Brief Information of the Cell Line and Protein
Cell Line ID: CL000149 , HOS
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0312
Protein ID: PT02059 , C-X-C chemokine receptor type 4
Gene Name CXCR4
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P61073
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000149  Protein ID: PT02059
 
Compound ID Compound Name Compound Formula
CP0444193
(6,6-dimethyl-5H-imidazo[2,1-b][1,3]thiazol-3-yl)methyl N'-[4-[[[2-[2-[6-[[2-[2-[[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]amino]-2-oxoethoxy]acetyl]amino]hexylamino]-2-oxoethoxy]acetyl]amino]methyl]cyclohexyl]-N-cyclohexylcarbamimidothioate
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C56H83N9O9S2
 1
1
IC50 = 3300 nM
   TI
   LI
   LO
   TS
CP0069850
(6,6-dimethyl-5,6-dihydroimidazo[2,1-b][1,3]thiazol-3-yl)methyl N,N'-dicyclohexylimidothiocarbamate
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C21H34N4S2
 1
1
IC50 = 32600 nM
   TI
   LI
   LO
   TS
CP0444195
(6,6-dimethyl-5H-imidazo[2,1-b][1,3]thiazol-3-yl)methyl N-cyclohexyl-N'-[4-[[[2-[2-[6-[[2-[2-(methylamino)-2-oxoethoxy]acetyl]amino]hexylamino]-2-oxoethoxy]acetyl]amino]methyl]cyclohexyl]carbamimidothioate
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C37H62N8O6S2
 1
1
IC50 = 78300 nM
   TI
   LI
   LO
   TS