Brief Information of the Cell Line and Protein
Cell Line ID: CL000460 , Flp-In-T-REx-293
 Cell Line Info 
Synonyms
Flp-In-T-REx 293
Flp-In T-REx-293
Flp-In T-REx 293
Flp-In T-Rex HEK293
Flp-In 293 T-Rex
Flp-In-T-REx
293-Flip-in-TRex
HEK293 Flp-In T-REx
HEK293FlpIN
293FlpIn T-Rex
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_U427
Protein ID: PT01312 , Metabotropic glutamate receptor 3
 Protein Info 
Gene Name GRM3
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID Q14832
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000460
 Cell Line Info 
 Protein ID: PT01312
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0458064
 Compound Info 
3-(cyclopropylmethyl)-7-[[4-(2,4-difluorophenyl)piperidin-1-yl]methyl]-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine
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C23H23F5N4
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0544956
 Compound Info 
7-[[4-(2-chloro-4-fluorophenyl)piperazin-1-yl]methyl]-3-(cyclopropylmethyl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine
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C22H22ClF4N5
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0544958
 Compound Info 
3-(cyclopropylmethyl)-7-[[4-(2-fluorophenyl)piperazin-1-yl]methyl]-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine
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C22H23F4N5
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0544959
 Compound Info 
3-(cyclopropylmethyl)-8-[[4-(2,4-difluorophenyl)piperazin-1-yl]methyl]-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine
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C22H22F5N5
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0568919
 Compound Info 
7-[[4-(4-chloro-2-fluorophenyl)piperazin-1-yl]methyl]-3-(cyclopropylmethyl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine
   Show/Hide
C22H22ClF4N5
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0568137
 Compound Info 
[1-(cyclopropylmethyl)-4-(trifluoromethyl)pyrazolo[3,4-b]pyridin-5-yl]-[4-(2,4-difluorophenyl)piperazin-1-yl]methanone
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C22H20F5N5O
  1
1
EC50 > 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0046845
 Compound Info 
3-(cyclopropylmethyl)-7-[[4-(2,4-difluorophenyl)piperazin-1-yl]methyl]-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine
   Show/Hide
C22H22F5N5
  1
1
EC50 > 8000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS