| Compound ID |
Compound Name |
Compound Formula |
|
CP0275533
|
(R)-2-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile
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|
C24H26N2O2
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0172829
|
(R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile
Show/Hide
|
C24H25ClN2O2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0500652
|
(S)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile
Show/Hide
|
C24H25ClN2O2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0562109
|
(S)-2-(3-(1-(benzo[b]thiophen-2-yl)-2-methylpropan-2-ylamino)-2-hydroxypropoxy)benzonitrile
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|
C22H24N2O2S
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0456467
|
(S)-2-(3-(1-(1H-indol-2-yl)-2-methylpropan-2-ylamino)-2-hydroxypropoxy)benzonitrile
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|
C22H25N3O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0436577
|
(R)-1-((R)-1-(3-nitrobenzyl)pyrrolidin-2-yl)-2-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)ethanol
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|
C27H33N3O3
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0494604
|
2-fluoro-6-(((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)ethyl)pyrrolidin-1-yl)methyl)phenol
Show/Hide
|
C27H33FN2O2
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0497419
|
2-(((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)ethyl)pyrrolidin-1-yl)methyl)-6-nitrophenol
Show/Hide
|
C27H33N3O4
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0432511
|
(R)-1-((R)-1-(2-nitrobenzyl)pyrrolidin-2-yl)-2-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)ethanol
Show/Hide
|
C27H33N3O3
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0442534
|
3-(((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)ethyl)pyrrolidin-1-yl)methyl)benzonitrile
Show/Hide
|
C28H33N3O
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0436595
|
2-chloro-6-(((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)ethyl)pyrrolidin-1-yl)methyl)benzonitrile
Show/Hide
|
C28H32ClN3O
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0523115
|
4-(((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)ethyl)pyrrolidin-1-yl)methyl)benzonitrile
Show/Hide
|
C28H33N3O
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0432510
|
3-(((R)-2-((R)-2-(1-(benzo[b]thiophen-2-yl)-2-methylpropan-2-ylamino)-1-hydroxyethyl)pyrrolidin-1-yl)methyl)benzonitrile
Show/Hide
|
C26H31N3OS
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0497420
|
(R)-2-chloro-6-(2-hydroxy-3-(methyl(2-methyl-1-(naphthalen-2-yl)propan-2-yl)amino)propoxy)benzonitrile
Show/Hide
|
C25H27ClN2O2
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0403301
|
2-(((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)ethyl)pyrrolidin-1-yl)methyl)benzonitrile
Show/Hide
|
C28H33N3O
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0403299
|
(R)-1-((R)-1-(2,3-difluorobenzyl)pyrrolidin-2-yl)-2-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)ethanol
Show/Hide
|
C27H32F2N2O
|
1
|
| 1 |
IC50 = 360 nM
|
|
|
|
CP0449584
|
3-(((R)-2-((R)-2-(1-(1H-indol-2-yl)-2-methylpropan-2-ylamino)-1-hydroxyethyl)pyrrolidin-1-yl)methyl)benzonitrile
Show/Hide
|
C26H32N4O
|
1
|
| 1 |
IC50 = 440 nM
|
|
|
|
CP0442530
|
(R)-2-chloro-6-(3-(1-(4-fluorophenyl)-2-methylpropan-2-ylamino)-2-hydroxypropoxy)benzonitrile
Show/Hide
|
C20H22ClFN2O2
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0442440
|
(R)-1-((R)-1-(3-fluorobenzyl)pyrrolidin-2-yl)-2-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)ethanol
Show/Hide
|
C27H33FN2O
|
1
|
| 1 |
IC50 = 750 nM
|
|
|
|
CP0436576
|
(R)-1-((R)-1-(4-nitrobenzyl)pyrrolidin-2-yl)-2-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)ethanol
Show/Hide
|
C27H33N3O3
|
1
|
| 1 |
IC50 = 790 nM
|
|
|
|
CP0442441
|
2-chloro-6-(3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile
Show/Hide
|
C24H25ClN2O
|
1
|
| 1 |
IC50 = 880 nM
|
|
|
|
CP0506522
|
2-(((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)ethyl)pyrrolidin-1-yl)methyl)phenol
Show/Hide
|
C27H34N2O2
|
1
|
| 1 |
IC50 = 970 nM
|
|
|
|
CP0442526
|
3-(((R)-2-((R)-2-(1-(benzo[b]thiophen-3-yl)-2-methylpropan-2-ylamino)-1-hydroxyethyl)pyrrolidin-1-yl)methyl)benzonitrile
Show/Hide
|
C26H31N3OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0449585
|
3-(((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)ethyl)pyrrolidin-1-yl)methyl)phenol
Show/Hide
|
C27H34N2O2
|
1
|
| 1 |
IC50 = 1160 nM
|
|
|
|
CP0442529
|
(R)-1-((R)-1-(3-methoxybenzyl)pyrrolidin-2-yl)-2-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)ethanol
Show/Hide
|
C28H36N2O2
|
1
|
| 1 |
IC50 = 1190 nM
|
|
|
|
CP0506523
|
2-(((R)-2-((S)-1-hydroxy-2-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)ethyl)pyrrolidin-1-yl)methyl)benzonitrile
Show/Hide
|
C28H33N3O
|
1
|
| 1 |
IC50 = 1270 nM
|
|
|
|
CP0500647
|
3-(((R)-2-((R)-2-(1-(benzo[d]thiazol-2-yl)-2-methylpropan-2-ylamino)-1-hydroxyethyl)pyrrolidin-1-yl)methyl)benzonitrile
Show/Hide
|
C25H30N4OS
|
1
|
| 1 |
IC50 = 1350 nM
|
|
|
|
CP0506524
|
(S)-1-(3-methoxyphenoxy)-3-(1-(4-methoxyphenyl)-2-methylpropan-2-ylamino)propan-2-ol
Show/Hide
|
C21H29NO4
|
1
|
| 1 |
IC50 = 1390 nM
|
|
|
|
CP0516017
|
2-(((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)ethyl)pyrrolidin-1-yl)methyl)-6-methoxyphenol
Show/Hide
|
C28H36N2O3
|
1
|
| 1 |
IC50 = 1560 nM
|
|
|
|
CP0449586
|
(R)-1-((R)-1-(3-bromobenzyl)pyrrolidin-2-yl)-2-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)ethanol
Show/Hide
|
C27H33BrN2O
|
1
|
| 1 |
IC50 = 1570 nM
|
|
|
|
CP0562108
|
(R)-1-((R)-1-Biphenyl-3-ylmethyl-pyrrolidin-2-yl)-2-(1,1-dimethyl-2-naphthalen-2-yl-ethylamino)-ethanol
Show/Hide
|
C33H38N2O
|
1
|
| 1 |
IC50 = 2470 nM
|
|
|
|
CP0464572
|
3-(((R)-2-((R)-1-hydroxy-2-(1-(4-methoxyphenyl)-2-methylpropan-2-ylamino)ethyl)pyrrolidin-1-yl)methyl)benzonitrile
Show/Hide
|
C25H33N3O2
|
1
|
| 1 |
IC50 = 2670 nM
|
|
|
|
CP0562086
|
3-(((R)-2-((R)-2-(1-(1H-benzo[d]imidazol-2-yl)-2-methylpropan-2-ylamino)-1-hydroxyethyl)pyrrolidin-1-yl)methyl)benzonitrile
Show/Hide
|
C25H31N5O
|
1
|
| 1 |
IC50 = 2840 nM
|
|
|
|
CP0500649
|
(R)-1-(1-(4-fluorophenyl)-2-methylpropan-2-ylamino)-3-(4-(trifluoromethoxy)phenoxy)propan-2-ol
Show/Hide
|
C20H23F4NO3
|
1
|
| 1 |
IC50 = 3300 nM
|
|
|
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CP0500651
|
(R)-2-chloro-6-(2-hydroxy-3-(2-(naphthalen-2-yl)ethylamino)propoxy)benzonitrile
Show/Hide
|
C22H21ClN2O2
|
1
|
| 1 |
IC50 = 3860 nM
|
|
|
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CP0500650
|
(R)-2-chloro-6-(2-hydroxy-3-(naphthalen-2-ylamino)propoxy)benzonitrile
Show/Hide
|
C20H17ClN2O2
|
1
|
| 1 |
IC50 = 4600 nM
|
|
|
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CP0464574
|
(R)-1-(2,3-dichlorophenylthio)-3-(1-(4-fluorophenyl)-2-methylpropan-2-ylamino)propan-2-ol
Show/Hide
|
C19H22Cl2FNOS
|
1
|
| 1 |
IC50 = 6180 nM
|
|
|
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CP0442528
|
3-(((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)ethyl)pyrrolidin-1-yl)methyl)benzoic acid
Show/Hide
|
C28H34N2O3
|
1
|
| 1 |
IC50 = 6840 nM
|
|
|
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CP0442527
|
3-((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)ethyl)pyrrolidine-1-carbonyl)benzonitrile
Show/Hide
|
C28H31N3O2
|
1
|
| 1 |
IC50 = 8430 nM
|
|
|
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CP0523116
|
(S)-1-(2-methyl-1-phenylpropan-2-ylamino)-3-(2-(methylsulfonyl)phenoxy)propan-2-ol
Show/Hide
|
C20H27NO4S
|
1
|
| 1 |
IC50 = 9430 nM
|
|
|
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CP0500648
|
1-(1-(4-methoxyphenyl)-2-methylpropan-2-ylamino)-3-(3-methyl-4-(methylsulfonyl)phenoxy)propan-2-ol
Show/Hide
|
C22H31NO5S
|
1
|
| 1 |
IC50 = 11360 nM
|
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