| Compound ID |
Compound Name |
Compound Formula |
|
CP0429024
|
N-(cyclobutylmethyl)-6-methoxy-3-[[4-(triazol-1-ylmethyl)naphthalene-1-carbonyl]amino]pyridine-2-carboxamide
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|
C26H26N6O3
|
2
|
| 1 |
EC50 = 1.3 nM
|
|
|
| 2 |
IC50 = 0.97 nM
|
|
|
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CP0429019
|
N-(cyclobutylmethyl)-3-[[4-(triazol-1-ylmethyl)naphthalene-1-carbonyl]amino]pyridine-2-carboxamide
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|
C25H24N6O2
|
2
|
| 1 |
EC50 = 1.4 nM
|
|
|
| 2 |
IC50 = 710 nM
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|
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CP0500770
|
N-(cyclohexylmethyl)-6-methoxy-3-[[4-(triazol-1-ylmethyl)naphthalene-1-carbonyl]amino]pyridine-2-carboxamide
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|
C28H30N6O3
|
2
|
| 1 |
EC50 = 1.7 nM
|
|
|
| 2 |
IC50 = 0.85 nM
|
|
|
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CP0450546
|
6-methoxy-N-(oxan-4-ylmethyl)-3-[[4-(triazol-1-ylmethyl)naphthalene-1-carbonyl]amino]pyridine-2-carboxamide
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|
C27H28N6O4
|
2
|
| 1 |
EC50 = 2.9 nM
|
|
|
| 2 |
IC50 = 2.4 nM
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|
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CP0417977
|
N-(cyclobutylmethyl)-6-[2-(2-hydroxyethoxy)ethoxy]-3-[[4-(methylsulfinylmethyl)naphthalene-1-carbonyl]amino]pyridine-2-carboxamide
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|
C28H33N3O6S
|
2
|
| 1 |
EC50 = 5.1 nM
|
|
|
| 2 |
IC50 = 7.2 nM
|
|
|
|
CP0443284
|
N-(cyclobutylmethyl)-3-[[4-(methoxymethyl)naphthalene-1-carbonyl]amino]pyridine-2-carboxamide
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|
C24H25N3O3
|
2
|
| 1 |
EC50 = 5.9 nM
|
|
|
| 2 |
IC50 = 2000 nM
|
|
|
|
CP0471357
|
N-(cyclobutylmethyl)-3-[[4-(methylsulfinylmethyl)naphthalene-1-carbonyl]amino]pyridine-2-carboxamide
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|
C24H25N3O3S
|
2
|
| 1 |
EC50 = 5.9 nM
|
|
|
| 2 |
IC50 = 7000 nM
|
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|
|
CP0417978
|
N-(oxan-4-ylmethyl)-3-[[4-(triazol-1-ylmethyl)naphthalene-1-carbonyl]amino]pyridine-2-carboxamide
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|
C26H26N6O3
|
2
|
| 1 |
EC50 = 8 nM
|
|
|
| 2 |
IC50 = 5 nM
|
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|
|
CP0450473
|
N-(cyclobutylmethyl)-3-[[4-(triazol-1-ylmethyl)naphthalene-1-carbonyl]amino]pyrazine-2-carboxamide
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|
C24H23N7O2
|
2
|
| 1 |
EC50 = 8.1 nM
|
|
|
| 2 |
IC50 = 4.3 nM
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|
|
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CP0443283
|
[6-(oxan-4-ylmethylcarbamoyl)-5-[[4-(triazol-1-ylmethyl)naphthalene-1-carbonyl]amino]pyridin-2-yl] 3,3,3-trifluoropropane-1-sulfonate
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|
C29H29F3N6O6S
|
2
|
| 1 |
EC50 = 11 nM
|
|
|
| 2 |
IC50 = 14 nM
|
|
|
|
CP0450472
|
6-methoxy-3-[[4-(methylsulfinylmethyl)naphthalene-1-carbonyl]amino]-N-(oxan-4-ylmethyl)pyridine-2-carboxamide
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|
C26H29N3O5S
|
2
|
| 1 |
EC50 = 13 nM
|
|
|
| 2 |
IC50 = 15 nM
|
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|
|
CP0482299
|
N-[2-(cyclobutylmethylcarbamoyl)-6-[2-(2-hydroxyethoxy)ethoxy]pyridin-3-yl]quinoline-4-carboxamide
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|
C25H28N4O5
|
2
|
| 1 |
EC50 = 14 nM
|
|
|
| 2 |
IC50 = 10000 nM
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|
|
CP0490347
|
N-[2-(cyclobutylmethylcarbamoyl)-6-methoxypyridin-3-yl]quinoline-4-carboxamide
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|
C22H22N4O3
|
2
|
| 1 |
EC50 = 16 nM
|
|
|
| 2 |
IC50 = 15000 nM
|
|
|
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CP0433932
|
N-(cyclobutylmethyl)-3-(naphthalene-1-carbonylamino)pyridine-2-carboxamide
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|
C22H21N3O2
|
2
|
| 1 |
EC50 = 23 nM
|
|
|
| 2 |
IC50 = 6.1 nM
|
|
|
|
CP0445501
|
N-(cyclobutylmethyl)-3-[[4-(pyrazol-1-ylmethyl)naphthalene-1-carbonyl]amino]pyridine-2-carboxamide
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|
C26H25N5O2
|
2
|
| 1 |
EC50 = 23 nM
|
|
|
| 2 |
IC50 = 13000 nM
|
|
|
|
CP0490334
|
N-(cyclohexylmethyl)-3-(naphthalene-1-carbonylamino)pyridine-2-carboxamide
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|
C24H25N3O2
|
2
|
| 1 |
EC50 = 24 nM
|
|
|
| 2 |
IC50 = 10 nM
|
|
|
|
CP0433930
|
3-[[4-[[(R)-methylsulfinyl]methyl]naphthalene-1-carbonyl]amino]-N-(oxan-4-ylmethyl)pyridine-2-carboxamide
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|
C25H27N3O4S
|
2
|
| 1 |
EC50 = 31 nM
|
|
|
| 2 |
IC50 = 21 nM
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|
|
CP0433931
|
N-(cyclobutylmethyl)-3-[[4-(imidazol-1-ylmethyl)naphthalene-1-carbonyl]amino]pyridine-2-carboxamide
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|
C26H25N5O2
|
2
|
| 1 |
EC50 = 40 nM
|
|
|
| 2 |
IC50 = 16000 nM
|
|
|
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CP0433928
|
N-[2-(cyclobutylmethylcarbamoyl)pyridin-3-yl]quinoline-4-carboxamide
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|
C21H20N4O2
|
2
|
| 1 |
EC50 = 79 nM
|
|
|
| 2 |
IC50 = 28 nM
|
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|
|
CP0433922
|
3-(naphthalene-1-carbonylamino)-N-(oxan-4-ylmethyl)pyridine-2-carboxamide
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|
C23H23N3O3
|
2
|
| 1 |
EC50 = 81 nM
|
|
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| 2 |
IC50 = 31 nM
|
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|
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CP0429018
|
3-[[4-(methylsulfinylmethyl)naphthalene-1-carbonyl]amino]-N-(oxan-4-ylmethyl)pyridine-2-carboxamide
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|
C25H27N3O4S
|
2
|
| 1 |
EC50 = 87 nM
|
|
|
| 2 |
IC50 = 49 nM
|
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|
|
CP0050487
|
(11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphthalen-1-ylcarbonyl)-9-oxa-1-azatricyclo[6.3.1.0^{4,12}]dodeca-2,4(12),5,7-tetraene
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|
C27H26N2O3
|
2
|
| 1 |
EC50 = 110 nM
|
|
|
| 2 |
IC50 = 59 nM
|
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|
|
CP0433927
|
N-[2-(cyclobutylmethylcarbamoyl)-6-(2-hydroxyethoxy)pyridin-3-yl]quinoline-4-carboxamide
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|
C23H24N4O4
|
2
|
| 1 |
EC50 = 120 nM
|
|
|
| 2 |
IC50 = 73000 nM
|
|
|
|
CP0429022
|
N-(cyclobutylmethyl)-3-[[4-(pyrrol-1-ylmethyl)naphthalene-1-carbonyl]amino]pyridine-2-carboxamide
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|
C27H26N4O2
|
2
|
| 1 |
EC50 = 170 nM
|
|
|
| 2 |
IC50 = 89000 nM
|
|
|
|
CP0477198
|
N-(cyclobutylmethyl)-3-[[4-[(dimethylamino)methyl]naphthalene-1-carbonyl]amino]pyridine-2-carboxamide
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|
C25H28N4O2
|
2
|
| 1 |
EC50 = 180 nM
|
|
|
| 2 |
IC50 = 41000 nM
|
|
|
|
CP0429023
|
N-[4-chloro-2-(cyclohexylmethylcarbamoyl)phenyl]naphthalene-1-carboxamide
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|
C25H25ClN2O2
|
2
|
| 1 |
EC50 = 260 nM
|
|
|
| 2 |
IC50 = 160 nM
|
|
|
|
CP0515467
|
N-(cyclobutylmethyl)-3-[[4-(methylsulfonylmethyl)naphthalene-1-carbonyl]amino]pyridine-2-carboxamide
Show/Hide
|
C24H25N3O4S
|
1
|
| 1 |
EC50 = 260 nM
|
|
|
|
CP0433924
|
N-(cyclohexylmethyl)-3-(naphthalene-1-carbonylamino)pyrazine-2-carboxamide
Show/Hide
|
C23H24N4O2
|
2
|
| 1 |
EC50 = 480 nM
|
|
|
| 2 |
IC50 = 91 nM
|
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|
|
CP0385225
|
N-[2-(cyclobutylmethylcarbamoyl)pyridin-3-yl]isoquinoline-5-carboxamide
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|
C21H20N4O2
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0385223
|
N-[2-(cyclobutylmethylcarbamoyl)pyridin-3-yl]quinoline-8-carboxamide
Show/Hide
|
C21H20N4O2
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0867982
|
3-[(4-{[(S)-Methylsulfinyl]methyl}-1-naphthoyl)amino]-N-(tetrahydro-2H-pyran-4-yl-methyl)pyridine-2-carboxamide
Show/Hide
|
C25H27N3O4S
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0450520
|
3-(2,3-dihydro-1,4-benzodioxine-5-carbonylamino)-N-(oxan-4-ylmethyl)pyridine-2-carboxamide
Show/Hide
|
C21H23N3O5
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0425342
|
N-(cyclohexylmethyl)-4-(naphthalene-1-carbonylamino)pyridine-3-carboxamide
Show/Hide
|
C24H25N3O2
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
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CP0482302
|
N-(cyclohexylmethyl)-3-(naphthalene-1-carbonylamino)pyridine-4-carboxamide
Show/Hide
|
C24H25N3O2
|
1
|
| 1 |
IC50 = 3600 nM
|
|
|
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CP0433923
|
N-(cyclohexylmethyl)-2-(naphthalene-1-carbonylamino)pyridine-3-carboxamide
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|
C24H25N3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0385226
|
N-[2-(oxan-4-ylmethylcarbamoyl)pyridin-3-yl]-1,3-benzothiazole-6-carboxamide
Show/Hide
|
C20H20N4O3S
|
1
|
| 1 |
IC50 > 6700 nM
|
|
|
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CP0490348
|
N-[2-(oxan-4-ylmethylcarbamoyl)pyridin-3-yl]quinoxaline-5-carboxamide
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|
C21H21N5O3
|
1
|
| 1 |
IC50 > 9900 nM
|
|
|
