Brief Information of the Cell Line and Protein
Cell Line ID: CL000247 , MT-4
Synonyms
MT4
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_2632
Protein ID: PT01374 , T-cell surface glycoprotein CD4
Gene Name CD4
Organism Homo sapiens, Human
Protein Classification Surface antigen
Uniprot ID P01730
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000247  Protein ID: PT01374
 
Compound ID Compound Name Compound Formula
CP0226832
5-[1-(3-carboxy-5-chloro-4-hydroxyphenyl)-4-[(3S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]but-1-enyl]-3-chloro-2-hydroxybenzoic acid
   Show/Hide
C45H60Cl2O6
 1
1
EC50 = 4000 nM
   TI
   LI
   LO
   TS
CP0941779
Cosalane analogue
   Show/Hide
C65H80Cl2O12
 1
1
EC50 = 19900 nM
   TI
   LI
   LO
   TS
CP0672077
2-(4-carboxybenzyloxy)-5-{1-[3-carboxy-4-(4-carboxybenzyloxy)-5-chlorophenyl]-4-[1-(1,5-dimethylhexyl)-9a,11a-dimethylperhydrocyclopenta[a]phenanthren-7-yl]-1-butenyl}-3-chlorobenzoic acid
   Show/Hide
C61H72Cl2O10
 1
1
EC50 = 22000 nM
   TI
   LI
   LO
   TS
CP0918880
2-(3-carboxybenzyloxy)-5-{1-[3-carboxy-4-(3-carboxybenzyloxy)-5-chlorophenyl]-4-[1-(1,5-dimethylhexyl)-9a,11a-dimethylperhydrocyclopenta[a]phenanthren-7-yl]-1-butenyl}-3-chlorobenzoic acid
   Show/Hide
C61H72Cl2O10
 1
1
EC50 > 29000 nM
   TI
   LI
   LO
   TS
CP0906401
2-(2-carboxybenzyloxy)-5-{1-[3-carboxy-4-(2-carboxybenzyloxy)-5-chlorophenyl]-4-[1-(1,5-dimethylhexyl)-9a,11a-dimethylperhydrocyclopenta[a]phenanthren-7-yl]-1-butenyl}-3-chlorobenzoic acid
   Show/Hide
C61H72Cl2O10
 1
1
EC50 > 37000 nM
   TI
   LI
   LO
   TS
CP0946888
(S)-2-(5-{1-[3-((S)-1-Carboxy-2-phenyl-ethylcarbamoyl)-5-chloro-4-hydroxy-phenyl]-4-[17-(1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl]-but-1-enyl}-3-chloro-2-hydroxy-benzoylamino)-3-phenyl-propionic acid
   Show/Hide
C63H78Cl2N2O8
 1
1
EC50 > 62000 nM
   TI
   LI
   LO
   TS
CP0879427
Cosalane analogue
   Show/Hide
C65H80N2O14
 1
1
EC50 > 66000 nM
   TI
   LI
   LO
   TS
CP0895158
(S)-2-(3-Chloro-5-{1-[3-chloro-5-((S)-1,3-dicarboxy-propylcarbamoyl)-4-hydroxy-phenyl]-4-[(3S,10S,13R,17R)-17-(1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl]-but-1-enyl}-2-hydroxy-benzoylamino)-pentanedioic acid
   Show/Hide
C55H74Cl2N2O12
 1
1
EC50 = 69600 nM
   TI
   LI
   LO
   TS
CP0914949
3'',3'''-Dichloro-5'',5'''-dicarboxy-4'',4'''-di[p-carboxybenzyloxy]-4',4'-diphenyl-3beta-(1-butyl)cholestane
   Show/Hide
C61H74Cl2O10
 1
1
EC50 = 70400 nM
   TI
   LI
   LO
   TS
CP0948449
(S)-2-(3-Chloro-5-{1-[3-chloro-5-((S)-1,3-dicarboxy-propylcarbamoyl)-4-hydroxy-phenyl]-4-[(3S,10S,13R,17R)-17-(1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl]-butyl}-2-hydroxy-benzoylamino)-pentanedioic acid
   Show/Hide
C55H76Cl2N2O12
 1
1
EC50 = 73000 nM
   TI
   LI
   LO
   TS
CP0894575
2-[4-(2-carboxy-4-{1-[3-carboxy-4-(4-carboxymethylbenzyloxy)-5-chlorophenyl]-4-[1-(1,5-dimethylhexyl)-9a,11a-dimethylperhydrocyclopenta[a]phenanthren-7-yl]-1-butenyl}-6-chlorophenoxymethyl)phenyl]acetic acid
   Show/Hide
C63H76Cl2O10
 1
1
EC50 = 83800 nM
   TI
   LI
   LO
   TS
CP0900392
5-{1-{3-carboxy-4-[4-(3-carboxyphenyl)benzyloxy]-5-chlorophenyl}-4-[1-(1,5-dimethylhexyl)-9a,11a-dimethylperhydrocyclopenta[a]phenanthren-7-yl]-1-butenyl}-2-[4-(3-carboxyphenyl)benzyloxy]-3-chlorobenzoic acid
   Show/Hide
C73H80Cl2O10
 1
1
EC50 > 95000 nM
   TI
   LI
   LO
   TS
CP0947101
5-{1-{3-carboxy-4-[4-(4-carboxyphenyl)benzyloxy]-5-chlorophenyl}-4-[1-(1,5-dimethylhexyl)-9a,11a-dimethylperhydrocyclopenta[a]phenanthren-7-yl]-1-butenyl}-2-[4-(4-carboxyphenyl)benzyloxy]-3-chlorobenzoic acid
   Show/Hide
C73H80Cl2O10
 1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS