Brief Information of the Cell Line and Protein
Cell Line ID: CL000861 , FL5.12
 Cell Line Info 
Synonyms
FL5.12A
Fetal Liver clone 5.12
Category Factor-dependent cell line
Organism
Mus musculus (Mouse)
Protein ID: PT00845 , RAC-alpha serine/threonine-protein kinase
 Protein Info 
Gene Name AKT1
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P31749
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000861
 Cell Line Info 
 Protein ID: PT00845
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0096607
 Compound Info 
6-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridin-3-yl}isoquinolin-3-amine
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C25H23N5O
  1
1
IC50 = 200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0099138
 Compound Info 
(2S)-1-(1H-indol-3-yl)-3-(5-isoquinolin-6-ylpyridin-3-yl)oxy-propan-2-amine
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C25H22N4O
  1
1
IC50 = 420 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0156191
 Compound Info 
6-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]-2-ethynylpyridin-3-yl}isoquinoline
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C27H22N4O
  1
1
IC50 = 1700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0099158
 Compound Info 
6-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridin-3-yl}-3-fluoroisoquinoline
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C25H21FN4O
  1
1
IC50 = 2300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0099159
 Compound Info 
6-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]-2-chloropyridin-3-yl}isoquinoline
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C25H21ClN4O
  1
1
IC50 = 5700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS