Brief Information of the Cell Line and Protein
Cell Line ID: CL000196 , MDA-MB-468
 Cell Line Info 
Synonyms
MDA-MB 468
MDA-MB468
MDAMB468
MDA-468
MDA468
MB468
MD Anderson-Metastatic Breast-468
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0419
Protein ID: PT01478 , Heat shock protein HSP 90-beta
 Protein Info 
Gene Name HSP90AB1
Organism Homo sapiens, Human
Protein Classification Other cytosolic protein
Uniprot ID P08238
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000196
 Cell Line Info 
 Protein ID: PT01478
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0043495
 Compound Info 
8-(6-iodo-benzo[1,3]dioxol-5-ylsulfanyl)-9-(3-isopropylamino-propyl)adenine
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C18H21IN6O2S
  1
1
EC50 = 10.2 nM
 Bioactivity Info 
   TI
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CP0436149
 Compound Info 
8-(6-iodo-benzo[1,3]dioxol-5-ylsulfanyl)-9-(pent-4-ynyl)adenine
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C17H14IN5O2S
  1
1
EC50 = 10.9 nM
 Bioactivity Info 
   TI
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CP0466887
 Compound Info 
2-fluoro-8-(6-iodo-benzo[1,3]dioxol-5-ylmethyl)-9-(pent-4-ynyl)adenine
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C18H15FIN5O2
  1
1
EC50 = 23.7 nM
 Bioactivity Info 
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CP0486631
 Compound Info 
2-fluoro-8-(6-bromo-benzo[1,3]dioxol-5-ylmethyl)-9-(pent-4-ynyl)adenine
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C18H15BrFN5O2
  1
1
EC50 = 30.5 nM
 Bioactivity Info 
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CP0040552
 Compound Info 
2-FLUORO-8-[(6-IODO-1,3-BENZODIOXOL-5-YL)METHYL]-9-[3-(ISOPROPYLAMINO)PROPYL]-9H-PURIN-6-AMINE
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C19H22FIN6O2
  1
1
EC50 = 39.1 nM
 Bioactivity Info 
   TI
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CP0436222
 Compound Info 
2-fluoro-8-(6-chloro-benzo[1,3]dioxol-5-ylmethyl)-9-(pent-4-ynyl)adenine
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C18H15ClFN5O2
  1
1
EC50 = 51.2 nM
 Bioactivity Info 
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CP0486632
 Compound Info 
8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE
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C18H21BrN6O2S
  1
1
EC50 = 55.4 nM
 Bioactivity Info 
   TI
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CP0083379
 Compound Info 
8-(6-Bromo-benzo[1,3]dioxol-5-ylsulfanyl)-9-pent-4-ynyl-9H-purin-6-ylamine
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C17H14BrN5O2S
  1
1
EC50 = 77.1 nM
 Bioactivity Info 
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CP0407884
 Compound Info 
2-fluoro-8-(2-chloro-4,5-dimethoxy-benzyl)-9-(pent-4-ynyl)-adenine
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C19H19ClFN5O2
  1
1
EC50 = 4500 nM
 Bioactivity Info 
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CP0407885
 Compound Info 
2-fluoro-8-(2-bromo-4,5-dimethoxy-benzyl)-9-(pent-4-ynyl)-adenine
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C19H19BrFN5O2
  1
1
EC50 > 15000 nM
 Bioactivity Info 
   TI
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CP0466888
 Compound Info 
2-fluoro-8-(2-iodo-4,5-dimethoxy-benzyl)-9-(pent-4-ynyl)-adenine
   Show/Hide
C19H19FIN5O2
  1
1
EC50 > 15000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS