Brief Information of the Cell Line and Protein
Cell Line ID: CL000094 , 1321N1
Synonyms
1321-N1
1321 N1
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0110
Protein ID: PT02444 , Metabotropic glutamate receptor 1
Gene Name GRM1
Organism Rattus norvegicus, Rat
Protein Classification Membrane receptor
Uniprot ID P23385
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000094  Protein ID: PT02444
 
Compound ID Compound Name Compound Formula
CP0205005
3-azepan-1-yl-9-dimethylamino-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one
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C17H21N5OS
 1
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
CP0170781
9-Dimethylamino-3-(4-ethyl-phenyl)-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one
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C19H18N4OS
 1
1
IC50 = 5 nM
   TI
   LI
   LO
   TS
CP0446341
9-dimethylamino-3-(3-fluoro-4-methyl-phenyl)-3H-pyrido[4',3':4,5]thieno[3,2-d]pyrimidin-4-one
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C18H15FN4OS
 1
1
IC50 = 21 nM
   TI
   LI
   LO
   TS
CP0505322
3-azepan-1-yl-9-(dimethylnitroryl)pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-one
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C17H21N5O2S
 1
1
IC50 = 33 nM
   TI
   LI
   LO
   TS
CP0141727
3-(4-Ethyl-phenyl)-9-[methyl-(2-pyridin-2-yl-ethyl)-amino]-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one
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C25H23N5OS
 1
1
IC50 = 52 nM
   TI
   LI
   LO
   TS