Brief Information of the Cell Line and Protein
Cell Line ID: CL000159 , L-02
Synonyms
L02
LO2
HL-7702
HL7702
Liver-02
Human Liver-7702
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_6926
Protein ID: PT01555 , Oxysterols receptor LXR-alpha
Gene Name NR1H3
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID Q13133
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000159  Protein ID: PT01555
 
Compound ID Compound Name Compound Formula
CP0003740
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide
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C17H12F9NO3S
 1
1
EC50 = 530 nM
   TI
   LI
   LO
   TS
CP0492197
(1R,4R)-1-benzyl-1,10-dihydroxy-4-methyl-2,4-dihydropyrazino[2,1-b]quinazoline-3,6-dione
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C19H17N3O4
 1
1
EC50 = 1700 nM
   TI
   LI
   LO
   TS
CP0567671
(1Z,4R)-1-benzylidene-10-hydroxy-4-methyl-4H-pyrazino[2,1-b]quinazoline-3,6-dione
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C19H15N3O3
 1
1
EC50 = 1700 nM
   TI
   LI
   LO
   TS
CP0417054
(1S,4R)-1-benzyl-10-hydroxy-1-methoxy-4-methyl-2,4-dihydropyrazino[2,1-b]quinazoline-3,6-dione
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C20H19N3O4
 1
1
EC50 = 5100 nM
   TI
   LI
   LO
   TS
CP0417055
(1S,4R)-1-benzyl-1,10-dihydroxy-4-methyl-2,4-dihydropyrazino[2,1-b]quinazoline-3,6-dione
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C19H17N3O4
 1
1
EC50 = 5300 nM
   TI
   LI
   LO
   TS
CP0417056
(4R,7R)-4-benzyl-4-methoxy-7-methyl-15-oxa-2,5,8-triazatricyclo[8.5.0.03,8]pentadeca-1(10),2,11,13-tetraene-6,9-dione
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C20H19N3O4
 1
1
EC50 = 15000 nM
   TI
   LI
   LO
   TS
CP0541814
(4S,7R)-4-benzyl-4-methoxy-7-methyl-15-oxa-2,5,8-triazatricyclo[8.5.0.03,8]pentadeca-1(10),2,11,13-tetraene-6,9-dione
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C20H19N3O4
 1
1
EC50 = 15000 nM
   TI
   LI
   LO
   TS
CP0548205
(4R,7R)-4-benzyl-4-hydroxy-7-methyl-15-oxa-2,5,8-triazatricyclo[8.5.0.03,8]pentadeca-1(10),2,11,13-tetraene-6,9-dione
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C19H17N3O4
 1
1
EC50 = 16000 nM
   TI
   LI
   LO
   TS
CP0562940
(7S,10R)-7-benzyl-4-[(2R)-butan-2-yl]-10-methoxy-15-oxa-2,5,8-triazatricyclo[8.5.0.03,8]pentadeca-1,3,11,13-tetraene-6,9-dione
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C23H25N3O4
 1
1
EC50 = 41000 nM
   TI
   LI
   LO
   TS
CP0552780
(4S,7R)-4-benzyl-4-hydroxy-7-methyl-15-oxa-2,5,8-triazatricyclo[8.5.0.03,8]pentadeca-1(10),2,11,13-tetraene-6,9-dione
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C19H17N3O4
 1
1
EC50 = 47000 nM
   TI
   LI
   LO
   TS
CP0492198
(4Z,7R)-4-benzylidene-7-methyl-15-oxa-2,5,8-triazatricyclo[8.5.0.03,8]pentadeca-1(10),2,11,13-tetraene-6,9-dione
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C19H15N3O3
 1
1
EC50 = 50000 nM
   TI
   LI
   LO
   TS