| Compound ID |
Compound Name |
Compound Formula |
|
CP0958663
|
2-(pyridin-2-yl)-4-(2,2,2-trifluoroethoxy)-6-((2,3,4-trifluorophenoxy)methyl)pyrimidine
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|
C18H11F6N3O2
|
1
|
| 1 |
IC50 = 7.943 nM
|
|
|
|
CP0958662
|
4-(cyclobutylmethoxy)-2-(pyridin-2-yl)-6-((2,3,4-trifluorophenoxy)methyl)pyrimidine
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|
C21H18F3N3O2
|
1
|
| 1 |
IC50 = 12.59 nM
|
|
|
|
CP0871259
|
4-(3,3-dimethylazetidin-1-yl)-2-(pyridin-2-yl)-6-((2,3,4-trifluorophenoxy)methyl)pyrimidine
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|
C21H19F3N4O
|
1
|
| 1 |
IC50 = 25.12 nM
|
|
|
|
CP0695194
|
4-((3-fluorooxetan-3-yl)methoxy)-2-(pyridin-2-yl)-6-((2,3,4-trifluorophenoxy)methyl)pyrimidine
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|
C20H15F4N3O3
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0946977
|
4-((3-methyloxetan-3-yl)methoxy)-2-(pyridin-2-yl)-6-((2,3,4-trifluorophenoxy)methyl)pyrimidine
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|
C21H18F3N3O3
|
1
|
| 1 |
IC50 = 79.43 nM
|
|
|
|
CP0874263
|
6-((3-fluorophenoxy)methyl)-N-isopropyl-2-(pyridin-2-yl)pyrimidin-4-amine
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|
C19H19FN4O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0673937
|
3-methyl-1-(2-(pyridin-2-yl)-6-((2,3,4-trifluorophenoxy)methyl)pyrimidin-4-yl)azetidine-3-carbonitrile
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|
C21H16F3N5O
|
1
|
| 1 |
IC50 = 158.49 nM
|
|
|
|
CP0651052
|
4-methyl-2-(pyridin-2-yl)-6-((2,3,4-trifluorophenoxy)methyl)pyrimidine
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|
C17H12F3N3O
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0911670
|
4-((4-chlorophenoxy)methyl)-6-methyl-2-(pyridin-2-yl)pyrimidine
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|
C17H14ClN3O
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0946849
|
4-(2-benzylidenehydrazinyl)-6-methyl-2-phenylpyrimidine
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|
C18H16N4
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0954525
|
4-ethoxy-6-((3-fluorophenoxy)methyl)-2-(pyridin-2-yl)pyrimidine
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|
C18H16FN3O2
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0853607
|
4-(oxetan-3-ylmethoxy)-2-(pyridin-2-yl)-6-((2,3,4-trifluorophenoxy)methyl)pyrimidine
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|
C20H16F3N3O3
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0950357
|
4-((2-chlorophenoxy)methyl)-6-methyl-2-(pyridin-2-yl)pyrimidine
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|
C17H14ClN3O
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0846390
|
4-((2-fluorophenoxy)methyl)-6-methyl-2-(pyridin-2-yl)pyrimidine
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|
C17H14FN3O
|
1
|
| 1 |
IC50 = 398.11 nM
|
|
|
|
CP0871257
|
4-((2,4-difluorophenoxy)methyl)-6-methyl-2-(pyridin-2-yl)pyrimidine
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|
C17H13F2N3O
|
1
|
| 1 |
IC50 = 398.11 nM
|
|
|
|
CP0953264
|
2-(3-((2-(pyridin-2-yl)-6-((2,3,4-trifluorophenoxy)methyl)pyrimidin-4-yloxy)methyl)oxetan-3-yl)acetonitrile
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|
C22H17F3N4O3
|
1
|
| 1 |
IC50 = 398.11 nM
|
|
|
|
CP0953265
|
4-((3-chlorophenoxy)methyl)-6-methyl-2-(pyridin-2-yl)pyrimidine
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|
C17H14ClN3O
|
1
|
| 1 |
IC50 = 398.11 nM
|
|
|
|
CP0962990
|
4-methyl-2-(pyridin-2-yl)-6-((3,4,5-trifluorophenoxy)methyl)pyrimidine
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|
C17H12F3N3O
|
1
|
| 1 |
IC50 = 398.11 nM
|
|
|
|
CP0967546
|
4-((2,3-difluorophenoxy)methyl)-6-methyl-2-(pyridin-2-yl)pyrimidine
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|
C17H13F2N3O
|
1
|
| 1 |
IC50 = 398.11 nM
|
|
|
|
CP0968254
|
4-methyl-2-(pyridin-2-yl)-6-((2,4,5-trifluorophenoxy)methyl)pyrimidine
Show/Hide
|
C17H12F3N3O
|
1
|
| 1 |
IC50 = 398.11 nM
|
|
|
|
CP0857739
|
4-methyl-2-(pyridin-2-yl)-6-((2,3,5-trifluorophenoxy)methyl)pyrimidine
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|
C17H12F3N3O
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0868039
|
4-((3-methoxyoxetan-3-yl)methoxy)-2-(pyridin-2-yl)-6-((2,3,4-trifluorophenoxy)methyl)pyrimidine
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|
C21H18F3N3O4
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0950356
|
6-(2-(pyridin-2-yl)-6-((2,3,4-trifluorophenoxy)methyl)pyrimidin-4-yl)-1-oxa-6-azaspiro[3.3]heptane
Show/Hide
|
C21H17F3N4O2
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0966222
|
4-((3,4-difluorophenoxy)methyl)-6-methyl-2-(pyridin-2-yl)pyrimidine
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|
C17H13F2N3O
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0850615
|
4-(6-(phenoxymethyl)-2-(pyridin-2-yl)pyrimidin-4-yl)morpholine
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|
C20H20N4O2
|
1
|
| 1 |
IC50 = 630.96 nM
|
|
|
|
CP0867805
|
N-ethyl-6-((3-fluorophenoxy)methyl)-2-(pyridin-2-yl)pyrimidin-4-amine
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|
C18H17FN4O
|
1
|
| 1 |
IC50 = 630.96 nM
|
|
|
|
CP0871256
|
4-((4-fluorophenoxy)methyl)-6-methyl-2-(pyridin-2-yl)pyrimidine
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|
C17H14FN3O
|
1
|
| 1 |
IC50 = 630.96 nM
|
|
|
|
CP0871536
|
4-methyl-6-(phenoxymethyl)-2-(pyridin-2-yl)pyrimidine
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|
C17H15N3O
|
1
|
| 1 |
IC50 = 794.33 nM
|
|
|
|
CP0962988
|
4-((3-fluorophenoxy)methyl)-6-methyl-2-(pyridin-2-yl)pyrimidine
Show/Hide
|
C17H14FN3O
|
1
|
| 1 |
IC50 = 794.33 nM
|
|
|
|
CP0867804
|
4-((3-fluorophenoxy)methyl)-6-methoxy-2-(pyridin-2-yl)pyrimidine
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|
C17H14FN3O2
|
1
|
| 1 |
IC50 = 1258.93 nM
|
|
|
|
CP0871258
|
4-methyl-2-(pyridin-2-yl)-6-((2,4,6-trifluorophenoxy)methyl)pyrimidine
Show/Hide
|
C17H12F3N3O
|
1
|
| 1 |
IC50 = 1258.93 nM
|
|
|
|
CP0874262
|
6-((3-fluorophenoxy)methyl)-N,N-dimethyl-2-(pyridin-2-yl)pyrimidin-4-amine
Show/Hide
|
C18H17FN4O
|
1
|
| 1 |
IC50 = 1584.89 nM
|
|
|
|
CP0958508
|
4-methyl-2-(pyridin-2-yl)-6-((2,3,6-trifluorophenoxy)methyl)pyrimidine
Show/Hide
|
C17H12F3N3O
|
1
|
| 1 |
IC50 = 1584.89 nM
|
|
|
|
CP0868042
|
4-((2-methoxyphenoxy)methyl)-6-methyl-2-(pyridin-2-yl)pyrimidine
Show/Hide
|
C18H17N3O2
|
1
|
| 1 |
IC50 = 1995.26 nM
|
|
|
|
CP0901121
|
4-((3-methoxyphenoxy)methyl)-6-methyl-2-(pyridin-2-yl)pyrimidine
Show/Hide
|
C18H17N3O2
|
1
|
| 1 |
IC50 = 1995.26 nM
|
|
|
|
CP0902369
|
3-((6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl)methoxy)benzonitrile
Show/Hide
|
C18H14N4O
|
1
|
| 1 |
IC50 = 2511.89 nM
|
|
|
|
CP0874264
|
1-(2-(pyridin-2-yl)-6-((2,3,4-trifluorophenoxy)methyl)pyrimidin-4-yl)azetidin-3-ol
Show/Hide
|
C19H15F3N4O2
|
1
|
| 1 |
IC50 = 3162.28 nM
|
|
|
|
CP0868040
|
4-(3-methyl-3-(methylsulfonylmethyl)azetidin-1-yl)-2-(pyridin-2-yl)-6-((2,3,4-trifluorophenoxy)methyl)pyrimidine
Show/Hide
|
C22H21F3N4O3S
|
1
|
| 1 |
IC50 = 6309.57 nM
|
|
|
|
CP0902368
|
4-((4-methoxyphenoxy)methyl)-6-methyl-2-(pyridin-2-yl)pyrimidine
Show/Hide
|
C18H17N3O2
|
1
|
| 1 |
IC50 = 7943.28 nM
|
|
|
|
CP0901124
|
2-((6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl)methoxy)benzonitrile
Show/Hide
|
C18H14N4O
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0963868
|
4-((6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl)methoxy)benzonitrile
Show/Hide
|
C18H14N4O
|
1
|
| 1 |
IC50 = 31622.78 nM
|
|
|
|
CP0867803
|
N-(4-((6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl)methoxy)phenyl)acetamide
Show/Hide
|
C19H18N4O2
|
1
|
| 1 |
IC50 > 39810.72 nM
|
|
|
|
CP0871255
|
4-methyl-6-((3-(methylsulfonyl)phenoxy)methyl)-2-(pyridin-2-yl)pyrimidine
Show/Hide
|
C18H17N3O3S
|
1
|
| 1 |
IC50 > 39810.72 nM
|
|
|
|
CP0874253
|
4-methyl-6-((2-(methylsulfonyl)phenoxy)methyl)-2-(pyridin-2-yl)pyrimidine
Show/Hide
|
C18H17N3O3S
|
1
|
| 1 |
IC50 > 39810.72 nM
|
|
|
|
CP0874261
|
4-methyl-6-((4-(methylsulfonyl)phenoxy)methyl)-2-(pyridin-2-yl)pyrimidine
Show/Hide
|
C18H17N3O3S
|
1
|
| 1 |
IC50 > 39810.72 nM
|
|
|
|
CP0954524
|
N-(2-((6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl)methoxy)phenyl)acetamide
Show/Hide
|
C19H18N4O2
|
1
|
| 1 |
IC50 > 39810.72 nM
|
|
|
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CP0958507
|
N-(3-((6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl)methoxy)phenyl)acetamide
Show/Hide
|
C19H18N4O2
|
1
|
| 1 |
IC50 > 39810.72 nM
|
|
|
