| Compound ID |
Compound Name |
Compound Formula |
|
CP0366445
|
2-(4-(3-fluorophenyl)piperidine-1-carbonyl)-4-(2-methoxyethyl)-3-methylisoxazol-5(2H)-one
Show/Hide
|
C19H23FN2O4
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0089605
|
3-Methyl-4-(2-phenoxy-ethyl)-2-(piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C18H22N2O4
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0130731
|
4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxylic acid methyl-thiophen-2-ylmethyl-amide
Show/Hide
|
C14H18N2O3S
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0053132
|
4-(2-Methoxy-ethyl)-3-methyl-2-(4-m-tolyl-piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C20H26N2O4
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0162696
|
2-(4-(3-fluorophenyl)piperidine-1-carbonyl)-4-isopropyl-3-methylisoxazol-5(2H)-one
Show/Hide
|
C19H23FN2O3
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0347863
|
4-Isobutyl-3-methyl-2-(4-phenyl-piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C20H26N2O3
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0362689
|
4-(2-Methoxy-ethyl)-3-methyl-2-(4-phenyl-piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C19H24N2O4
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0164003
|
4-Cyclopentyl-3-methyl-2-(4-phenyl-piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C21H26N2O3
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0276954
|
4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxylic acid furan-2-ylmethyl-methyl-amide
Show/Hide
|
C14H18N2O4
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0163555
|
4-Butyl-3-methyl-2-(4-methyl-piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C15H24N2O3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0360894
|
4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxylic acid (2-fluoro-benzyl)-methyl-amide
Show/Hide
|
C16H19FN2O3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0173036
|
4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxylic acid (3-fluoro-benzyl)-methyl-amide
Show/Hide
|
C16H19FN2O3
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0361036
|
4-Isopropyl-2-[4-(3-methoxy-phenyl)-piperazine-1-carbonyl]-3-methyl-2H-isoxazol-5-one
Show/Hide
|
C19H25N3O4
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0052461
|
4-Isobutyl-3-methyl-2-(4-methyl-piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C15H24N2O3
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0103269
|
4-(2-Ethoxy-ethyl)-3-methyl-2-(4-methyl-piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C15H24N2O4
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0171544
|
4-Cyclohexyl-3-methyl-2-(4-methyl-piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C17H26N2O3
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0288317
|
4-Cyclopentyl-3-methyl-2-(piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C15H22N2O3
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0119105
|
3-Methyl-2-(4-methyl-piperidine-1-carbonyl)-4-(tetrahydro-thiopyran-4-yl)-2H-isoxazol-5-one
Show/Hide
|
C16H24N2O3S
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0279609
|
4-Isopropyl-3-methyl-2-(4-phenyl-piperazine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C18H23N3O3
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0362688
|
4-Cyclohexyl-3-methyl-2-(piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C16H24N2O3
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0095675
|
(S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-carbonyl)isoxazol-5(2H)-one
Show/Hide
|
C14H22N2O3
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0182153
|
4-Isopropyl-3-methyl-2-(pyrrolidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C12H18N2O3
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0065171
|
2-(1-(2-chlorophenyl)piperazine-4-carbonyl)-4-isopropyl-3-methylisoxazol-5(2H)-one
Show/Hide
|
C18H22ClN3O3
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0193921
|
4-Isobutyl-3-methyl-2-(piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C14H22N2O3
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0245889
|
4-Isopropyl-3-methyl-2-(4-phenyl-piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C19H24N2O3
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0216362
|
4-Isopropyl-3-methyl-2-(4-methyl-piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C14H22N2O3
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0276941
|
2-(3,3-Dimethyl-piperidine-1-carbonyl)-4-isopropyl-3-methyl-2H-isoxazol-5-one
Show/Hide
|
C15H24N2O3
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0292336
|
1-(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carbonyl)-piperidine-4-carboxylic acid ethyl ester
Show/Hide
|
C16H24N2O5
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0299703
|
4-Isopropyl-3-methyl-2-(4-pyrimidin-2-yl-piperazine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C16H21N5O3
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0367679
|
2-(1-benzylpiperazine-4-carbonyl)-4-isopropyl-3-methylisoxazol-5(2H)-one
Show/Hide
|
C19H25N3O3
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
|
CP0340097
|
4-Butyl-3-methyl-2-(piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C14H22N2O3
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0358401
|
4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxylic acid benzyl-methyl-amide
Show/Hide
|
C16H20N2O3
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0293366
|
4-Isopropyl-3-methyl-2-[4-(4-methyl-3H-isoxazol-2-yl)-piperidine-1-carbonyl]-2H-isoxazol-5-one
Show/Hide
|
C17H25N3O4
|
1
|
| 1 |
IC50 = 73 nM
|
|
|
|
CP0511592
|
4-Isopropyl-3-methyl-2-(piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C13H20N2O3
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0110236
|
4-tert-Butyl-3-methyl-2-(piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C14H22N2O3
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0358378
|
4-Benzyl-3-methyl-2-(piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C17H20N2O3
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0340099
|
3-Methyl-2-(piperidine-1-carbonyl)-4-(tetrahydro-thiopyran-4-yl)-2H-isoxazol-5-one
Show/Hide
|
C15H22N2O3S
|
1
|
| 1 |
IC50 = 98 nM
|
|
|
|
CP0089489
|
2-(2,5-Dihydro-pyrrole-1-carbonyl)-4-isopropyl-3-methyl-2H-isoxazol-5-one
Show/Hide
|
C12H16N2O3
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0081303
|
4-(4-Chloro-phenylsulfanyl)-3-methyl-2-(piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C16H17ClN2O3S
|
1
|
| 1 |
IC50 = 135 nM
|
|
|
|
CP0079352
|
2-(3,5-Dimethyl-piperidine-1-carbonyl)-4-isopropyl-3-methyl-2H-isoxazol-5-one
Show/Hide
|
C15H24N2O3
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0347455
|
1-(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carbonyl)-piperidin-4-one
Show/Hide
|
C13H18N2O4
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0502190
|
3-Methyl-4-phenyl-2-(piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C16H18N2O3
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0326474
|
1-(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carbonyl)-piperidine-3-carboxylic acid ethyl ester
Show/Hide
|
C16H24N2O5
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0221894
|
4-{[(1H-Indol-2-yl)-methyl-amino]-methyl}-3-methyl-2-(piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C20H24N4O3
|
1
|
| 1 |
IC50 = 177 nM
|
|
|
|
CP0044486
|
4-(2-Methoxy-ethyl)-3-methyl-2-(piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C13H20N2O4
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0536670
|
(R)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-carbonyl)isoxazol-5(2H)-one
Show/Hide
|
C14H22N2O3
|
1
|
| 1 |
IC50 = 187 nM
|
|
|
|
CP0222002
|
4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxylic acid methyl-phenyl-amide
Show/Hide
|
C15H18N2O3
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0289076
|
3-Methyl-4-phenylsulfanyl-2-(piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C16H18N2O3S
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0055468
|
3-Methyl-2-(piperidine-1-carbonyl)-4-(tetrahydro-pyran-4-yl)-2H-isoxazol-5-one
Show/Hide
|
C15H22N2O4
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0367680
|
2-(Azepane-1-carbonyl)-4-isopropyl-3-methyl-2H-isoxazol-5-one
Show/Hide
|
C14H22N2O3
|
1
|
| 1 |
IC50 = 215 nM
|
|
|
|
CP0184100
|
4-Isopropyl-3-methyl-2-(4-p-tolyl-piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C20H26N2O3
|
1
|
| 1 |
IC50 = 246 nM
|
|
|
|
CP0153162
|
4-Isopropyl-3-methyl-2-(thiomorpholine-4-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C12H18N2O3S
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0221895
|
4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxylic acid methyl-phenethyl-amide
Show/Hide
|
C17H22N2O3
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0348095
|
4-Ethyl-3-methyl-2-(piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C12H18N2O3
|
1
|
| 1 |
IC50 = 325 nM
|
|
|
|
CP0216352
|
4-(1,1-Dioxo-hexahydro-1lambda*6*-thiopyran-4-yl)-3-methyl-2-(piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C15H22N2O5S
|
1
|
| 1 |
IC50 = 380 nM
|
|
|
|
CP0216357
|
4-Isopropyl-3-methyl-2-(2-methyl-piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C14H22N2O3
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0361037
|
2-(4-Hydroxy-piperidine-1-carbonyl)-4-isopropyl-3-methyl-2H-isoxazol-5-one
Show/Hide
|
C13H20N2O4
|
1
|
| 1 |
IC50 = 450 nM
|
|
|
|
CP0347861
|
4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxylic acid diethylamide
Show/Hide
|
C12H20N2O3
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0038386
|
3,4-Dimethyl-2-(piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C11H16N2O3
|
1
|
| 1 |
IC50 = 655 nM
|
|
|
|
CP0360691
|
2-(3-(hydroxymethyl)piperidine-1-carbonyl)-4-isopropyl-3-methylisoxazol-5(2H)-one
Show/Hide
|
C14H22N2O4
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0222001
|
4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxylic acid (4-fluoro-benzyl)-methyl-amide
Show/Hide
|
C16H19FN2O3
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0288331
|
4-(4-Chloro-benzenesulfonyl)-3-methyl-2-(piperidine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C16H17ClN2O5S
|
1
|
| 1 |
IC50 = 1270 nM
|
|
|
|
CP0044487
|
2-(4-Hydroxy-4-phenyl-piperidine-1-carbonyl)-4-isopropyl-3-methyl-2H-isoxazol-5-one
Show/Hide
|
C19H24N2O4
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0052421
|
4-Isopropyl-3-methyl-2-(morpholine-4-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C12H18N2O4
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0097397
|
2-(3,4-Dihydro-2H-quinoline-1-carbonyl)-4-isopropyl-3-methyl-2H-isoxazol-5-one
Show/Hide
|
C17H20N2O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0160252
|
4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxylic acid methyl-(4-methyl-benzyl)-amide
Show/Hide
|
C17H22N2O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0171038
|
2-(4-Benzoyl-piperidine-1-carbonyl)-4-isopropyl-3-methyl-2H-isoxazol-5-one
Show/Hide
|
C20H24N2O4
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0173065
|
4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxylic acid benzyl-methyl-amide
Show/Hide
|
C15H24N2O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0221896
|
2-(4-Benzyl-piperidine-1-carbonyl)-4-isopropyl-3-methyl-2H-isoxazol-5-one
Show/Hide
|
C20H26N2O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0268866
|
4-Isopropyl-3-methyl-2-(4-methyl-piperazine-1-carbonyl)-2H-isoxazol-5-one
Show/Hide
|
C13H21N3O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0310964
|
2-(2,5-Dimethyl-piperidine-1-carbonyl)-4-isopropyl-3-methyl-2H-isoxazol-5-one
Show/Hide
|
C15H24N2O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0363775
|
4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxylic acid (4-chloro-phenyl)-methyl-amide
Show/Hide
|
C15H17ClN2O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
