Brief Information of the Cell Line and Protein
Cell Line ID: CL000261 , SK-BR-3
 Cell Line Info 
Synonyms
SK-Br-3
Sk-Br-3
SK BR 03
SKBR-3
SKBr-3
SK-BR3
SKBr3
SkBr3
SKBR3
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0033
Protein ID: PT01500 , Heat shock protein HSP 90-alpha
 Protein Info 
Gene Name HSP90AA1
Organism Homo sapiens, Human
Protein Classification Other cytosolic protein
Uniprot ID P07900
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000261
 Cell Line Info 
 Protein ID: PT01500
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0083379
 Compound Info 
8-(6-Bromo-benzo[1,3]dioxol-5-ylsulfanyl)-9-pent-4-ynyl-9H-purin-6-ylamine
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C17H14BrN5O2S
  1
1
EC50 = 20 nM
 Bioactivity Info 
   TI
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CP0215840
 Compound Info 
8-Sulfanyladenine
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C17H16IN5OS
  1
1
EC50 = 30 nM
 Bioactivity Info 
   TI
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CP0178978
 Compound Info 
8-(2-Chloro-3,4,5-trimethoxy-phenylsulfanyl)-2-fluoro-9-pent-4-ynyl-9H-purin-6-ylamine
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C19H19ClFN5O3S
  1
1
EC50 = 90 nM
 Bioactivity Info 
   TI
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CP0167758
 Compound Info 
8-(2-Bromo-5-methoxy-phenylsulfanyl)-9-pent-4-ynyl-9H-purin-6-ylamine
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C17H16BrN5OS
  1
1
EC50 = 130 nM
 Bioactivity Info 
   TI
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CP0167757
 Compound Info 
8-(2,5-Dimethoxy-phenylsulfanyl)-9-pent-4-ynyl-9H-purin-6-ylamine
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C18H19N5O2S
  1
1
EC50 = 160 nM
 Bioactivity Info 
   TI
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CP0444104
 Compound Info 
8-(2-chloro-3,4,5-trimethoxybenzyl)-2-fluoro-9-pent-4-ynyl-9H-purin-6-amine
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C20H21ClFN5O3
  1
1
EC50 = 170 nM
 Bioactivity Info 
   TI
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CP0367635
 Compound Info 
8-(2-Chloro-5-methoxy-phenylsulfanyl)-9-pent-4-ynyl-9H-purin-6-ylamine
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C17H16ClN5OS
  1
1
EC50 = 310 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0178953
 Compound Info 
8-(2-Chloro-3,4,5-trimethoxy-phenylsulfanyl)-9-pent-4-ynyl-9H-purin-6-ylamine
   Show/Hide
C19H20ClN5O3S
  1
1
EC50 = 330 nM
 Bioactivity Info 
   TI
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CP0041047
 Compound Info 
8-(2-Chloro-3,4,5-trimethoxy-phenylsulfanyl)-2-fluoro-9-(2-isopropoxy-ethyl)-9H-purin-6-ylamine
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C19H23ClFN5O4S
  1
1
EC50 = 470 nM
 Bioactivity Info 
   TI
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CP0392808
 Compound Info 
2-Fluoro-9-pent-4-ynyl-8-(3,4,5-trimethoxy-benzyl)-9H-purin-6-ylamine
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C20H22FN5O3
  1
1
EC50 = 1600 nM
 Bioactivity Info 
   TI
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CP0269135
 Compound Info 
2-Fluoro-9-pent-4-ynyl-8-(3,4,5-trimethoxy-phenylsulfanyl)-9H-purin-6-ylamine
   Show/Hide
C19H20FN5O3S
  1
1
EC50 = 2000 nM
 Bioactivity Info 
   TI
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CP0495377
 Compound Info 
8-(3,4,5-trimethoxybenzyl)-9-(pent-4-ynyl)-9H-purin-6-amine
   Show/Hide
C20H23N5O3
  1
1
EC50 = 3600 nM
 Bioactivity Info 
   TI
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CP0098918
 Compound Info 
9-Pent-4-ynyl-8-(3,4,5-trimethoxy-phenylsulfanyl)-9H-purin-6-ylamine
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C19H21N5O3S
  1
1
EC50 = 4200 nM
 Bioactivity Info 
   TI
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CP0098928
 Compound Info 
9-(2-Isopropoxy-ethyl)-8-(3,4,5-trimethoxy-phenylsulfanyl)-9H-purin-6-ylamine
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C19H25N5O4S
  1
1
EC50 = 5300 nM
 Bioactivity Info 
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