Brief Information of the Cell Line and Protein
Cell Line ID: CL000131 , HEK293-F
Synonyms
HEK-293-F
HEK 293-F
HEK-293F
HEK293F
293-F
293 F
293F
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_6642
Protein ID: PT00975 , Dipeptidyl peptidase 8
Gene Name DPP8
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID Q6V1X1
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000131  Protein ID: PT00975
 
Compound ID Compound Name Compound Formula
CP0844246
5-(Aminomethyl)-6-(2,2-dimethylpropyl)-4-(4-methylphenyl)-2-(2-methylpropyl)pyridine-3-carboxylic Acid Dihydrochloride
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C23H34Cl2N2O2
 1
1
IC50 = 420 nM
   TI
   LI
   LO
   TS
CP0803636
5-(Aminomethyl)-6-(2,2-dimethylpropyl)-4-(4-methylphenyl)-2-propylpyridine-3-carboxylic Acid Dihydrochloride
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C22H32Cl2N2O2
 1
1
IC50 = 630 nM
   TI
   LI
   LO
   TS
CP0767770
5-(Aminomethyl)-6-(2,2-dimethylpropyl)-2-ethyl-4-(4-methylphenyl)pyridine-3-carboxylic Acid Dihydrochloride
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C21H30Cl2N2O2
 1
1
IC50 = 820 nM
   TI
   LI
   LO
   TS
CP0756597
5-(Aminomethyl)-2-benzyl-6-(2,2-dimethylpropyl)-4-(4-methylphenyl)pyridine-3-carboxylic Acid Dihydrochloride
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C26H32Cl2N2O2
 1
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS
CP0785521
5-(Aminomethyl)-6-(2,2-dimethylpropyl)-2-(1-methylethyl)-4-(4-methylphenyl)pyridine-3-carboxylic acid Dihydrochloride
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C22H32Cl2N2O2
 1
1
IC50 = 2300 nM
   TI
   LI
   LO
   TS
CP0772190
5-(Aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridine-3-carboxylic Acid Dihydrochloride
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C19H26Cl2N2O2
 1
1
IC50 = 11000 nM
   TI
   LI
   LO
   TS
CP0721302
5-(Aminomethyl)-6-(2,2-dimethylpropyl)-2-methyl-4-(4-methylphenyl)pyridine-3-carboxylic Acid Dihydrochloride
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C20H28Cl2N2O2
 1
1
IC50 = 12000 nM
   TI
   LI
   LO
   TS
CP0684514
1-{[5-(Aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]acetyl}-L-prolinamide dihydrochloride
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C25H36Cl2N4O2
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0767769
3-[5-(Aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]propanoic Acid Dihydrochloride
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C21H30Cl2N2O2
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0844245
[5-(Aminomethyl)-2-methyl-4-(4-methylphenyl)-6-(2-methylpropyl)pyridin-3-yl]acetic Acid Dihydrochloride
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C20H28Cl2N2O2
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0666319
1-(3-(aminomethyl)-2-isobutyl-4-p-tolylquinolin-6-yl)piperazine-2,5-dione dihydrochloride
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C25H30Cl2N4O2
 1
1
IC50 > 60000 nM
   TI
   LI
   LO
   TS
CP0752501
[5-(Aminomethyl)-6-(2,2-dimethylpropyl)-2-methyl-4-(4-methylphenyl)pyridin-3-yl]acetic Acid Dihydrochloride
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C21H30Cl2N2O2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0911852
[5-(Aminomethyl)-6-(2,2-dimethylpropyl)-2-ethyl-4-(4-methylphenyl)pyridin-3-yl]acetic acid hydrate
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C22H32N2O3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS