
|
|
CP0930996
|
2-(3,4-Dimethoxyphenyl)-3-methyl-5-(1-((1-methylpiperidin-2-yl)methyl)piperidin-4-yl)-1H-indole
Show/Hide
|
C29H39N3O2
|
1
|
| 1 |
IC50 = 740 nM
|
|
|
|
CP0526910
|
2-[4-[2-(3,4-dimethoxyphenyl)-3-(2,2,2-trifluoroethyl)-1H-indol-5-yl]piperidin-1-yl]-N-methylethanamine
Show/Hide
|
C26H32F3N3O2
|
1
|
| 1 |
IC50 = 750 nM
|
|
|
|
CP0940052
|
2-(4-(2-(3,4-Dimethoxyphenyl)-3-isobutyl-1H-indol-5-yl)piperidin-1-yl)-N-methylethanamine
Show/Hide
|
C28H39N3O2
|
1
|
| 1 |
IC50 = 830 nM
|
|
|
|
CP0564281
|
2-(3,4-dimethoxyphenyl)-3-methyl-5-[1-[(1-methylimidazol-2-yl)methyl]piperidin-4-yl]-1H-indole
Show/Hide
|
C27H32N4O2
|
1
|
| 1 |
IC50 = 850 nM
|
|
|
|
CP0520908
|
2-[4-[2-(2-methoxyphenyl)-3-methyl-1H-indol-5-yl]piperidin-1-yl]-N-methylethanamine
Show/Hide
|
C24H31N3O
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0388430
|
2-[4-[2-(1,3-benzodioxol-5-yl)-3-methyl-1H-indol-5-yl]piperidin-1-yl]-N-methylethanamine
Show/Hide
|
C24H29N3O2
|
1
|
| 1 |
IC50 = 1205 nM
|
|
|
|
CP0479713
|
2-[4-[2-(3-ethoxy-4-propan-2-yloxyphenyl)-3-methyl-1H-indol-5-yl]piperidin-1-yl]-N-methylethanamine
Show/Hide
|
C28H39N3O2
|
1
|
| 1 |
IC50 = 1660 nM
|
|
|
|
CP0520906
|
N-methyl-2-[4-(3-methyl-2-phenyl-1H-indol-5-yl)piperidin-1-yl]ethanamine
Show/Hide
|
C23H29N3
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0540174
|
2-[4-[2-(3-methoxyphenyl)-3-methyl-1H-indol-5-yl]piperidin-1-yl]-N-methylethanamine
Show/Hide
|
C24H31N3O
|
1
|
| 1 |
IC50 = 1870 nM
|
|
|
|
CP0520909
|
N-methyl-2-[4-[3-methyl-2-(2-methylphenyl)-1H-indol-5-yl]piperidin-1-yl]ethanamine
Show/Hide
|
C24H31N3
|
1
|
| 1 |
IC50 = 2140 nM
|
|
|
|
CP0511286
|
2-[4-[2-(2,3-dimethoxyphenyl)-3-methyl-1H-indol-5-yl]piperidin-1-yl]-N-methylethanamine
Show/Hide
|
C25H33N3O2
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0511287
|
2-[4-[2-(2,4-dimethoxyphenyl)-3-methyl-1H-indol-5-yl]piperidin-1-yl]-N-methylethanamine
Show/Hide
|
C25H33N3O2
|
1
|
| 1 |
IC50 = 2330 nM
|
|
|
|
CP0516548
|
5-[1-(azetidin-3-yl)piperidin-4-yl]-2-(3,4-dimethoxyphenyl)-3-methyl-1H-indole
Show/Hide
|
C25H31N3O2
|
1
|
| 1 |
IC50 = 2340 nM
|
|
|
|
CP0530757
|
N-methyl-2-[4-[3-methyl-2-(3-methylphenyl)-1H-indol-5-yl]piperidin-1-yl]ethanamine
Show/Hide
|
C24H31N3
|
1
|
| 1 |
IC50 = 2620 nM
|
|
|
|
CP0553104
|
2-(3,4-dimethoxyphenyl)-3-methyl-5-[1-[(3-methylimidazol-4-yl)methyl]piperidin-4-yl]-1H-indole
Show/Hide
|
C27H32N4O2
|
1
|
| 1 |
IC50 = 2710 nM
|
|
|
|
CP0532075
|
2-(3,4-dimethoxyphenyl)-3-methyl-5-[1-(pyridin-4-ylmethyl)piperidin-4-yl]-1H-indole
Show/Hide
|
C28H31N3O2
|
1
|
| 1 |
IC50 = 3360 nM
|
|
|
|
CP0513269
|
7-cyclopentyloxy-6-methoxy-N,N-dimethyl-4-piperidin-1-ylquinazolin-2-amine
Show/Hide
|
C21H30N4O2
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0558205
|
1-[4-[7-cyclopentyloxy-2-(dimethylamino)-6-methoxyquinazolin-4-yl]piperazin-1-yl]-2-methylpropan-1-one
Show/Hide
|
C24H35N5O3
|
1
|
| 1 |
IC50 = 4800 nM
|
|
|
|
CP0540177
|
2-(3,4-dimethoxyphenyl)-3-methyl-5-piperidin-4-yl-1H-indole
Show/Hide
|
C22H26N2O2
|
1
|
| 1 |
IC50 = 4845 nM
|
|
|
|
CP0218647
|
[4-[7-cyclopentyloxy-2-(dimethylamino)-6-methoxyquinazolin-4-yl]piperazin-1-yl]-phenylmethanone
Show/Hide
|
C27H33N5O3
|
1
|
| 1 |
IC50 = 5000 nM
|
|
|
|
CP0520905
|
N-methyl-2-[4-[3-methyl-2-(4-methylphenyl)-1H-indol-5-yl]piperidin-1-yl]ethanamine
Show/Hide
|
C24H31N3
|
1
|
| 1 |
IC50 = 5390 nM
|
|
|
|
CP0392408
|
4-[7-cyclopentyloxy-2-(dimethylamino)-6-methoxyquinazolin-4-yl]-N,N-dimethylpiperazine-1-carboxamide
Show/Hide
|
C23H34N6O3
|
1
|
| 1 |
IC50 = 5500 nM
|
|
|
|
CP0440121
|
[4-[2-(dimethylamino)-6-methoxy-7-phenylmethoxyquinazolin-4-yl]piperazin-1-yl]-phenylmethanone
Show/Hide
|
C29H31N5O3
|
1
|
| 1 |
IC50 = 9400 nM
|
|
|
|
CP0432289
|
4-[2-(dimethylamino)-6-methoxy-7-phenylmethoxyquinazolin-4-yl]-N,N-dimethylpiperazine-1-sulfonamide
Show/Hide
|
C24H32N6O4S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0438124
|
tert-butyl 4-[6-methoxy-2-(4-methylpiperazin-1-yl)-7-phenylmethoxyquinazolin-4-yl]piperazine-1-carboxylate
Show/Hide
|
C30H40N6O4
|
1
|
| 1 |
IC50 = 10200 nM
|
|
|
|
CP0514109
|
tert-butyl 4-[6-methoxy-2-[(4-methoxyphenyl)methylamino]-7-phenylmethoxyquinazolin-4-yl]piperazine-1-carboxylate
Show/Hide
|
C33H39N5O5
|
1
|
| 1 |
IC50 = 17000 nM
|
|
|
|
CP0466655
|
tert-butyl 4-[2-(dimethylamino)-6-methoxy-7-phenylmethoxyquinazolin-4-yl]piperazine-1-carboxylate
Show/Hide
|
C27H35N5O4
|
1
|
| 1 |
IC50 = 18000 nM
|
|
|
|
CP0520910
|
2-[4-[2-(2-chlorophenyl)-3-fluoro-1H-indol-5-yl]piperidin-1-yl]-N-methylethanamine
Show/Hide
|
C22H25ClFN3
|
1
|
| 1 |
IC50 = 21700 nM
|
|
|
|
CP0148104
|
2-[4-[3-fluoro-2-(2-methoxyphenyl)-1H-indol-5-yl]piperidin-1-yl]-N-methylethanamine
Show/Hide
|
C23H28FN3O
|
1
|
| 1 |
IC50 = 23300 nM
|
|
|
|
CP0513267
|
tert-butyl 4-[2-[(2-hydroxy-2-methylpropyl)amino]-6-methoxy-7-phenylmethoxyquinazolin-4-yl]piperazine-1-carboxylate
Show/Hide
|
C29H39N5O5
|
1
|
| 1 |
IC50 = 28000 nM
|
|
|
|
CP0478945
|
tert-butyl 4-(7-hydroxy-6-methoxyquinazolin-4-yl)piperazine-1-carboxylate
Show/Hide
|
C18H24N4O4
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0558639
|
1-[4-[2-(3,4-dimethoxyphenyl)-3-methyl-1H-indol-5-yl]piperidin-1-yl]ethanone
Show/Hide
|
C24H28N2O3
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0466656
|
tert-butyl 4-[2-(dimethylamino)-7-hydroxy-6-methoxyquinazolin-4-yl]piperazine-1-carboxylate
Show/Hide
|
C20H29N5O4
|
1
|
| 1 |
IC50 = 51000 nM
|
|
|
