Brief Information of the Cell Line and Protein
Cell Line ID: CL000213 , EA.hy 926
 Cell Line Info 
Synonyms
EA. hy 926
EA hy 926
EA-hy926
EAhy 926
EAHY-926
EA.Hy926
EA.hy926
EAhy926
EaHy926
Eahy926
Category Hybrid cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_3901
Protein ID: PT01154 , Mineralocorticoid receptor
 Protein Info 
Gene Name NR3C2
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID P08235
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000213
 Cell Line Info 
 Protein ID: PT01154
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0233173
 Compound Info 
[(3R)-7-fluoro-4-(3-oxo-4H-1,4-benzoxazine-6-carbonyl)-2,3-dihydro-1,4-benzoxazin-3-yl]methanesulfonamide
   Show/Hide
C18H16FN3O6S
  2
1
EC50 = 0.05012 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0233170
 Compound Info 
US10017502, Example 6b
   Show/Hide
C20H18ClN3O5
  2
1
EC50 = 1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0434545
 Compound Info 
2-[(3S)-5,7-difluoro-4-(3-oxo-4H-1,4-benzoxazine-6-carbonyl)-2,3-dihydro-1,4-benzoxazin-3-yl]acetamide
   Show/Hide
C19H15F2N3O5
  2
1
EC50 = 12.59 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0536855
 Compound Info 
US10017502, Example 4b
   Show/Hide
C20H18FN3O5
  2
1
EC50 = 12.59 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0100868
 Compound Info 
methyl (1R,2S,9R,10R,11S,14R,15S,17R)-2,15-dimethyl-5,5'-dioxospiro[18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadec-6-ene-14,2'-oxolane]-9-carboxylate
   Show/Hide
C24H30O6
  2
1
EC50 = 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 63.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0244392
 Compound Info 
2-[(3S)-6-chloro-4-(3-oxo-4H-1,4-benzoxazine-6-carbonyl)-2,3-dihydro-1,4-benzoxazin-3-yl]-N-methylacetamide
   Show/Hide
C20H18ClN3O5
  2
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0368938
 Compound Info 
6-[(3S)-7-fluoro-3-methyl-2,3-dihydro-1,4-benzoxazine-4-carbonyl]-4H-1,4-benzoxazin-3-one
   Show/Hide
C18H15FN2O4
  2
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 63.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS