Brief Information of the Cell Line and Protein
Cell Line ID: CL000196 , MDA-MB-468
 Cell Line Info 
Synonyms
MDA-MB 468
MDA-MB468
MDAMB468
MDA-468
MDA468
MB468
MD Anderson-Metastatic Breast-468
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0419
Protein ID: PT01500 , Heat shock protein HSP 90-alpha
 Protein Info 
Gene Name HSP90AA1
Organism Homo sapiens, Human
Protein Classification Other cytosolic protein
Uniprot ID P07900
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000196
 Cell Line Info 
 Protein ID: PT01500
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0444104
 Compound Info 
8-(2-chloro-3,4,5-trimethoxybenzyl)-2-fluoro-9-pent-4-ynyl-9H-purin-6-amine
   Show/Hide
C20H21ClFN5O3
  1
1
EC50 = 230 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0178978
 Compound Info 
8-(2-Chloro-3,4,5-trimethoxy-phenylsulfanyl)-2-fluoro-9-pent-4-ynyl-9H-purin-6-ylamine
   Show/Hide
C19H19ClFN5O3S
  1
1
EC50 = 290 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0392808
 Compound Info 
2-Fluoro-9-pent-4-ynyl-8-(3,4,5-trimethoxy-benzyl)-9H-purin-6-ylamine
   Show/Hide
C20H22FN5O3
  1
1
EC50 = 1400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0269135
 Compound Info 
2-Fluoro-9-pent-4-ynyl-8-(3,4,5-trimethoxy-phenylsulfanyl)-9H-purin-6-ylamine
   Show/Hide
C19H20FN5O3S
  1
1
EC50 = 2200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0098918
 Compound Info 
9-Pent-4-ynyl-8-(3,4,5-trimethoxy-phenylsulfanyl)-9H-purin-6-ylamine
   Show/Hide
C19H21N5O3S
  1
1
EC50 = 2800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0495377
 Compound Info 
8-(3,4,5-trimethoxybenzyl)-9-(pent-4-ynyl)-9H-purin-6-amine
   Show/Hide
C20H23N5O3
  1
1
EC50 = 3500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0098928
 Compound Info 
9-(2-Isopropoxy-ethyl)-8-(3,4,5-trimethoxy-phenylsulfanyl)-9H-purin-6-ylamine
   Show/Hide
C19H25N5O4S
  1
1
EC50 = 4300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0372596
 Compound Info 
9-(2-Isopropoxy-ethyl)-8-(3,4,5-trimethoxy-benzyl)-9H-purin-6-ylamine
   Show/Hide
C20H27N5O4
  1
1
EC50 = 5800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS