Brief Information of the Cell Line and Protein
Cell Line ID: CL000261 , SK-BR-3
 Cell Line Info 
Synonyms
SK-Br-3
Sk-Br-3
SK BR 03
SKBR-3
SKBr-3
SK-BR3
SKBr3
SkBr3
SKBR3
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0033
Protein ID: PT00886 , Estrogen receptor
 Protein Info 
Gene Name ESR1
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID P03372
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000261
 Cell Line Info 
 Protein ID: PT00886
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0545000
 Compound Info 
2-[4-chloro-2-(1,1-difluoroethyl)phenyl]-3-[4-[1-(3-fluoropropyl)azetidin-3-yl]oxyphenoxy]-6H-thieno[2,3-e]indazole
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C29H25ClF3N3O2S
  2
1
IC50 = 10.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 16.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0546743
 Compound Info 
N-[4-[[2-[4-chloro-2-(1,1-difluoroethyl)phenyl]-6H-thieno[2,3-e]indazol-3-yl]oxy]phenyl]-1-(3-fluoropropyl)azetidin-3-amine
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C29H26ClF3N4OS
  2
1
IC50 = 13.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 16.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0491461
 Compound Info 
6-(2,4-dichlorophenyl)-5-[4-[(3S)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7H-benzo[7]annulene-2-carboxylic acid
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C31H30Cl2FNO3
  2
1
IC50 = 17.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 57.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS