Brief Information of the Cell Line and Protein
Cell Line ID: CL000686 , HEK-Blue hTLR7
Synonyms
HEK-blue-HTLR7
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_IM84
Protein ID: PT02546 , Toll-like receptor 8
Gene Name TLR8
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID Q9NR97
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000686  Protein ID: PT02546
 
Compound ID Compound Name Compound Formula
CP0500234
6-(4-ethylpiperazin-1-yl)-N-[(4-methoxyphenyl)methyl]-9-(3-pyrrolidin-1-ylpropyl)purin-2-amine
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C26H38N8O
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0550019
6-(4-cyclopentylpiperazin-1-yl)-N-[(4-fluorophenyl)methyl]-9-(3-pyrrolidin-1-ylpropyl)purin-2-amine
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C28H39FN8
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0568719
6-(4-ethylpiperazin-1-yl)-N-[(4-fluorophenyl)methyl]-9-(3-pyrrolidin-1-ylpropyl)purin-2-amine
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C25H35FN8
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0569059
N-[6-(4-cyclopentylpiperazin-1-yl)-9-[3-(4-ethylpiperazin-1-yl)propyl]purin-2-yl]-4-[(dimethylamino)methyl]benzamide
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C33H50N10O
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS