Brief Information of the Cell Line and Protein
Cell Line ID: CL000131 , HEK293-F
Synonyms
HEK-293-F
HEK 293-F
HEK-293F
HEK293F
293-F
293 F
293F
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_6642
Protein ID: PT02025 , Prostaglandin E synthase
Gene Name PTGES
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID O14684
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000131  Protein ID: PT02025
 
Compound ID Compound Name Compound Formula
CP0389263
[(1S,7R,9S,12R,15S)-1,7-dicyano-12,15-dimethyl-16-[(2S)-6-methylheptan-2-yl]-3,5-dioxo-4-phenyl-2,4,6-triazapentacyclo[11.7.0.02,6.07,12.015,19]icosan-9-yl] acetate
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C37H49N5O4
 1
1
IC50 = 276 nM
   TI
   LI
   LO
   TS
CP0446660
5-[(E)-C-[(E)-2-(1,3-benzodioxol-5-yl)ethenyl]-N-(2,4-dinitroanilino)carbonimidoyl]-N-(3,4-dichlorophenyl)-1,3-thiazol-2-amine
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C25H16Cl2N6O6S
 1
1
IC50 = 284 nM
   TI
   LI
   LO
   TS
CP0489071
CIBA-1906
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C19H25N3OS
 1
1
IC50 = 370 nM
   TI
   LI
   LO
   TS
CP0559039
3-[5-[4-[4-[2-(3-cyanophenyl)-1,3-dioxo-4,6,7-triphenylisoindol-5-yl]phenyl]sulfanylphenyl]-1,3-dioxo-4,6,7-triphenylinden-2-yl]benzonitrile
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C79H47N3O4S
 1
1
IC50 = 439 nM
   TI
   LI
   LO
   TS
CP0446659
N-[(Z)-[3-(6-benzoyl-3-oxo-4H-quinoxalin-2-yl)-1-(2-methylanilino)-1-oxopropan-2-ylidene]amino]pyridine-4-carboxamide
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C31H24N6O4
 1
1
IC50 = 664 nM
   TI
   LI
   LO
   TS
CP0390089
1-[2-(N-(4-bromoanilino)-2-methoxyanilino)phenyl]-2-(4-bromophenyl)-1-(4-methoxyphenyl)hydrazine
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C32H28Br2N4O2
 1
1
IC50 = 889 nM
   TI
   LI
   LO
   TS
CP0555681
3-[[2-tert-butyl-5-chloro-4-[[6-(4-chlorophenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl]methoxy]phenoxy]methyl]-6-(4-chlorophenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
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C30H23Cl3N8O2S2
 1
1
IC50 = 917 nM
   TI
   LI
   LO
   TS