Brief Information of the Cell Line and Protein
Cell Line ID: CL000384 , 3T3-L1
Synonyms
3T3 L1
3T3L1
3T3-L1 ad
NIH-3T3-L1
NIH3T3-L1
Category Spontaneously immortalized cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_0123
Protein ID: PT05069 , Insulin receptor
Gene Name INSR
Organism Mus musculus, Mouse
Protein Classification Kinase
Uniprot ID P15208
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000384  Protein ID: PT05069
 
Compound ID Compound Name Compound Formula
CP0806684
2-Chloro-5-{[(7-{[(7-{[(4-chloro-3-sulfophenyl)amino]sulfonyl}-5-hydroxy(2-naphthyl))amino]carbonylamino}-4-hydroxy(2-naphthyl))sulfonyl]amino}benzenesulfonic Acid, Disodium Salt
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C33H22Cl2N4Na2O13S4
 1
1
EC50 = 5000 nM
   TI
   LI
   LO
   TS
CP0867006
2-Chloro-5-{[(7-{[(7-{[(4-chloro-3-sulfophenyl)amino]sulfonyl}(2-naphthyl))amino]carbonylamino}(2-naphthyl))sulfonyl]amino}benzenesulfonic acid, Disodium Salt
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C33H22Cl2N4Na2O11S4
 1
1
EC50 = 6000 nM
   TI
   LI
   LO
   TS
CP0418534
2-Hydroxy-5-{[(7-{[(7-sulfo(2-naphthyl))amino]carbonylamino}(2-naphthyl))sulfonyl]amino}benzoic Acid
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C35H26N4O11S2
 1
1
EC50 = 9000 nM
   TI
   LI
   LO
   TS
CP0501084
5-{[(7-{[(7-{[(3-Carboxy-4-chlorophenyl)amino]sulfonyl}(2-naphthyl))amino]carbonylamino}(2-naphthyl))sulfonyl]amino}-2-chlorobenzoicAcid
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C35H24Cl2N4O9S2
 1
1
EC50 = 16000 nM
   TI
   LI
   LO
   TS
CP0531997
5-{[(7-{[(7-{[(3-Carboxy-4-chlorophenyl)amino]sulfonyl}-5-hydroxy(2-naphthyl))amino]carbonylamino}-4-hydroxy(2-naphthyl))-sulfonyl]amino}-2-chlorobenzoic Acid
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C35H24Cl2N4O11S2
 1
1
EC50 = 18000 nM
   TI
   LI
   LO
   TS
CP0916703
3-{[(7-{[(7-{[(3-Sulfophenyl)amino]sulfonyl}-2-naphthyl)amino]carbonylamino}-2-naphthyl)sulfonyl]amino}benzenesulfonic Acid Disodium Salt
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C33H24N4Na2O11S4
 1
1
EC50 = 22000 nM
   TI
   LI
   LO
   TS
CP0526805
3-{7-[({7-[(3-carboxyphenyl)sulfamoyl]naphthalen-2-yl}carbamoyl)amino]naphthalene-2-sulfonamido}benzoic acid
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C35H26N4O9S2
 1
1
EC50 = 24000 nM
   TI
   LI
   LO
   TS
CP0762060
3-{[(4-Hydroxy-7-{[(5-hydroxy-7-{[(3-sulfophenyl)amino]sulfonyl}(2-naphthyl))amino]carbonylamino}-2-naphthyl)sulfonyl]-amino}benzenesulfonic Acid, Disodium Salt
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C33H24N4Na2O13S4
 1
1
EC50 = 26000 nM
   TI
   LI
   LO
   TS
CP0467658
5-{7-[({7-[(3-carboxy-4-nitrophenyl)sulfamoyl]naphthalen-2-yl}carbamoyl)amino]naphthalene-2-sulfonamido}-2-nitrobenzoic acid
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C35H24N6O13S2
 1
1
EC50 = 40000 nM
   TI
   LI
   LO
   TS
CP0481493
2-{7-[({7-[(2-carboxyphenyl)sulfamoyl]naphthalen-2-yl}carbamoyl)amino]naphthalene-2-sulfonamido}benzoic acid
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C35H26N4O9S2
 1
1
EC50 = 41000 nM
   TI
   LI
   LO
   TS
CP0462303
3-{7-[({7-[(3-carboxyphenyl)sulfamoyl]-5-hydroxynaphthalen-2-yl}carbamoyl)amino]-4-hydroxynaphthalene-2-sulfonamido}benzoic acid
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C35H26N4O11S2
 1
1
EC50 = 43000 nM
   TI
   LI
   LO
   TS
CP0511582
5-{[(7-{[(7-{[(3-Carboxy-4-hydroxyphenyl)amino]sulfonyl}-5-hydroxy(2-naphthyl))amino]carbonylamino}-4-hydroxy(2-naphthyl))-sulfonyl]amino}-2-hydroxybenzoic Acid
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C35H26N4O13S2
 1
1
EC50 = 43000 nM
   TI
   LI
   LO
   TS
CP0488047
1,3-bis(7-{[3-(1H-1,2,3,4-tetrazol-1-yl)phenyl]sulfamoyl}naphthalen-2-yl)urea
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C35H26N12O5S2
 1
1
EC50 = 54000 nM
   TI
   LI
   LO
   TS
CP0508103
5-[({7-[3-(7-{[(3-Carboxy-4-chlorophenyl)amino]sulfonyl}(2-naphthyl))-2-oxoimidazolidinyl](2-naphthyl)}sulfonyl)amino]-2-chlorobenzoicAcid
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C37H26Cl2N4O9S2
 1
1
EC50 = 56000 nM
   TI
   LI
   LO
   TS
CP0526804
1,3-bis(5-hydroxy-7-{[3-(1H-1,2,3,4-tetrazol-1-yl)phenyl]sulfamoyl}naphthalen-2-yl)urea
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C35H26N12O7S2
 1
1
EC50 = 73000 nM
   TI
   LI
   LO
   TS
CP0824225
TLK 16998
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C45H32N10O21S6
 1
1
EC50 = 90000 nM
   TI
   LI
   LO
   TS
CP0868250
disodium 3-{N-methyl7-[({7-[methyl(3-sulfonatophenyl)sulfamoyl]naphthalen-2-yl}carbamoyl)amino]naphthalene-2-sulfonamido}benzene-1-sulfonate
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C35H28N4Na2O11S4
 1
1
EC50 = 91000 nM
   TI
   LI
   LO
   TS
CP0528425
2-{7-[({7-[(2-carboxyphenyl)sulfamoyl]-5-hydroxynaphthalen-2-yl}carbamoyl)amino]-4-hydroxynaphthalene-2-sulfonamido}benzoic acid
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C35H26N4O11S2
 1
1
EC50 = 93000 nM
   TI
   LI
   LO
   TS
CP0926750
disodium 4-{7-[({7-[(4-sulfonatophenyl)sulfamoyl]naphthalen-2-yl}carbamoyl)amino]naphthalene-2-sulfonamido}benzene-1-sulfonate
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C33H24N4Na2O11S4
 1
1
EC50 = 94000 nM
   TI
   LI
   LO
   TS