| Compound ID |
Compound Name |
Compound Formula |
|
CP0463188
|
6-(4-fluorophenoxy)-3-[(1-isopropylpiperidin-3-yl)methyl]-2-(2-methylphenyl)quinazolin-4(3H)-one
Show/Hide
|
C30H32FN3O2
|
1
|
| 1 |
Ki = 0.47 nM
|
|
|
|
CP0465574
|
6-(4-fluorophenoxy)-2-(2-methylphenyl)-3-(piperidin-3-ylmethyl)quinazolin-4(3H)-one
Show/Hide
|
C27H26FN3O2
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0360725
|
6-(4-chlorophenyl)-3-{[(3S)-1-ethylpiperidin-3-yl]methyl}-2-(2-methylphenyl)quinazolin-4(3H)-one
Show/Hide
|
C29H30ClN3O
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0463194
|
6-(4-chlorophenyl)-3-[(-1-ethylpiperidin-3-yl)methyl]-2-(2-methylphenyl)quinazolin-4(3H)-one
Show/Hide
|
C29H30ClN3O
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0490492
|
6-(4-chlorophenyl)-3-[(1-isopropylpiperidin-3-yl)methyl]-2-(2-methylphenyl)quinazolin-4(3H)-one
Show/Hide
|
C30H32ClN3O
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0467251
|
6-(4-chlorophenyl)-3-[(1-cyclobutylpiperidin-3-yl)methyl]-2-(2-methylphenyl)quinazolin-4(3H)-one
Show/Hide
|
C31H32ClN3O
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0277613
|
6-(4-fluorophenoxy)-2-isopropyl-3-[(1-isopropylpiperidin-3-yl)methyl]quinazolin-4(3H)-one
Show/Hide
|
C26H32FN3O2
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0464586
|
6-(4-chlorophenyl)-3-{[1-(2-methoxyethyl)piperidin-3-yl]-methyl}-2-(2-methylphenyl)quinazolin-4(3H)-one
Show/Hide
|
C30H32ClN3O2
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0463187
|
6-(4-chlorophenyl)-2-(2-methylphenyl)-3-(piperidin-3-ylmethyl)-quinazolin-4(3H)-one
Show/Hide
|
C27H26ClN3O
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0451691
|
6-(4-chlorophenyl)-3-{[1-(2-fluoroethyl)piperidin-3-yl]methyl}-2-(2-methylphenyl)quinazolin-4(3H)-one
Show/Hide
|
C29H29ClFN3O
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0474455
|
(S)-3-((1-ethylpiperidin-3-yl)methyl)-2-o-tolyl-6-(trifluoromethoxy)quinazolin-4(3H)-one
Show/Hide
|
C24H26F3N3O2
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0551270
|
(S)-6-(4-chlorophenyl)-3-((1-ethylpiperidin-3-yl)methyl)-2-(4-(trifluoromethyl)phenyl)quinazolin-4(3H)-one
Show/Hide
|
C29H27ClF3N3O
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0070682
|
6-(4-fluorophenoxy)-3-{[(3S)-1-isopropylpiperidin-3-yl]methyl}-2-methylquinazolin-4(3H)-one
Show/Hide
|
C24H28FN3O2
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0213035
|
6-(4-luorophenoxy)-3-{[(3S)-1-isopropylpiperidin-3-yl]-methyl}quinazolin-4(3H)-one
Show/Hide
|
C23H26FN3O2
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0440151
|
6-[butyl(methyl)amino]-3-[(1-ethylpiperidin-3-yl)methyl]-2-(2-methoxyphenyl)quinazolin-4-one
Show/Hide
|
C28H38N4O2
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0457973
|
3-[(1-ethylpiperidin-3-yl)methyl]-2-(2-methylphenyl)-6-(trifluoromethoxy)quinazolin-4(3H)-one
Show/Hide
|
C24H26F3N3O2
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0372508
|
6-(4-chlorophenyl)-3-[(1-ethyl-1,2,5,6-tetrahydropyridin-3-yl)-methyl]-2-(2-methylphenyl)quinazolin-4(3H)-one
Show/Hide
|
C29H28ClN3O
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0499451
|
6-[butyl(methyl)amino]-2-(2-methoxyphenyl)-3-(piperidin-3-ylmethyl)quinazolin-4-one
Show/Hide
|
C26H34N4O2
|
1
|
| 1 |
Ki = 36 nM
|
|
|
|
CP0167003
|
6-(4-fluorophenyl)-2-isopropyl-3-[(1-isopropylpiperidin-3-yl)-methyl]quinazolin-4(3H)-one
Show/Hide
|
C26H32FN3O
|
1
|
| 1 |
Ki = 39 nM
|
|
|
|
CP0474454
|
(S)-3-((1-ethylpiperidin-3-yl)methyl)-6-(4-fluorophenyl)-2-isopropylquinazolin-4(3H)-one
Show/Hide
|
C25H30FN3O
|
1
|
| 1 |
Ki = 40 nM
|
|
|
|
CP0213034
|
6-(4-chlorophenyl)-2-isopropyl-3-{[(3S)-1-isopropylpiperidin-3-yl]methyl}quinazolin-4(3H)-one
Show/Hide
|
C26H32ClN3O
|
1
|
| 1 |
Ki = 45 nM
|
|
|
|
CP0533068
|
(R)-6-(4-fluorophenoxy)-3-((1-isopropylpiperidin-3-yl)methyl)-2-o-tolylquinazolin-4(3H)-one
Show/Hide
|
C30H32FN3O2
|
1
|
| 1 |
Ki = 47 nM
|
|
|
|
CP0439761
|
6-(4-chlorophenyl)-3-{[(3R)-1-ethylpiperidin-3-yl]methyl}-2-(2-methylphenyl)quinazolin-4(3H)-one
Show/Hide
|
C29H30ClN3O
|
1
|
| 1 |
Ki = 71 nM
|
|
|
|
CP0485200
|
(R)-3-((1-ethylpiperidin-3-yl)methyl)-2-o-tolyl-6-(trifluoromethoxy)quinazolin-4(3H)-one
Show/Hide
|
C24H26F3N3O2
|
1
|
| 1 |
Ki = 95 nM
|
|
|
|
CP0213038
|
6-(4-chlorophenyl)-3-{[(3S)-1-isopropylpiperidin-3-yl]methyl}-2-methylquinazolin-4(3H)-one
Show/Hide
|
C24H28ClN3O
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0439484
|
6-(2-chlorophenyl)-2-isopropyl-3-(((S)-1-isopropylpiperidin-3-yl)methyl)quinazolin-4(3H)-one
Show/Hide
|
C26H32ClN3O
|
1
|
| 1 |
Ki = 127 nM
|
|
|
|
CP0501056
|
6-(4-chlorophenyl)-3-[(4-isopropylmorpholin-2-yl)methyl]-2-(2-methylphenyl)quinazolin-4(3H)-one
Show/Hide
|
C29H30ClN3O2
|
1
|
| 1 |
Ki = 190 nM
|
|
|
|
CP0439485
|
(R)-6-(4-chlorophenyl)-3-((1-ethylpiperidin-3-yl)methyl)-2-(4-(trifluoromethyl)phenyl)quinazolin-4(3H)-one
Show/Hide
|
C29H27ClF3N3O
|
1
|
| 1 |
Ki = 240 nM
|
|
|
|
CP0439759
|
6-(4-chlorophenyl)-2-(2-methylphenyl)-3-{[1-(3,3,3-trifluoropropyl)piperidin-3-yl]methyl}quinazolin-4(3H)-one
Show/Hide
|
C30H29ClF3N3O
|
1
|
| 1 |
Ki = 250 nM
|
|
|
|
CP0213037
|
6-(4-chlorophenyl)-3-[(1-isopropylpiperidin-3-yl)methyl]-quinazolin-4(3H)-one
Show/Hide
|
C23H26ClN3O
|
1
|
| 1 |
Ki = 440 nM
|
|
|
|
CP0463185
|
3-[(1-ethylpiperidin-3-yl)methyl]-6-methoxy-2-(2-methoxyphenyl)quinazolin-4(3H)-one
Show/Hide
|
C24H29N3O3
|
1
|
| 1 |
Ki = 910 nM
|
|
|
|
CP0497125
|
3-[(1-isopropylpiperidin-3-yl)methyl]-2-(2-methylphenyl)-quinazolin-4(3H)-one
Show/Hide
|
C24H29N3O
|
1
|
| 1 |
Ki = 1200 nM
|
|
|
|
CP0394636
|
6-(2-chlorophenyl)-2-isopropyl-3-(((R)-1-isopropylpiperidin-3-yl)methyl)quinazolin-4(3H)-one
Show/Hide
|
C26H32ClN3O
|
1
|
| 1 |
Ki = 1800 nM
|
|
|
|
CP0372507
|
6-(4-chlorophenyl)-2-(2-methylphenyl)-3-{[1-(2,2,2-trifluoroethyl)piperidin-3-yl]methyl}quinazolin-4(3H)-one
Show/Hide
|
C29H27ClF3N3O
|
1
|
| 1 |
Ki = 2000 nM
|
|
|
|
CP0485326
|
(R)-3-((1-ethylpiperidin-3-yl)methyl)-6-(4-fluorophenyl)-2-isopropylquinazolin-4(3H)-one
Show/Hide
|
C25H30FN3O
|
1
|
| 1 |
Ki = 5700 nM
|
|
|
|
CP0372446
|
7-(4-chlorophenyl)-3-[(1-ethylpiperidin-3-yl)methyl]-2-(2-methoxyphenyl)quinazolin-4(3H)-one
Show/Hide
|
C29H30ClN3O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0439762
|
6-(4-chlorophenyl)-3-[2-(1-ethylpiperidin-3-yl)ethyl]-2-(2-methoxyphenyl)quinazolin-4(3H)-one trifluoroacetate
Show/Hide
|
C30H32ClN3O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
