| Compound ID |
Compound Name |
Compound Formula |
|
CP0473714
|
2-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol-2-yl)isonicotinonitrile
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|
C21H14F2N4
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0235801
|
2-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol-2-yl)pyrazine
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|
C19H14F2N4
|
2
|
| 1 |
IC50 = 2.4 nM
|
|
|
| 2 |
IC50 = 4.3 nM
|
|
|
|
CP0474883
|
3-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol-2-yl)benzonitrile
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|
C22H15F2N3
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0431387
|
4,4-bis(4-fluorophenyl)-2-(3-nitrophenyl)-4,5-dihydro-1H-imidazole
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|
C21H15F2N3O2
|
1
|
| 1 |
IC50 = 4.3 nM
|
|
|
|
CP0431385
|
2-(3-bromophenyl)-4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazole
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|
C21H15BrF2N2
|
1
|
| 1 |
IC50 = 4.8 nM
|
|
|
|
CP0522779
|
4-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol-2-yl)picolinonitrile
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|
C21H14F2N4
|
1
|
| 1 |
IC50 = 4.8 nM
|
|
|
|
CP0423644
|
2-(3-chlorophenyl)-4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazole
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|
C21H15ClF2N2
|
1
|
| 1 |
IC50 = 5.4 nM
|
|
|
|
CP0527011
|
4,4-bis(4-fluorophenyl)-2-(3-(trifluoromethyl)phenyl)-4,5-dihydro-1H-imidazole
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|
C22H15F5N2
|
1
|
| 1 |
IC50 = 6.2 nM
|
|
|
|
CP0493798
|
3-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol-2-yl)pyridine
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|
C20H15F2N3
|
1
|
| 1 |
IC50 = 7.2 nM
|
|
|
|
CP0522550
|
6-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol-2-yl)pyridin-2(1H)-one
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|
C20H15F2N3O
|
1
|
| 1 |
IC50 = 8.1 nM
|
|
|
|
CP0529535
|
3-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol-2-yl)benzaldehyde
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|
C22H16F2N2O
|
1
|
| 1 |
IC50 = 8.7 nM
|
|
|
|
CP0497894
|
4,4-bis(4-fluorophenyl)-2-(3-(methylsulfonyl)phenyl)-4,5-dihydro-1H-imidazole
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|
C22H18F2N2O2S
|
1
|
| 1 |
IC50 = 9.2 nM
|
|
|
|
CP0481540
|
2-(3-fluorophenyl)-4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazole
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|
C21H15F3N2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0386285
|
5-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol-2-yl)nicotinonitrile
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|
C21H14F2N4
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0386282
|
4,4-bis(4-fluorophenyl)-2-m-tolyl-4,5-dihydro-1H-imidazole
Show/Hide
|
C22H18F2N2
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0431384
|
4,4-bis(4-fluorophenyl)-2-phenyl-4,5-dihydro-1H-imidazole
Show/Hide
|
C21H16F2N2
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0481541
|
6-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol-2-yl)picolinonitrile
Show/Hide
|
C21H14F2N4
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0398585
|
1-(3-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol-2-yl)phenyl)ethanone
Show/Hide
|
C23H18F2N2O
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0528398
|
5-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol-2-yl)pyrimidine
Show/Hide
|
C19H14F2N4
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0386283
|
4,4-bis(4-fluorophenyl)-2-(3-methoxyphenyl)-4,5-dihydro-1H-imidazole
Show/Hide
|
C22H18F2N2O
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0431388
|
4,4-bis(4-fluorophenyl)-2-(thiophen-2-yl)-4,5-dihydro-1H-imidazole
Show/Hide
|
C19H14F2N2S
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
|
CP0455876
|
2,4,4-triphenylimidazoline
Show/Hide
|
C21H18N2
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
|
CP0474884
|
(3-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol-2-yl)phenyl)methanol
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|
C22H18F2N2O
|
1
|
| 1 |
IC50 = 59 nM
|
|
|
|
CP0474885
|
4,4-bis(4-fluorophenyl)-2-(thiophen-3-yl)-4,5-dihydro-1H-imidazole
Show/Hide
|
C19H14F2N2S
|
1
|
| 1 |
IC50 = 93 nM
|
|
|
|
CP0481539
|
2-(4-chlorophenyl)-4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazole
Show/Hide
|
C21H15ClF2N2
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0467607
|
4,4-bis(4-fluorophenyl)-2-(4-(trifluoromethyl)phenyl)-4,5-dihydro-1H-imidazole
Show/Hide
|
C22H15F5N2
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0509986
|
2-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol-2-yl)pyridine
Show/Hide
|
C20H15F2N3
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0511545
|
4-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol-2-yl)pyridine
Show/Hide
|
C20H15F2N3
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0526791
|
methyl 3-[5,5-bis(4-fluorophenyl)-1,4-dihydroimidazol-2-yl]benzoate
Show/Hide
|
C23H18F2N2O2
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0526792
|
3-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol-2-yl)aniline
Show/Hide
|
C21H17F2N3
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0386284
|
2-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol-2-yl)pyrimidine
Show/Hide
|
C19H14F2N4
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0509987
|
3-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol-2-yl)pyridazine
Show/Hide
|
C19H14F2N4
|
1
|
| 1 |
IC50 = 560 nM
|
|
|
|
CP0511544
|
2-(2-chlorophenyl)-4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazole
Show/Hide
|
C21H15ClF2N2
|
1
|
| 1 |
IC50 = 630 nM
|
|
|
|
CP0497879
|
3-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol-2-yl)-N,N-dimethylaniline
Show/Hide
|
C23H21F2N3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0528099
|
2-(7-chloro-2,3-dihydro-1,4-benzothiazin-4-yl)-N-[4-[(propan-2-ylsulfonylamino)methyl]cyclohexyl]acetamide
Show/Hide
|
C20H30ClN3O3S2
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0501614
|
2-(7-chloro-3-oxo-1,4-benzothiazin-4-yl)-N-[4-[(propan-2-ylsulfonylamino)methyl]cyclohexyl]acetamide
Show/Hide
|
C20H28ClN3O4S2
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0478542
|
CHEMBL1829326
Show/Hide
|
C21H32ClN3O3S
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0073407
|
2-(7-chloro-3-oxo-1,4-benzoxazin-4-yl)-N-[4-[(propan-2-ylsulfonylamino)methyl]cyclohexyl]acetamide
Show/Hide
|
C20H28ClN3O5S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0494714
|
2-(7-chloro-1,1-dioxo-2,3-dihydro-1lambda6,4-benzothiazin-4-yl)-N-[4-[(propan-2-ylsulfonylamino)methyl]cyclohexyl]acetamide
Show/Hide
|
C20H30ClN3O5S2
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0150743
|
2-(6-chloro-2-oxo-3,4-dihydroquinolin-1-yl)-N-[4-[(propan-2-ylsulfonylamino)methyl]cyclohexyl]acetamide
Show/Hide
|
C21H30ClN3O4S
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0150742
|
2-(7-chloro-2,3-dihydro-1,4-benzoxazin-4-yl)-N-[4-[(propan-2-ylsulfonylamino)methyl]cyclohexyl]acetamide
Show/Hide
|
C20H30ClN3O4S
|
1
|
| 1 |
Ki = 3.5 nM
|
|
|
|
CP0478545
|
N-[[4-[2-(6-chloro-3,4-dihydro-2H-quinolin-1-yl)ethylamino]cyclohexyl]methyl]propane-2-sulfonamide
Show/Hide
|
C21H34ClN3O2S
|
1
|
| 1 |
Ki = 4.4 nM
|
|
|
|
CP0508693
|
CHEMBL1829315
Show/Hide
|
C23H37N3O3S2
|
1
|
| 1 |
Ki = 6.9 nM
|
|
|
|
CP0472483
|
CHEMBL1829319
Show/Hide
|
C20H28FN3O5S
|
1
|
| 1 |
Ki = 8.4 nM
|
|
|
|
CP0509381
|
N-[[4-[2-[7-(trifluoromethyl)-2,3-dihydro-1,4-benzoxazin-4-yl]ethylamino]cyclohexyl]methyl]propane-2-sulfonamide
Show/Hide
|
C21H32F3N3O3S
|
1
|
| 1 |
Ki = 9.2 nM
|
|
|
|
CP0879964
|
9'-(6-Hydroxy-8-oxospiro[3.5]non-7-yl)-4',9'-dihydrospiro[cyclobutane-1,3'-xanthen]-1'(2'H)-one
Show/Hide
|
C25H26O4
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0919380
|
(9S)-9-(2-Hydroxy-4,4-dimethyl-6-oxo-1-cyclohexen-1-yl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one
Show/Hide
|
C23H26O4
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0466016
|
CHEMBL1829331
Show/Hide
|
C20H32ClN3O3S
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0879963
|
9'-(7-Hydroxy-9-oxospiro[4.5]dec-8-yl)-4',9'-dihydrospiro[cyclopentane-1,3'-xanthen]-1'(2'H)-one
Show/Hide
|
C27H30O4
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0504541
|
2-(2,2-dimethyl-4-oxo-3H-1,5-benzothiazepin-5-yl)-N-[4-[(propan-2-ylsulfonylamino)methyl]cyclohexyl]acetamide
Show/Hide
|
C23H35N3O4S2
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0926196
|
9-(4,4-Diethyl-2-hydroxy-6-oxocyclohexyl)-3,3-diethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one
Show/Hide
|
C27H34O4
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0502532
|
CHEMBL1829317
Show/Hide
|
C20H29N3O5S
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0501611
|
2-(2,2-dimethyl-1,1-dioxo-3,4-dihydro-1lambda6,5-benzothiazepin-5-yl)-N-[4-[(propan-2-ylsulfonylamino)methyl]cyclohexyl]acetamide
Show/Hide
|
C23H37N3O5S2
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0916038
|
9'-(2-Hydroxy-4-oxospiro[5.5]undec-3-yl)-4',9'-dihydrospiro[cyclohexane-1,3'-xanthen]-1'(2'H)-one
Show/Hide
|
C29H34O4
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0512479
|
2-(2,2-dimethyl-4-oxo-3H-1,5-benzothiazepin-5-yl)-N-[4-[(dimethylsulfamoylamino)methyl]cyclohexyl]acetamide
Show/Hide
|
C22H34N4O4S2
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0926509
|
6-Fluoro-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one
Show/Hide
|
C23H25FO4
|
1
|
| 1 |
Ki = 29 nM
|
|
|
|
CP0659250
|
9-(2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-enyl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one
Show/Hide
|
C23H26O4
|
1
|
| 1 |
Ki = 33 nM
|
|
|
|
CP0906863
|
6-Chloro-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one
Show/Hide
|
C23H25ClO4
|
1
|
| 1 |
Ki = 34 nM
|
|
|
|
CP0926508
|
5-Fluoro-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one
Show/Hide
|
C23H25FO4
|
1
|
| 1 |
Ki = 34 nM
|
|
|
|
CP0915023
|
6-Bromo-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one
Show/Hide
|
C23H25BrO4
|
1
|
| 1 |
Ki = 36 nM
|
|
|
|
CP0949784
|
9-(2-Hydroxy-4,4-dimethyl-6-oxocyclohexyl)-3,3,6-trimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one
Show/Hide
|
C24H28O4
|
1
|
| 1 |
Ki = 36 nM
|
|
|
|
CP0921350
|
6-Ethyl-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one
Show/Hide
|
C25H30O4
|
1
|
| 1 |
Ki = 41 nM
|
|
|
|
CP0503343
|
N-[[4-[2-(6-chloro-2,3-dihydro-1,4-benzoxazin-4-yl)ethylamino]cyclohexyl]methyl]propane-2-sulfonamide
Show/Hide
|
C20H32ClN3O3S
|
1
|
| 1 |
Ki = 60 nM
|
|
|
|
CP0879966
|
5-Chloro-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one
Show/Hide
|
C23H25ClO4
|
1
|
| 1 |
Ki = 71 nM
|
|
|
|
CP0873043
|
7-Fluoro-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one
Show/Hide
|
C23H25FO4
|
1
|
| 1 |
Ki = 81 nM
|
|
|
|
CP0526602
|
CHEMBL1829329
Show/Hide
|
C21H35N3O4S
|
1
|
| 1 |
Ki = 88 nM
|
|
|
|
CP0852108
|
9-(2-Hydroxy-4,4-dimethyl-6-oxocyclohexyl)-6-methoxy-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one
Show/Hide
|
C24H28O5
|
1
|
| 1 |
Ki = 93 nM
|
|
|
|
CP0494713
|
CHEMBL1829318
Show/Hide
|
C20H28FN3O5S
|
1
|
| 1 |
Ki = 97 nM
|
|
|
|
CP0504399
|
CHEMBL1829328
Show/Hide
|
C20H31F2N3O3S
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0509380
|
N-[[4-[2-(6-fluoro-2,3-dihydro-1,4-benzoxazin-4-yl)ethylamino]cyclohexyl]methyl]propane-2-sulfonamide
Show/Hide
|
C20H32FN3O3S
|
1
|
| 1 |
Ki = 170 nM
|
|
|
|
CP0915022
|
9-(2-Hydroxy-4-methyl-6-oxocyclohexyl)-3-methyl-2,3,4,9-tetrahydro-1H-xanthen-1-one
Show/Hide
|
C21H22O4
|
1
|
| 1 |
Ki = 193 nM
|
|
|
|
CP0873044
|
7-Chloro-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one
Show/Hide
|
C23H25ClO4
|
1
|
| 1 |
Ki = 197 nM
|
|
|
|
CP0438235
|
CHEMBL1829312
Show/Hide
|
C22H33N3O4S2
|
1
|
| 1 |
Ki = 200 nM
|
|
|
|
CP0466014
|
N-[4-[(cyclopropylsulfonylamino)methyl]cyclohexyl]-2-(2,2-dimethyl-4-oxo-3H-1,5-benzothiazepin-5-yl)acetamide
Show/Hide
|
C23H33N3O4S2
|
1
|
| 1 |
Ki = 210 nM
|
|
|
|
CP0917054
|
(9R)-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-enyl)-3,3-dimethyl-2,3,4,4a,9,9a-hexahydroxanthen-1-one
Show/Hide
|
C23H26O4
|
1
|
| 1 |
Ki = 343 nM
|
|
|
|
CP0389964
|
N-[[4-[2-(7-chloro-2,3-dihydro-1,4-benzothiazin-4-yl)ethylamino]cyclohexyl]methyl]propane-2-sulfonamide
Show/Hide
|
C20H32ClN3O2S2
|
1
|
| 1 |
Ki = 370 nM
|
|
|
|
CP0494712
|
N-[4-[(dimethylsulfamoylamino)methyl]cyclohexyl]-2-(4-oxo-2,3-dihydro-1,5-benzothiazepin-5-yl)acetamide
Show/Hide
|
C20H30N4O4S2
|
1
|
| 1 |
Ki = 420 nM
|
|
|
|
CP0919379
|
SID14729320
Show/Hide
|
C24H28O5
|
1
|
| 1 |
Ki = 590 nM
|
|
|
|
CP0844989
|
6-Ethoxy-9-(2-hydroxy-4,4-dimethyl-6-oxocyclohexyl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one
Show/Hide
|
C25H30O5
|
1
|
| 1 |
Ki = 833 nM
|
|
|
|
CP0509379
|
CHEMBL1829311
Show/Hide
|
C21H31N3O4S2
|
1
|
| 1 |
Ki = 1900 nM
|
|
|
|
CP0917053
|
9-(2-Hydroxy-4,4-dimethyl-6-oxocyclohexyl)-5-methoxy-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one
Show/Hide
|
C24H28O5
|
1
|
| 1 |
Ki = 2167 nM
|
|
|
|
CP0879965
|
SID7973801
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C19H18O4
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1
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| 1 |
Ki > 1000 nM
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CP0919494
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9-(2-Hydroxy-4,4-dimethyl-6-oxocyclohexyl)-8-methoxy-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one
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C24H28O5
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1
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| 1 |
Ki > 1000 nM
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